Official Full Name
purinergic receptor P2Y, G-protein coupled, 12
BackgroundThe product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelets aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Two transcript variants encoding the same isoform have been identified for this gene.
SynonymsP2RY12; purinergic receptor P2Y, G-protein coupled, 12; P2Y purinoceptor 12; HORK3; P2Y12; SP1999; ADP-glucose receptor; purinergic receptor P2RY12; P2Y12 platelet ADP receptor; Gi-coupled ADP receptor HORK3; G-protein coupled receptor SP1999; putative G-;