P2RY12

  • Official Full Name

    purinergic receptor P2Y, G-protein coupled, 12

  • Background

    The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelets aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Two transcript variants encoding the same isoform have been identified for this gene.
  • Synonyms

    P2RY12; purinergic receptor P2Y, G-protein coupled, 12; P2Y purinoceptor 12; HORK3; P2Y12; SP1999; ADP-glucose receptor; purinergic receptor P2RY12; P2Y12 platelet ADP receptor; Gi-coupled ADP receptor HORK3; G-protein coupled receptor SP1999; putative G-;
    • Type:
    • Assay Kits
    • Recombinant Proteins
    • Protein Pre-coupled Magnetic Beads
    • Cell & Tissue Lysates
    • Species :
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • In vitro E. coli expression system
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • His (Fc)
    • Avi
    • Flag
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Kit-0917 CYP2B6 Blue Screening Kit N/A
    Kit-1470 P2RY12 CHO-K1 β-Arrestin GPCR Assay Kit N/A
    Cynomolgus Monkey P2RY12-770C Recombinant Cynomolgus P2RY12 Protein, His-tagged Mammalian Cell His
    Cynomolgus Monkey P2RY12-514C-B Recombinant Cynomolgus Monkey P2RY12 Protein Pre-coupled Magnetic Beads HEK293
    Cynomolgus Monkey P2RY12-514C Recombinant Cynomolgus Monkey P2RY12 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Human P2RY12-1103HFL Recombinant Human P2RY12 protein, His&Flag-tagged HEK293 His&Flag
    Human P2RY12-2840H Recombinant Human P2RY12 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human P2RY12-3492HCL Recombinant Human P2RY12 293 Cell Lysate HEK293 N/A
    Human P2RY12-1595H-B Recombinant Human P2RY12 Protein Pre-coupled Magnetic Beads HEK293
    Human P2RY12-1595H Recombinant Human P2RY12 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Human P2RY12-3491HCL Recombinant Human P2RY12 293 Cell Lysate HEK293 N/A
    Human P2RY12-1497H Recombinant Human P2RY12, GST-tagged E.coli GST
    Human P2RY12-2459H Recombinant Human P2RY12 protein, His-tagged E.coli His
    Mouse P2ry12-9278M Recombinant Mouse P2ry12 Full Length Transmembrane protein, His-tagged In vitro E. coli expression system His
    Mouse P2ry12-4638M Recombinant Mouse P2ry12 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Rat P2RY12-4234R Recombinant Rat P2RY12 Protein Mammalian Cell His
    Rat P2RY12-3896R Recombinant Rat P2RY12 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Rat P2RY12-3896R-B Recombinant Rat P2RY12 Protein Pre-coupled Magnetic Beads HEK293
    Rhesus Macaque P2RY12-3272R Recombinant Rhesus monkey P2RY12 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque P2RY12-3090R Recombinant Rhesus Macaque P2RY12 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Rhesus Macaque P2RY12-3090R-B Recombinant Rhesus Macaque P2RY12 Protein Pre-coupled Magnetic Beads HEK293
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • P2RY12 Related Research Area

    P2RY12 involved in several pathways and played different roles in them. We selected most pathways P2RY12 participated on our site, such as Platelet activation, which may be useful for your reference. Also, other proteins which involved in the same pathway with P2RY12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Platelet activationPPP1R12A;MYL12B;VASP;P2RY12;PTGIR;P2RX1;PRKG1;BTK;SNAP23

    P2RY12 has several biochemical functions, for example, ADP receptor activity, G-protein coupled adenosine receptor activity, guanyl-nucleotide exchange factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by P2RY12 itself. We selected most functions P2RY12 had, and list some proteins which have the same functions with P2RY12. You can find most of the proteins on our site.

    Function Related Protein
    ADP receptor activity
    G-protein coupled adenosine receptor activityP2RY12;ADORA2A;ADORA2AA;ADORA2B;ADORA1;ADORA3;ADORA2AB
    guanyl-nucleotide exchange factor activityDOCK6;TBXAS1;DOCK4;FGD3;P2RY12;DOCK7;ARHGEF3L;SBF1;PRSS56

    P2RY12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with P2RY12 here. Most of them are supplied by our site. Hope this information will be useful for your research of P2RY12.

    • Q&As
    • Reviews

    Q&As (0)

    Ask a question

    Customer Reviews (0)

    Write a review

    Ask a Question for All P2RY12 Products

    Required fields are marked with *

    My Review for All P2RY12 Products

    Required fields are marked with *

    logo

    Stay Updated on the
    Latest Bioscience Trends

    Copyright © 2023 Creative BioMart. All Rights Reserved.

    Terms and Conditions        Privacy Policy