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KAT7

Official Full Name

K(lysine) acetyltransferase 7
Overview

Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Specifically represses AR-mediated transcription.
Synonyms

KAT7; K(lysine) acetyltransferase 7; HBO1; HBOA; MYST2; ZC2HC7; histone acetyltransferase KAT7; MYST-2; lysine acetyltransferase 7; histone acetyltransferase MYST2; MYST histone acetyltransferase 2; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2; histone acetyltransferase binding to ORC1;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Rat

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Sf9 Insect Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	KAT7-1601H	Recombinant Human K(Lysine) Acetyltransferase 7, GST-tagged	Sf9 Insect Cell	GST		Inquiry
Human	KAT7-6956H	Recombinant Human KAT7 , GST-tagged	Sf9 Insect Cell	GST	Full length	Inquiry
Human	KAT7-3999HCL	Recombinant Human MYST2 293 Cell Lysate	HEK293	N/A		Inquiry
Human	KAT7-6627HF	Recombinant Full Length Human KAT7 Protein, GST-tagged	In Vitro Cell Free System	GST	611 amino acids	Inquiry
Human	KAT7-5864H	Recombinant Human KAT7 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	KAT7-1200H	Recombinant Human KAT7 Protein (1-214 aa), GST-tagged	E.coli	GST	1-214 aa	Inquiry
Rat	KAT7-3157R	Recombinant Rat KAT7 Protein	Mammalian Cell	His		Inquiry
Rat	KAT7-2813R-B	Recombinant Rat KAT7 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	KAT7-2813R	Recombinant Rat KAT7 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry

Involved Pathway
Protein Function
Interacting Protein
KAT7 Related Research Area

KAT7 involved in several pathways and played different roles in them. We selected most pathways KAT7 participated on our site, such as Androgen receptor signaling pathway, Chromatin modifying enzymes, Chromatin organization, which may be useful for your reference. Also, other proteins which involved in the same pathway with KAT7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Androgen receptor signaling pathway	CMTM2A;NR2C2;GNB2L1;CDKN1A;NCOA2;STUB1;CTNNB2;SVILA;JUN
Chromatin modifying enzymes	DR1;KDM4A;ENY2;GATAD2AB;SAP30L;BRD8;JMJD6;ELP4;PADI1
Chromatin organization	CSRP2BP;SMARCA4;KDM3B;MSL2;ARID2;SMARCC2;RBBP4;RBB4L;GATAD2B
HATs acetylate histones	KANSL2;ACTL6A;PAX3A;BRPF1;VPS72;ING5;ZZZ3;MSL2A;PHF20B
Regulation of Androgen receptor activity	SENP1;SRY;SPDEF;GATA2;KAT7;TRIM24;SMARCE1;APPBP2;NR0B1

KAT7 has several biochemical functions, for example, histone acetyltransferase activity, protein binding, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KAT7 itself. We selected most functions KAT7 had, and list some proteins which have the same functions with KAT7. You can find most of the proteins on our site.

Function	Related Protein
histone acetyltransferase activity	HTATIP;TAF1L;CDYL;KAT6A;CLOCK;CREBBP;NCOA2;KAT2A;MGEA5
protein binding	ERLIN2;USP10;ZNF624;NISCH;BET1;TBCB;AIPL1;TCF4;THEMIS2
transcription factor activity, sequence-specific DNA binding	ZSCAN2;PRRX2;POU3F2A;POU3F3B;MYCA;SIX2;HOXA4;ZIC2;MAFA
zinc ion binding	PARK2;RNF32;IFIH1;VDRA;PXN;POLR2K;MEP1A.2;MBD1;S100A5

KAT7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KAT7 here. Most of them are supplied by our site. Hope this information will be useful for your research of KAT7.

VIM; CDK11B; AR; BARD1; CEP126

Histone Acetyltransferases and Associated Proteins