Recombinant Human LRP6 Protein, N-His tagged, Avi-biotinylated
| Cat.No. : | LRP6-7875HB |
| Product Overview : | Recombinant Human LRP6 Protein with N-His tag and Avi-biotin was expressed in E. coli. |
| Availability | May 22, 2026 |
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| Species : | Human |
| Source : | E.coli |
| Tag : | His |
| Description : | This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined. |
| Form : | Lyophilized |
| Molecular Mass : | 32.2 kDa |
| AA Sequence : | MGSSHHHHHHGLNDIFEAQKIEWHESSGLVPRGSHMASMTGGQQMGRGSEFWIDSRQNMIRKAQEDGSQGFTVVVSSVPSQNLEIQPYDLSIDIYSRYIYWTCEATNVINVTRLDGRSVGVVLKGEQDRPRAVVVNPEKGYMYFTNLQERSPKIERAALDGTEREVLFFSGLSKPIALALDSRLGKLFWADSDLRRIESSDLSGANRIVLEDSNILQPVGLTVFENWLYWIDKQQQMIEKIDMTGREGRTKVQARIAQLSDIHAVKELNLQEYRQHPCAQDNGG |
| Endotoxin : | <1 EU/μg by LAL |
| Purity : | > 90% by SDS-PAGE |
| Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Storage Buffer : | Lyophilized from PBS, pH 7.4, 5% trehalose, 5% mannitol |
| Conjugation : | Biotin |
| Gene Name | LRP6 LDL receptor related protein 6 [ Homo sapiens (human) ] |
| Official Symbol | LRP6 |
| Synonyms | LRP6; LDL receptor related protein 6; ADCAD2; STHAG7; low-density lipoprotein receptor-related protein 6; LRP-6 |
| Gene ID | 4040 |
| mRNA Refseq | NM_002336 |
| Protein Refseq | NP_002327 |
| MIM | 603507 |
| UniProt ID | O75581 |
Not For Human Consumption!
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