Active Recombinant Human MUSK, GST-tagged
| Cat.No. : | MUSK-1434H |
| Product Overview : | Recombinant human MUSK (519-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
| Description : | MUSK is a receptor tyrosine kinase necessary for neuromuscular junction formation. MUSK gene expression is highly regulated during neuromuscular junction and it is involved in intercellular communication present on the surface of cells that are activated by specific protein ligands. MUSK members play a key role in growth and differentiation of those cell types. Agrin signals through MUSK to cluster acetylcholine receptors on the postsynaptic membrane of the neuromuscular junction. DOK7, a MUSK-interacting cytoplasmic protein, is essential for MUSK activation in cultured myotubes. MUSK also plays a critical role in the development of normal blood vessels. |
| Source : | Sf9 Cells |
| Species : | Human |
| Tag : | GST |
| Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. |
| Bio-activity : | 6.7 nmol/min/mg |
| Molecular Mass : | ~63 kDa |
| Protein length : | 519 aa-end |
| Purity : | >85% |
| Applications : | Kinase Assay, Western Blot |
| Storage : | Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles. |
| Concentration : | 0.1μg/μl |
| Gene Name : | MUSK muscle, skeletal, receptor tyrosine kinase [ Homo sapiens ] |
| Official Symbol : | MUSK |
| Synonyms : | MUSK; muscle, skeletal, receptor tyrosine kinase; muscle, skeletal receptor tyrosine-protein kinase; muscle-specific kinase receptor; muscle-specific tyrosine-protein kinase receptor; MGC126323; MGC126324; |
| Gene ID : | 4593 |
| mRNA Refseq : | NM_001166280 |
| Protein Refseq : | NP_001159752 |
| MIM : | 601296 |
| UniProt ID : | O15146 |
| Chromosome Location : | 9q31.3-q32 |
| Function : | ATP binding; PDZ domain binding; nucleotide binding; protein tyrosine kinase activity; receptor activity; transmembrane receptor protein tyrosine kinase activity; |
Products Types
| ◆ Recombinant Protein | ||
| MUSK-1288M | Recombinant Mouse MUSK Protein, His-SUMO/MYC-tagged | +Inquiry |
| MUSK-3547H | Recombinant Human MUSK Protein, His (Fc)-Avi-tagged | +Inquiry |
| MUSK-2372H | Recombinant Human MUSK Protein (24-495 aa), His-tagged | +Inquiry |
| MUSK-5457H | Recombinant Human Muscle, Skeletal, Receptor Tyrosine Kinase, GST-tagged | +Inquiry |
| MUSK-2466H | Recombinant Human MUSK Protein, His-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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