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MELK

  • Official Full Name

    maternal embryonic leucine zipper kinase

  • Overview

    MELK (Maternal Embryonic Leucine zipper Kinase, MPK38, KIAA0175) is a member of the Snf1/AMPK related kinase family. It is implicated in stem cell renewal, cell cycle progression and pre-m-RNA splicing . MELK is also a marker for self-renewing multipotent
  • Synonyms

    MELK; maternal embryonic leucine zipper kinase; KIAA0175; pEg3 kinase; protein kinase Eg3; protein kinase PK38; tyrosine-protein kinase MELK; HPK38;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cell
  • Sf21
  • Sf9 Insect Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • N/A
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MELK-1430H Active Recombinant Human MELK, GST-tagged Sf9 Insect Cell GST 1-340 aa
Human MELK-136H Active Recombinant Human MELK(1-340) Protein, N-GST-tagged Sf21 GST 1-340 aa
Human MELK-730H Recombinant Human Maternal Embryonic Leucine Zipper Kinase Sf9 Insect Cell N/A
Human MELK-1059H Recombinant Human Maternal Embryonic Leucine Zipper Kinase, GST-tagged Sf9 Insect Cell GST
Human MELK-30097TH Recombinant Human MELK Sf9 Insect Cell N/A 340 amino acids
Human MELK-4368HCL Recombinant Human MELK 293 Cell Lysate HEK293 N/A
Human MELK-4388H Recombinant Human MELK protein, His&Myc-tagged E.coli His&Myc 1-340aa
Human MELK-1135H Recombinant Human MELK Protein (D3-V330), His tagged E.coli His D3-V330
Human MELK-4448H Active Recombinant Human MELK Protein, GST-tagged E.coli GST
Human MELK-4447H Recombinant Human MELK Protein, GST-tagged Wheat Germ GST
Human MELK-1134H Recombinant Human MELK Protein (D3-V330), Tag Free E.coli No tag D3-V330
Mouse MELK-9725M Recombinant Mouse MELK Protein Mammalian Cell His
Mouse MELK-5473M Recombinant Mouse MELK Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse MELK-5473M-B Recombinant Mouse MELK Protein Pre-coupled Magnetic Beads HEK293
Zebrafish MELK-11780Z Recombinant Zebrafish MELK Mammalian Cell His
Chicken MELK-3154C Recombinant Chicken MELK Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • MELK Related Research Area

MELK involved in several pathways and played different roles in them. We selected most pathways MELK participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MELK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

MELK has several biochemical functions, for example, ATP binding, calcium ion binding, lipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MELK itself. We selected most functions MELK had, and list some proteins which have the same functions with MELK. You can find most of the proteins on our site.

Function Related Protein
ATP bindingCAMK4;DYRK1B;ATP11A;MAPK12A;VMHCL;KIFC2;TLK1A;SMC1B;PIK3CA
calcium ion bindingGM5077;CRB2;NUCB2A;PCLO;F9B;PCDHA8;PCDH10;ACTN1;CGREF1
lipid bindingSNX10B;CYP21A1;FABP7;RBP7B;FFAR1;CADPS;FABP10A;CRABP2B;AP2M1B
non-membrane spanning protein tyrosine kinase activityBAZ1B;JAK3;FYNB;FGR;FRK;CLK1;FER;TXK;FYN
protein bindingCDK20;CEP72;RBM26;RSPO2;TBC1D9B;RHOB;ABCG2;SLC35A2;WFDC9
protein serine/threonine kinase activityTGFBR1A;HIPK1;RPS6KA5;EIF2AK3;ULK1;MYO3A;NEK3;NLK2;MAP4K4

MELK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MELK here. Most of them are supplied by our site. Hope this information will be useful for your research of MELK.

BCL2L14; STK16; BABAM1; bosutinib; imatinib; purvalanol b; midostaurin; CDC5L

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