|Official Full Name||low density lipoprotein receptor-related protein 6|
|Background||LRP5 and LRP6 are single-pass transmembrane proteins belonging to the low-density lipoprotein receptor (LDLR)-related protein family. Unlike other members of the LDLR family, LRP5 and LRP6 have four EGF and three LDLR repeats in the extracellular domain,|
|Synonyms||LRP6; low density lipoprotein receptor-related protein 6; low-density lipoprotein receptor-related protein 6; LRP-6; ADCAD2; FLJ90062; FLJ90421|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
LRP6 involved in several pathways and played different roles in them. We selected most pathways LRP6 participated on our site, such as Wnt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with LRP6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Wnt signaling pathway||LRP5; WNT1; PPP3CCA; PPP3R1; RHOAD; CXXC4; TCF7L2; WNT11B; APC; FZD3B|
LRP6 has several biochemical functions, for example, Wnt-activated receptor activity, Wnt-protein binding, apolipoprotein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LRP6 itself. We selected most functions LRP6 had, and list some proteins which have the same functions with LRP6. You can find most of the proteins on our site.
|Wnt-activated receptor activity||FZD3B; FZD7; FZD1; FZD2; LRP5L; FZD10; FZD8B; FZD8; FZD7B; FZD7A|
|Wnt-protein binding||FRZB; SFRP2; FZD6; FZD7; FZD2; FZD9B; FZD8B; Fzd4; LRP2A; FZD5|
|apolipoprotein binding||LIPC; ABCA1; MAPT; LRP1; PCSK9; CANX; LRP4; PLG; LPA; LPL|
|coreceptor activity involved in Wnt signaling pathway||LRP6|
|frizzled binding||WNT8A; WNT2BB; WNT1; WNT7B; SFRP1; FZD7; WNT7AA; WNT10B; DVL1B; RSPO3|
|identical protein binding||TARDBP; TNK2; DPY30; P2RX2; HCN4; SEPHS1; RABAC1; BAX; ASMT; ACY3|
|kinase inhibitor activity||SOCS1; RHOH; AHSG; LRP6|
|low-density lipoprotein receptor activity||VLDLR; OLR1; LRP12; LDLR; LRP6; CXCL16|
|protein binding||RABL2A; MPP5; SENP5; TGFBR2; TCEAL5; UGGT2; BMPR1B; NFATC3; IL17RA; RPL4|
|protein homodimerization activity||BHLHB9; EVLA; TESC; BAXA; CASQ2; DEM1; MTPAP; PDE2A; RAB11FIP4B; XBP1|
|receptor binding||HNF4A; ARPP19; FYNB; GRP; HSPA1A; CCDC129; NRG2B; DHRS4; ARPP19A; GBA|
|toxin transporter activity||SLC7A8; ABCG1; SLC17A3; LRP6; SLC22A2; SLC22A3|
|NOT toxin transporter activity||LRP5; LRP6|
LRP6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LRP6 here. Most of them are supplied by our site. Hope this information will be useful for your research of LRP6.
Fzd8; GSK3B; Axin1