nr4a1

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nr4a1

Official Full Name nuclear receptor subfamily 4, group A, member 1
Background Nur77, also known as TR3 and NGFI-B, is an immediate-early response gene and an orphan member of the steroid/thyroid/retinoid receptor superfamily (1-3). Nur77 is composed of an amino-terminal transactivation domain, a central DNA-binding domain and a car
Synonyms NR4A1; nuclear receptor subfamily 4, group A, member 1; nuclear receptor subfamily 4 group A member 1; hormone receptor; nuclear protein N10; orphan nuclear receptor HMR; nuclear hormone receptor NUR/77; Hmr; N10; TR3; Gfrp; Hbr1; NP10; TIS1; GFRP1; Hbr-1; NGFIB; nur77; NGFI-B
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • MYC/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human NR4A1-1219HCL Recombinant Human NR4A1 cell lysate N/A
    Human NR4A1-12H Recombinant Human NR4A1 protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human NR4A1-1360H Recombinant Human NR4A1, GST-tagged E.coli GST
    Human NR4A1-28049TH Recombinant Human NR4A1 Wheat Germ N/A
    Human NR4A1-30494TH Recombinant Human NR4A1 Wheat Germ N/A
    Human NR4A1-4396H Recombinant Human NR4A1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human NR4A1-6093H Recombinant Human NR4A1 Protein, GST-tagged Wheat Germ GST
    Mouse NR4A1-10871M Recombinant Mouse NR4A1 Protein Mammalian Cell His
    Mouse Nr4a1-1143M Recombinant Mouse Nr4a1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Rat NR4A1-4070R Recombinant Rat NR4A1 Protein Mammalian Cell His
    Zebrafish NR4A1-394Z Recombinant Zebrafish NR4A1 Mammalian Cell His

    nr4a1 involved in several pathways and played different roles in them. We selected most pathways nr4a1 participated on our site, such as MAPK signaling pathway, PIK-Akt signaling pathway, Aldosterone synthesis and secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with nr4a1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway TRAF6; CACNA1BA; IL1R2; ARRB1; FGF14; CACNB3A; NGF; RPS6KA5; FGF6B; PLA2G4AA
    PIK-Akt signaling pathway PTEN; IFNA10; IL6; SOS1; PIK3CD; IFNA7; IFNA14; FGF21; IKBKB; Itga10&Itgb1
    Aldosterone synthesis and secretion CYP11A1; AGTR1A; PRKCE; CYP11B2; ITPR3; PRKD1; CAMK2D; LIPE; CREB3L2; AGTR1

    nr4a1 has several biochemical functions, for example, DNA binding, RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by nr4a1 itself. We selected most functions nr4a1 had, and list some proteins which have the same functions with nr4a1. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding HOXB1B; RYBPA; IMPDH2; ERCC6L; HIST1H2AM; XPC; SCML4; POLR3C; POLD1; RCAN1
    RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding PPARA; NR2F2; Ar; PPARAB; NR0B1; RORA; PPARAA; RORCA; NR2F1; HNF4A
    protein binding CRYGD; PPP1R1A; MAP2K6; SHMT2; H2AFX; ATG4B; TOLLIP; FER; U2AF2; UACA
    protein heterodimerization activity ATP4A; TIMELESS; HIST1H2BN; NEUROD1; TAF9; PPP2R4; HNF1B; ANO2; VEGFB; HOMER1
    sequence-specific DNA binding RAX2; OTPB; HOXC13B; LONP1; DLX1A; POU3F1; EVX1; HOXA4A; ZFP423; SHOX
    steroid hormone receptor activity NR2F2; ESR1; HNF4G; RORCA; NR4A2B; VDRB; RARB; RARGB; RXRBB; ESR2A
    transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding IRF4; RUNX2; DBP; ESRRA; FUBP3; GRHL1; STAT3; ELK1; GABPA; HMGA2
    zinc ion binding ADH5; MEP1A.2; APOBEC1; TRIM37; MLLT6; PDLIM2; DPF2L; SNCA; PARP1; CPA2

    nr4a1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with nr4a1 here. Most of them are supplied by our site. Hope this information will be useful for your research of nr4a1.

    BCL2; TP53; GK; 386677

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