Recombinant Full Length Human P2RY12 Protein, C-Flag-tagged

Cat.No. : P2RY12-590HFL
Product Overview : Recombinant Full Length Human P2RY12 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.
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Description : The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene.
Source : Mammalian cells
Species : Human
Tag : Flag
Form : 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 39.3 kDa
AA Sequence : MQAVDNLTSAPGNTSLCTRDYKITQ VLFPLLYTVLFFVGLITNGLAMRIF FQIRSKSNFIIFLKNTVISD LLMILTFPFKILSDAKLGTGPLRTF VCQVTSVIFYFTMYISISFLGLITI DRYQKTTRPFKTSNPKNLLG AKILSVVIWAFMFLLSLPNMILTNR QPRDKNVKKCSFLKSEFGLVWHEIV NYICQVIFWINFLIVIVCYT LITKELYRSYVRTRGVGKVPRKKVN VKVFIIIAVFFICFVPFHFARIPYT LSQTRDVFDCTAENTLFYVK
ESTLWLTSLNACLDPFIYFFLCKSF RNSLISMLKCPNSATSLSQDNRKKE QDGGDPNEETPMTRTRPLEQKLISE EDLAANDILDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining.
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade.
Concentration : >50 ug/mL as determined by microplate BCA method.
Preparation : Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families : Druggable Genome, GPCR, Transmembrane
SDS-PAGE: Coomassie blue staining of purified P2RY12 protein.
Gene Name : P2RY12 purinergic receptor P2Y12 [ Homo sapiens (human) ]
Official Symbol : P2RY12
Synonyms : HORK3; P2Y12; ADPG-R; BDPLT8; SP1999; P2T(AC); P2Y(AC); P2Y(12)R; P2Y(ADP); P2Y(cyc)
Gene ID : 64805
mRNA Refseq : NM_022788.5
Protein Refseq : NP_073625.1
MIM : 600515
UniProt ID : Q9H244

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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04/23/2019

    As the most reliable assistant in my experiments, nothing surpasses this protein reagent.

    10/30/2016

      The manufacturer's reliability ensures that I can use it with complete peace of mind.

      01/31/2016

        The performance of this protein substance is truly remarkable! Its stability and accuracy instill confidence in my experimental results, and the manufacturer's quality control is highly dependable.

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