kat7 Protein, K(lysine) acetyltransferase 7


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Official Full Name K(lysine) acetyltransferase 7
Background Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Specifically represses AR-mediated transcription.
Synonyms KAT7; K(lysine) acetyltransferase 7; HBO1; HBOA; MYST2; ZC2HC7; histone acetyltransferase KAT7; MYST-2; lysine acetyltransferase 7; histone acetyltransferase MYST2; MYST histone acetyltransferase 2; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2; histone acetyltransferase binding to ORC1;
    • Species :
    • Human
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Sf9 Insect Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human KAT7-1200H Recombinant Human KAT7 Protein (1-214 aa), GST-tagged E.coli GST
    Human KAT7-1601H Recombinant Human K(Lysine) Acetyltransferase 7, GST-tagged Sf9 Insect Cell GST
    Human KAT7-3999HCL Recombinant Human MYST2 293 Cell Lysate HEK293 N/A
    Human KAT7-5864H Recombinant Human KAT7 Protein, GST-tagged Wheat Germ GST
    Human KAT7-6956H Recombinant Human KAT7 , GST-tagged Sf9 Insect Cell GST
    Rat KAT7-3157R Recombinant Rat KAT7 Protein Mammalian Cell His

    kat7 involved in several pathways and played different roles in them. We selected most pathways kat7 participated on our site, such as Androgen receptor signaling pathway, Chromatin modifying enzymes, Chromatin organization, which may be useful for your reference. Also, other proteins which involved in the same pathway with kat7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Androgen receptor signaling pathway SMARCE1; HMGB2A; NR2C2; KAT7; ZMIZ1; CREBBP; RANBP9; CMTM2A; RAD54L2; HTATIP
    Chromatin modifying enzymes PBRM1; PADI6; RUVBL2; EP400; SMARCC1; PRDM16; CSRP2BP; WDR77; GATAD2AB; ELP4
    Chromatin organization TADA2B; SMARCB1; KDM1A; CCDC101; KDM2B; BRPF3; KDM4B; RBB4L; SAP18; ING5B
    HATs acetylate histones ATXN7; C17orf81; ING4; ELP3; ELP4; TADA2B; BRD1; ING3; PAX3A; MCRS1
    Regulation of Androgen receptor activity NR2C2; SMARCA2; APPBP2; KAT7; GATA2; SRY; NR2C1; SPDEF; TRIM24; SMARCE1

    kat7 has several biochemical functions, for example, histone acetyltransferase activity, protein binding, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by kat7 itself. We selected most functions kat7 had, and list some proteins which have the same functions with kat7. You can find most of the proteins on our site.

    Function Related Protein
    histone acetyltransferase activity CDYL; NCOA1; NCOA2; EP300; KAT7A; vnc; KAT8; CLOCK; KAT7; MED24
    protein binding HTR3E; UCP2; GDI2; APOA4; ATXN7L1; LMO4; VAMP7; SMAD1; MYOM1; CTDP1
    transcription factor activity, sequence-specific DNA binding RARAB; NFKB2; MYNN; NR1H4; DMRTC1C2; ZNF317; UBN1; NKX2-5; MYT1; CREBBP
    zinc ion binding ZNRF2; ZFP259; SNCA; PTGR1; C6AST1; TRAIP; CPA2; NPEPPS; ZDHHC19; NANOS3

    kat7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with kat7 here. Most of them are supplied by our site. Hope this information will be useful for your research of kat7.

    VIM; CDK11B; AR; BARD1; CEP126

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