P2RY12

  • Official Full Name

    purinergic receptor P2Y, G-protein coupled, 12

  • Overview

    The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelets aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Two transcript variants encoding the same isoform have been identified for this gene.
  • Synonyms

    P2RY12; purinergic receptor P2Y, G-protein coupled, 12; P2Y purinoceptor 12; HORK3; P2Y12; SP1999; ADP-glucose receptor; purinergic receptor P2RY12; P2Y12 platelet ADP receptor; Gi-coupled ADP receptor HORK3; G-protein coupled receptor SP1999; putative G-;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Cynomolgus Monkey
  • Homo sapiens (Human)
  • Human
  • Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • Rhesus Macaque
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • In vitro E. coli expression system
  • Mammalian Cell
  • Mammalian cells
  • C
  • Fc
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human P2RY12-1497H Recombinant Human P2RY12, GST-tagged E.coli GST 1-342aa
Human P2RY12-3492HCL Recombinant Human P2RY12 293 Cell Lysate HEK293 N/A
Human P2RY12-3491HCL Recombinant Human P2RY12 293 Cell Lysate HEK293 N/A
Human P2RY12-1103HFL Recombinant Human P2RY12 protein, His&Flag-tagged HEK293 His&Flag 1-342 aa
Human P2RY12-2840H Recombinant Human P2RY12 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human P2RY12-1595H-B Recombinant Human P2RY12 Protein Pre-coupled Magnetic Beads HEK293
Human P2RY12-1595H Recombinant Human P2RY12 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human P2RY12-2459H Recombinant Human P2RY12 Full Length Transmembrane protein, His-tagged In vitro E. coli expression system His 1-342aa
Human P2RY12-590HFL Recombinant Full Length Human P2RY12 Protein, C-Flag-tagged Mammalian cells Flag
Mouse P2ry12-9278M Recombinant Mouse P2ry12 Full Length Transmembrane protein, His-tagged In vitro E. coli expression system His 1-347aa
Mouse P2ry12-4638M Recombinant Mouse P2ry12 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse P2ry12-6461M Recombinant Mouse P2ry12 Protein (Full Length), C-Fc tagged Mammalian cells C-Fc Full Length
Rat P2RY12-4234R Recombinant Rat P2RY12 Protein Mammalian Cell His
Rat P2RY12-3896R Recombinant Rat P2RY12 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat P2RY12-3896R-B Recombinant Rat P2RY12 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey P2RY12-770C Recombinant Cynomolgus P2RY12 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey P2RY12-514C-B Recombinant Cynomolgus Monkey P2RY12 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey P2RY12-514C Recombinant Cynomolgus Monkey P2RY12 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Homo sapiens (Human) RFL33733HF Recombinant Full Length Human P2Y Purinoceptor 12(P2Ry12) Protein, His-Tagged E.coli expression system His Full Length (1-342)
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) RFL26948MF Recombinant Full Length Macaca Fascicularis P2Y Purinoceptor 12(P2Ry12) Protein, His-Tagged E.coli expression system His Full Length (1-342)
Mus musculus (Mouse) RFL28738MF Recombinant Full Length Mouse P2Y Purinoceptor 12(P2Ry12) Protein, His-Tagged E.coli expression system His Full Length (1-347aa)
Rattus norvegicus (Rat) RFL36153RF Recombinant Full Length Rat P2Y Purinoceptor 12(P2Ry12) Protein, His-Tagged E.coli expression system His Full Length (1-343)
Rhesus Macaque P2RY12-3272R Recombinant Rhesus monkey P2RY12 Protein, His-tagged Mammalian Cell His
Rhesus Macaque P2RY12-3090R Recombinant Rhesus Macaque P2RY12 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque P2RY12-3090R-B Recombinant Rhesus Macaque P2RY12 Protein Pre-coupled Magnetic Beads HEK293
Kit-0917 CYP2B6 Blue Screening Kit N/A
Kit-1470 P2RY12 CHO-K1 β-Arrestin GPCR Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

P2RY12 involved in several pathways and played different roles in them. We selected most pathways P2RY12 participated on our site, such as Platelet activation, which may be useful for your reference. Also, other proteins which involved in the same pathway with P2RY12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Platelet activationPIK3R1;PLCB3;ARHGEF12;TBXAS1;PIK3R5;MYL12A;MAPK1;ITGA2;FGG

P2RY12 has several biochemical functions, for example, ADP receptor activity, G-protein coupled adenosine receptor activity, guanyl-nucleotide exchange factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by P2RY12 itself. We selected most functions P2RY12 had, and list some proteins which have the same functions with P2RY12. You can find most of the proteins on our site.

Function Related Protein
ADP receptor activity
G-protein coupled adenosine receptor activityADORA2AA;ADORA3;ADORA2A;P2RY12;ADORA1;ADORA2AB;ADORA2B
guanyl-nucleotide exchange factor activityPLCE1;DOCK7;FAM116B;SH2D3CB;GAPVD1;DENND6A;RASGEF1BB;TRIO;SH2D3C

P2RY12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with P2RY12 here. Most of them are supplied by our site. Hope this information will be useful for your research of P2RY12.

  • Q&As
  • Reviews

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Customer Reviews (3)

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Reviews
04/23/2019

    As the most reliable assistant in my experiments, nothing surpasses this protein reagent.

    10/30/2016

      The manufacturer's reliability ensures that I can use it with complete peace of mind.

      01/31/2016

        The performance of this protein substance is truly remarkable! Its stability and accuracy instill confidence in my experimental results, and the manufacturer's quality control is highly dependable.

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