myl5

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myl5

Official Full Name myosin, light chain 5, regulatory
Background This gene encodes one of the myosin light chains, a component of the hexameric ATPase cellular motor protein myosin. Myosin is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene product, one of the regulatory light chains, is expressed in fetal muscle and in adult retina, cerebellum, and basal ganglia.
Synonyms MYL5; myosin, light chain 5, regulatory; myosin, light polypeptide 5, regulatory; myosin light chain 5; MYL 5; MYL5_HUMAN; MyLC 2; MyLC-2; MYLC2; Myosin light chain 5 regulatory; Myosin light polypeptide 5; Myosin light polypeptide 5 regulatory; Myosin regulatory light chain 5; Superfast myosin regulatory light chain 2; OTTHUMP00000217187; OTTHUMP00000217188; OTTHUMP00000217190; OTTHUMP00000217193
    • Species :
    • Human
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MYL5-2489H Recombinant Human MYL5 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human MYL5-29364TH Recombinant Human MYL5, His-tagged E.coli His
    Human MYL5-3622H Recombinant Human MYL5, His-tagged Human His
    Human MYL5-4025HCL Recombinant Human MYL5 293 Cell Lysate HEK293 N/A
    Human MYL5-5812H Recombinant Human MYL5 Protein, GST-tagged Wheat Germ GST
    Human MYL5-6875H Recombinant Human Myosin, Light Chain 5, Regulatory, His-tagged E.coli His

    myl5 involved in several pathways and played different roles in them. We selected most pathways myl5 participated on our site, such as Focal adhesion, Tight junction, Leukocyte transendothelial migration, which may be useful for your reference. Also, other proteins which involved in the same pathway with myl5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Focal adhesion SHC3; MYL12.1; HRAS; HRASB; MYL12.2; PTK2; VEGFAA; ITGB5; COL1A1A; RAC2
    Tight junction PPP2R2A; EXOC4; CLDNF; YES1; CDC42; CLDN1; PARD6A; MYL7; CLDN11A; SHROOM1
    Leukocyte transendothelial migration VCL; PIK3R3; RAP1B; ARHGAP35; ITGAM; MYL9; PIK3R5; ITGB2L; NCF1; PLCG2
    Regulation of actin cytoskeleton WASB; FGFR1A; LIMK2; PIK3CG; CFL2; CFL2L; MYL12.1; PDGFC; INSRR; ITGAE

    myl5 has several biochemical functions, for example, calcium ion binding, structural constituent of muscle. Some of the functions are cooperated with other proteins, some of the functions could acted by myl5 itself. We selected most functions myl5 had, and list some proteins which have the same functions with myl5. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding EFHC2; EYS; FREM2; MGMT; DNASE1L3; SYT5A; LDLR; ZFP652; PCDHB1; FLG2
    structural constituent of muscle ASPH; MYBPC3; CSRP3; MYL2; MYL5; ACTN3; MYOM1; MYBPH; DMD; SYNM

    myl5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with myl5 here. Most of them are supplied by our site. Hope this information will be useful for your research of myl5.

    Kakei, T; Sumiyoshi, H; et al. Characteristics of light chains of Chara myosin revealed by immunological investigation. PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES 88:201-211(2012).
    Vicente-Manzanares, M; Horwitz, AR; et al. Myosin light chain mono- and di-phosphorylation differentially regulate adhesion and polarity in migrating cells. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 402:537-542(2010).

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