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Official Full Name myosin, light chain 4, alkali; atrial, embryonic
Background Myosin is a hexameric ATPase cellular motor protein. It is composed of two myosin heavy chains, two nonphosphorylatable myosin alkali light chains, and two phosphorylatable myosin regulatory light chains. This gene encodes a myosin alkali light chain that is found in embryonic muscle and adult atria. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
Synonyms MYL4; myosin, light chain 4, alkali; atrial, embryonic; myosin, light polypeptide 4, alkali; myosin light chain 4; ALC1; AMLC; GT1; myosin; atrial/fetal muscle; light chain; PRO1957; embryonic muscle/atrial isoform; ALC 1; Atrial/embryonic alkali myosin light chain; GT 1; MLC 1; MLC1; MYL 4; MYL4_HUMAN; Myosin atrial/fetal muscle light chain; Myosin light chain 1; Myosin light chain 1 embryonic muscle/atrial isoform; Myosin light chain 4 alkali atrial embryonic; Myosin light chain alkali GT 1 isoform; Myosin light chain alkali GT-1 isoform; Myosin light polypeptide 4 alkali atrial embryonic; Myosin light polypeptide 4; myosin, atrial/fetal muscle, light chain; myosin light chain 1, embryonic muscle/atrial isoform
    • Species :
    • Chicken
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MYL4-1355H Recombinant Human MYL4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human MYL4-1565H Recombinant Human MYL4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human MYL4-29362TH Recombinant Human MYL4 Wheat Germ N/A
    Human MYL4-30265TH Recombinant Human MYL4, His-tagged E.coli His
    Human MYL4-4026HCL Recombinant Human MYL4 293 Cell Lysate HEK293 N/A
    Human MYL4-4751H Recombinant Human MYL4, His-tagged Human His
    Human MYL4-5811H Recombinant Human MYL4 Protein, GST-tagged Wheat Germ GST
    Human MYL4-6857H Recombinant Human Myosin, Light Chain 4, Alkali; Atrial, Embryonic, His-tagged E.coli His
    Mouse Myl4-4252M Recombinant Mouse Myl4 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse Myl4-8029M Recombinant Mouse Myl4 protein, His-tagged E.coli His
    Chicken MYL4-7028C Recombinant Chicken MYL4 Mammalian Cell His
    Zebrafish MYL4-3085Z Recombinant Zebrafish MYL4 Mammalian Cell His

    myl4 involved in several pathways and played different roles in them. We selected most pathways myl4 participated on our site, such as Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, which may be useful for your reference. Also, other proteins which involved in the same pathway with myl4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cardiac muscle contraction TPM4B; COX8C; VMHC; ACTC1A; CACNG2A; CACNB1; SLC9A1; COX6A1; ATP1B2A; CACNB3
    Adrenergic signaling in cardiomyocytes GNAI1; SCN4BA; ATP1B1; SCN1BB; MAPK12B; CACNA2D4; CACNA2D1A; MYL2B; ADCY1; ADRB2

    myl4 has several biochemical functions, for example, actin filament binding, actin monomer binding, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by myl4 itself. We selected most functions myl4 had, and list some proteins which have the same functions with myl4. You can find most of the proteins on our site.

    Function Related Protein
    actin filament binding CTNNA1; KLHL17; AIF1; MYH3; SMYHC2; CORO1B; FSCN1A; ANXA8; TULP1; MYO1E
    actin monomer binding MKL1; MKL1B; TMSB4Y; TWF1; PRKCE; MYL2; ABL1; COBL; NOS3; CORO1A
    calcium ion binding AGRN; PCDH2AB5; CALB2A; PCDHGA4; S100A13; EDEM2; CSN2; RHOT1; S100V2; NUCB1
    myosin II heavy chain binding MYL3; MYL4

    myl4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with myl4 here. Most of them are supplied by our site. Hope this information will be useful for your research of myl4.


    Lisowski, P; Juszczak, GR; et al. Stress susceptibility-specific phenotype associated with different hippocampal transcriptomic responses to chronic tricyclic antidepressant treatment in mice. BMC NEUROSCIENCE 14:-(2013).
    Cheng, W; Yu, Z; et al. Perfluorooctane sulfonate (PFOS) induced embryotoxicity and disruption of cardiogenesis. TOXICOLOGY IN VITRO 27:1503-1512(2013).

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