Jam2

  • Official Full Name

    junctional adhesion molecule 2

  • Overview

    Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space.
  • Synonyms

    JAM2; junctional adhesion molecule 2; C21orf43; junctional adhesion molecule B; CD322; JAM B; JAMB; VE JAM; JAM-2; JAM-IT/VE-JAM; vascular endothelial junction-associated molecule; JAM-B; VEJAM; PRO245; VE-JAM;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Cell & Tissue Lysates
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus monkey
  • E.coli
  • HEK293
  • Human Cell
  • Mammalian Cell
  • Mammalian cells
  • Yeast
  • C
  • Fc
  • His
  • hFc
  • hIgG1
  • hIgG4
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human JAM2-174H Recombinant Human JAM2, Fc-tagged HEK293 Fc
Human JAM2-817H Recombinant Human JAM2 Mammalian Cell His
Human JAM2-7092H Recombinant Human JAM2, His-tagged E.coli His 21-238aa
Human JAM2-3602H Recombinant Human JAM2 Protein (Phe29-Asn236), C-Fc tagged Mammalian cells C-Fc Phe29-Asn236
Human JAM2-3129H Recombinant Human JAM2 protein, His-tagged E.coli His 29-238aa
Human JAM2-1428H Recombinant Human JAM2 Protein (29-238 aa), His-tagged Yeast His 29-238 aa
Human JAM2-5055H Recombinant Human JAM2 Protein (Met1-Ser238), C-His tagged Mammalian cells C-His Met1-Ser238
Human JAM2-1227H Recombinant Human JAM2 Protein (Tyr74-Val250), N-His tagged E.coli N-His Tyr74-Val250
Human JAM2-3187H Recombinant Human JAM2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human JAM2-3187H-B Recombinant Human JAM2 Protein Pre-coupled Magnetic Beads HEK293
Mouse Jam2-909M Active Recombinant Mouse Jam2 protein, hFc-tagged HEK293 hFc Met1-Asn236
Mouse Jam2-789M Recombinant Mouse Jam2 protein(Met1-Asn236), His-tagged HEK293 C-His Met1-Asn236
Mouse JAM2-2123MCL Recombinant Mouse JAM2 cell lysate Human Cell N/A
Rat Jam2-7493R Recombinant Rat Jam2 protein(Met1-Asn236), His-tagged HEK293 C-His Met1-Asn236
Rat Jam2-7492R Recombinant Rat Jam2 protein, hFc-tagged HEK293 hFc Met1-Asn236
Rat JAM2-1399RCL Recombinant Rat JAM2 cell lysate Human Cell N/A
Rat Jam2-1706R Recombinant Rat Jam2 Protein, His-tagged E.coli N-His Thr57-Asp233
Rhesus monkey JAM2-1734R Recombinant Rhesus Monkey JAM2 Protein HEK293 N/A
Rhesus monkey JAM2-1735R Recombinant Rhesus Monkey JAM2 Protein, hIgG1-tagged HEK293 hIgG1
Rhesus monkey JAM2-1736R Recombinant Rhesus Monkey JAM2 Protein, hIgG4-tagged HEK293 hIgG4
Chicken JAM2-1404C Recombinant Chicken JAM2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

Jam2 involved in several pathways and played different roles in them. We selected most pathways Jam2 participated on our site, such as Cell adhesion molecules (CAMs), Tight junction, Leukocyte transendothelial migration, which may be useful for your reference. Also, other proteins which involved in the same pathway with Jam2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cell adhesion molecules (CAMs)MPZL1L;H2-AA;CLDN10A;TIGIT;CNTNAP2A;MADCAM1;CD99;JAM3;PTPRC
Tight junctionPARD6A;MAGI1;YBX3;AKT2;CLDN5B;JAM2A;MYL12.2;GNAI1;MYH8
Leukocyte transendothelial migrationRAP1B;PRKCG;ARHGAP35;CLDN15;CLDN2;NCF1;CLDN3;MYL12B;OCLN
Epithelial cell signaling in Helicobacter pylori infectionATP6V1E1;MAPK11;ATP6V0B;ATP6V0D1;SRC;ATP6V0E1;F11R;TCIRG1;MAP3K14

Jam2 has several biochemical functions, for example, protein binding, protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Jam2 itself. We selected most functions Jam2 had, and list some proteins which have the same functions with Jam2. You can find most of the proteins on our site.

Function Related Protein
protein bindingPSMA2;RPS13;DRD4;HP1BP3;PSMB1;SHPRH;CHD4;AOC3;SSX5
protein heterodimerization activityAPITD1;HEYL;YWHAE;ATP4A;KATNA1;TXLNG;CUL5;BIK;CLCN3

Jam2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Jam2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Jam2.

PARD3; JAM3; TDP2; SOX8; YBX1; NME3; Pick1; CSNK1A1L; GPR20

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