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PDCD6

  • Official Full Name

    programmed cell death 6

  • Overview

    This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant.
  • Synonyms

    PDCD6; programmed cell death 6; programmed cell death protein 6; ALG 2; apoptosis linked gene 2; PEF1B; apoptosis-linked gene-2; apoptosis-linked gene 2 protein; probable calcium-binding protein ALG-2; ALG-2; MGC9123; FLJ46208; MGC111017; MGC119050;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rhesus monkey
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Flag
  • GST
  • hIgG1
  • hIgG4
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PDCD6-1595H Recombinant Human PDCD6, GST-tagged E.coli GST 1-191aa
Human PDCD6-3427H Recombinant Human PDCD6 protein, His-tagged E.coli His
Human PDCD6-3359HCL Recombinant Human PDCD6 293 Cell Lysate HEK293 N/A
Human PDCD6-2556H Recombinant Human PDCD6 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PDCD6-1650HFL Recombinant Full Length Human PDCD6 Protein, C-Flag-tagged Mammalian cells Flag
Human PDCD6-1626H-B Recombinant Human PDCD6 Protein Pre-coupled Magnetic Beads HEK293
Human PDCD6-3853H Recombinant Human PDCD6 Protein (Phe32-Val191), N-His tagged E.coli N-His Phe32-Val191
Human PDCD6-1626H Recombinant Human PDCD6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse PDCD6-12537M Recombinant Mouse PDCD6 Protein Mammalian Cell His
Mouse PDCD6-6576M-B Recombinant Mouse PDCD6 Protein Pre-coupled Magnetic Beads HEK293
Mouse PDCD6-6576M Recombinant Mouse PDCD6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Pdcd6-4735M Recombinant Mouse Pdcd6 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rhesus monkey PDCD6-1824R Recombinant Rhesus Monkey PDCD6 Protein, hIgG1-tagged HEK293 hIgG1
Rhesus monkey PDCD6-1825R Recombinant Rhesus Monkey PDCD6 Protein, hIgG4-tagged HEK293 hIgG4
Cynomolgus Monkey PDCD6-776C Recombinant Cynomolgus PDCD6 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey PDCD6-520C Recombinant Cynomolgus Monkey PDCD6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey PDCD6-520C-B Recombinant Cynomolgus Monkey PDCD6 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish PDCD6-11187Z Recombinant Zebrafish PDCD6 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PDCD6 Related Research Area

PDCD6 involved in several pathways and played different roles in them. We selected most pathways PDCD6 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PDCD6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

PDCD6 has several biochemical functions, for example, binding, bridging, calcium ion binding, calcium-dependent cysteine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PDCD6 itself. We selected most functions PDCD6 had, and list some proteins which have the same functions with PDCD6. You can find most of the proteins on our site.

Function Related Protein
binding, bridgingTRADD;PDCD6;GAS6
calcium ion bindingSLC25A12;CRNN;LDLR;MYL10;CANX;RET;ANXA7;MMP30;SNCB
calcium-dependent cysteine-type endopeptidase activityGCA;CAPN9;CAPN2L;PEF1;CAPN1A;CAPN3B;CAPN3;CAPN13;CAPN5A
calcium-dependent protein bindingANXA1;RBM22;S100P;RAC3;C9orf9;CALM2;ANXA6;MYO1D;CALM3
identical protein bindingTRIM5;SHMT2;SNX16;CCDC109A;STIM1;ALDOB;FADD;IL12B;TRIM55
protein anchorAKAP6;SLC4A1;RAPSN;SUN5;CIB1;SUN1;NUP153;ALG14;MYH9
protein bindingEPM2AIP1;ERP44;TRAIP;MAP1LC3C;TRAF2;STAR;PPP3CB;TRIM59;STAU1
protein dimerization activityGRIN2A;MYCN;AHR2;MTOR;MYCH;GPR139;SREBF1;ANO7;EBF3A
protein homodimerization activityCCBL1;LRRK2;STK10;IRAK2;COQ9;TCF12;ZNF174;AP1S2;APOA1BP

PDCD6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDCD6 here. Most of them are supplied by our site. Hope this information will be useful for your research of PDCD6.

PEF1; PDCD6IP; PLSCR3

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