Recombinant Human MELK

• Cat.No.: MELK-30097TH
• Product Overview: Recombinant fragment corresponding to amino acids 1-340 of Human MELK with N-terminal proprietary tag; MWt 61 kDa.

Specification

• Description: Maternal embryonic leucine zipper kinase is an enzyme that in humans is encoded by the MELK gene.
• Protein length: 340 amino acids
• Molecular Weight: 61.000kDa inclusive of tags
• Source: Baculovirus infected sf9 cells
• Tissue specificity: Expressed in placenta, kidney, thymus, testis, ovary and intestine.
• Biological activity: The Specific activity of MELK-30097TH was determined to be 200 nmol/min/mg.
• Form: Liquid
• Purity: Densitometry
• Storage buffer: Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.Contains 1 KA1 (kinase-associated) domain.Contains 1 protein kinase domain.

Gene Information

• Gene Name: MELK maternal embryonic leucine zipper kinase [ Homo sapiens ]
• Official Symbol: MELK
• Synonyms: MELK; maternal embryonic leucine zipper kinase; KIAA0175
• Gene ID: 9833
• mRNA Refseq: NM_014791
• Protein Refseq: NP_055606
• MIM: 607025
• Uniprot ID: Q14680
• Chromosome Location: 9p13.1
• Function: ATP binding; calcium ion binding; lipid binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding