|Official Full Name||muscle, skeletal, receptor tyrosine kinase|
|Background||This gene encodes a muscle-specific tyrosine kinase receptor. The encoded protein may play a role in clustering of the acetylcholine receptor in the postsynaptic neuromuscular junction. Mutations in this gene have been associated with congenital myasthenic syndrome. Alternatively spliced transcript variants have been described.|
|Synonyms||MUSK; muscle, skeletal, receptor tyrosine kinase; muscle, skeletal receptor tyrosine-protein kinase; muscle-specific kinase receptor; muscle-specific tyrosine-protein kinase receptor; MGC126323; MGC126324|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
musk involved in several pathways and played different roles in them. We selected most pathways musk participated on our site, such as ECM proteoglycans, Extracellular matrix organization, which may be useful for your reference. Also, other proteins which involved in the same pathway with musk were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|ECM proteoglycans||MATN3; COMP; MATN1; COL9A1; HAPLN1; DMP1; ITGB3A; DAG1; LRP4; BGNB|
|Extracellular matrix organization||CTS7; COL6A3; COL9A3; COL5A1; ADAMTS3; COL17A1A; DST; ADAM8; LOX; CTSD|
musk has several biochemical functions, for example, ATP binding, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by musk itself. We selected most functions musk had, and list some proteins which have the same functions with musk. You can find most of the proteins on our site.
|ATP binding||TLK1B; TNIKB; MTHFD1B; PRKCZ; DDX19A; DDX52; UBE2U; TOR2A; ULK4; CSNK2A2|
|metal ion binding||TCN2; KDM5BA; MAP3K15; ZFP628; KLF8; ZFP354C; ZNF473; CYP2P6; ADCY7; ZFY1|
|protein binding||OBFC1; CADPS; ZFP64; DYNLRB1; ZRANB1; MSH2; SRPK2; SRPX2; SFRP4; ELK1|
|protein tyrosine kinase activity||PTK7; DSTYK; CLK2; INSRB; ERBB4; PDGFRB; MAP2K2; FYN; LYN; KITB|
|transmembrane receptor protein tyrosine kinase activity||ROR1; IGF1RA; EPHB4; ERBB4; KITA; CADM2B; EK1; EPHA2; TEK; MUSK|
musk has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with musk here. Most of them are supplied by our site. Hope this information will be useful for your research of musk.
HSP90AB1; HSP90AA1; FKBP5; CDC37; HSP90AB1; Chrnb1