Recombinant Human LRP6 protein, Mouse IgG Fc-tagged
Cat.No. : | LRP6-552H |
Product Overview : | Recombinant Human LRP6 (Ala20-Pro630) protein was fused to mouse IgG2a Fc tag at C-terminus and expressed in human 293 cells (HEK293). |
- Specification
- Gene Information
- Related Products
Description : | LRP6 is a transmembrane low-density lipoprotein receptor that shares a similar structure with LRP5. Low-density lipoprotein receptor-related protein 6 is a key component of the LRP5/LRP6/Frizzled co-receptor group that is involved in canonical Wnt pathway. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin. |
Source : | HEK293 |
Species : | Human |
Tag : | Mouse IgG Fc |
Predicted N Terminal : | Ala20 |
Form : | Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 95.8 kDa. The protein migrates as 55 kDa and 110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | Ala20-Pro630 |
Endotoxin : | Less than 0.1 EU per μg by the LAL method. |
Purity : | >90% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | LRP6 |
Official Symbol : | LRP6 |
Synonyms : | LRP6; low density lipoprotein receptor-related protein 6; low-density lipoprotein receptor-related protein 6; LRP-6; ADCAD2; FLJ90062; FLJ90421 |
Gene ID : | 4040 |
mRNA Refseq : | NM_002336 |
Protein Refseq : | NP_002327 |
MIM : | 603507 |
UniProt ID : | O75581 |
Products Types
◆ Recombinant Protein | ||
LRP6-7875HB | Recombinant Human LRP6 Protein, N-His tagged, Avi-biotinylated | +Inquiry |
LRP6-2372R | Recombinant Rhesus Macaque LRP6 Protein, His (Fc)-Avi-tagged | +Inquiry |
Lrp6-5166M | Recombinant Mouse Lrp6 Protein, His (Fc)-Avi-tagged | +Inquiry |
LRP6-122H | Recombinant Human LRP6 Protein, His (Fc)-Avi-tagged | +Inquiry |
Lrp6-1338M | Recombinant Mouse Lrp6 Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
LRP6-4654HCL | Recombinant Human LRP6 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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