Recombinant Full Length Human P2RY12 Protein, C-Flag-tagged
Cat.No. : | P2RY12-590HFL |
Product Overview : | Recombinant Full Length Human P2RY12 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 39.3 kDa |
AA Sequence : | MQAVDNLTSAPGNTSLCTRDYKITQ VLFPLLYTVLFFVGLITNGLAMRIF FQIRSKSNFIIFLKNTVISD LLMILTFPFKILSDAKLGTGPLRTF VCQVTSVIFYFTMYISISFLGLITI DRYQKTTRPFKTSNPKNLLG AKILSVVIWAFMFLLSLPNMILTNR QPRDKNVKKCSFLKSEFGLVWHEIV NYICQVIFWINFLIVIVCYT LITKELYRSYVRTRGVGKVPRKKVN VKVFIIIAVFFICFVPFHFARIPYT LSQTRDVFDCTAENTLFYVK ESTLWLTSLNACLDPFIYFFLCKSF RNSLISMLKCPNSATSLSQDNRKKE QDGGDPNEETPMTRTRPLEQKLISE EDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome, GPCR, Transmembrane |
Gene Name : | P2RY12 purinergic receptor P2Y12 [ Homo sapiens (human) ] |
Official Symbol : | P2RY12 |
Synonyms : | HORK3; P2Y12; ADPG-R; BDPLT8; SP1999; P2T(AC); P2Y(AC); P2Y(12)R; P2Y(ADP); P2Y(cyc) |
Gene ID : | 64805 |
mRNA Refseq : | NM_022788.5 |
Protein Refseq : | NP_073625.1 |
MIM : | 600515 |
UniProt ID : | Q9H244 |
Products Types
◆ Recombinant Protein | ||
P2ry12-4638M | Recombinant Mouse P2ry12 Protein, Myc/DDK-tagged | +Inquiry |
P2RY12-1595H | Recombinant Human P2RY12 Protein, His (Fc)-Avi-tagged | +Inquiry |
P2RY12-3090R | Recombinant Rhesus Macaque P2RY12 Protein, His (Fc)-Avi-tagged | +Inquiry |
P2RY12-514C | Recombinant Cynomolgus Monkey P2RY12 Protein, His (Fc)-Avi-tagged | +Inquiry |
P2RY12-3896R | Recombinant Rat P2RY12 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
P2RY12-3491HCL | Recombinant Human P2RY12 293 Cell Lysate | +Inquiry |
P2RY12-3492HCL | Recombinant Human P2RY12 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-1470 | P2RY12 CHO-K1 β-Arrestin GPCR Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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