Expand| Cat.No. : | KAT7-1200H |
| Product Overview : | Recombinant Human KAT7 Protein (1-214 aa) is produced by E. coli expression system. This protein is fused with a GST tag at the N-terminal. Research Area: Transcription. Protein Description: Partial. |
| Description : | Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Specifically represses AR-mediated transcription. |
| Source : | E. coli |
| Species : | Human |
| Tag : | GST |
| Form : | Tris-based buffer,50% glycerol |
| Molecular Mass : | 50.8 kDa |
| Protein length : | 1-214 aa |
| AA Sequence : | MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQDSSPVRNLQSFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQVVDFSDRETKNTADHDESPPRTPTGNAPSSESDIDISSPNVSHDESIAKDMSLKDSGSDLSHRPKRRRFHESYNFNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHN |
| Purity : | > 90% as determined by SDS-PAGE. |
| Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
| Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
| Concentration : | A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information. |
| Figure : |
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel. |
| Gene Name : | KAT7 K(lysine) acetyltransferase 7 [ Homo sapiens ] |
| Official Symbol : | KAT7 |
| Synonyms : | KAT7; HBO1; HBOA; MYST-2; MYST2; |
| Gene ID : | 11143 |
| mRNA Refseq : | NM_001199155 |
| Protein Refseq : | NP_001186084 |
| MIM : | 609880 |
| UniProt ID : | O95251 |
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