| Description : |
Integrin alpha E beta 7 consist of two major subunits: Integrin alpha E (ITGAE) also known as CD103 (cluster of differentiation 103) and Integrin beta-7 is an integrin protein that in humans is encoded by the ITGB7 gene. Integrin alpha E beta 7 (CD103) is expressed mainly by cells of the T lymphocyte lineage within mucosal tissues. This is a strikingly narrow pattern of expression compared with that of other integrins. Lymphocytes expressing alpha E beta 7 are abundant in the gut and comprise a major part of the total T cell complement of the body. The effectiveness of lung transplantation is marred by the relatively high incidence of rejection. The lung normally contains a large population of lymphocytes in contact with the airway epithelium, a proportion of which expresses the mucosal integrin, alpha (E) (CD103) beta (7) . This integrin is not a homing receptor, but is thought to retain lymphocytes at the epithelial surface. |
| Source : |
Mammalian cells |
| Species : |
Human |
| Tag : |
C-MYC/DDK |
| Form : |
Lyophilized powder/frozen liquid |
| Molecular Mass : |
87.78 kDa |
| Protein Length : |
Met1-Leu798 |
| Endotoxin : |
< 1.0 EU/μg of the protein as determined by the LAL method. |
| Purity : |
>90% as determined by SDS-PAGE. |
| Notes : |
For research use only. |
| Storage : |
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. |
| Storage Buffer : |
Supplied as solution form in PBS or lyophilized from PBS. |
| Reconstitution : |
Reconstitute in sterile water for a stock solution. |
| Shipping : |
They are shipped out with dry ice/blue ice unless customers require otherwise. |
