Recombinant Human KAT7 , GST-tagged

• Cat.No.: KAT7-6956H
• Product Overview: Recombinant full-length human KAT7 (MYST2) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: GST
• Protein Length: Full length
• Description: KAT7 or K (lysine) acetyltransferase 5 is a signaling protein that belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein which play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and non-histone proteins. KAT7 acts as a transcriptional inhibitor and inhibited AR-mediated transactivation of reporter constructs in CV-1 and PC-3 cells.KAT7 is part of a multisubunit complex that can acetylate histones H3 and H4.
• Form: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Molecular Mass: ~ 110 kDa
• Purity: >85%
• Applications: Western Blot
• Storage: Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles.
• Concentration: 0.1 μg/μ

Gene Information

• Gene Name: KAT7 K(lysine) acetyltransferase 7 [ Homo sapiens ]
• Official Symbol: KAT7
• Synonyms: KAT7; K(lysine) acetyltransferase 7; MYST histone acetyltransferase 2 , MYST2; histone acetyltransferase KAT7; HBO1; HBOA; histone acetyltransferase binding to ORC1; MYST-2; lysine acetyltransferase 7; histone acetyltransferase MYST2; MYST histone acetyltransferase 2; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2; MYST2
• Gene ID: 11143
• mRNA Refseq: NM_001199155
• Protein Refseq: NP_001186084
• MIM: 609880
• UniProt ID: O95251
• Chromosome Location: 17q21.32
• Pathway: Androgen Receptor Signaling Pathway, organism-specific biosystem; Regulation of Androgen receptor activity, organism-specific biosystem
• Function: histone acetyltransferase activity; metal ion binding; protein binding; sequence-specific DNA binding transcription factor activity; transferase activity, transferring acyl groups other than amino-acyl groups; zinc ion binding