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Official Full Name programmed cell death 6
Background This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant.
Synonyms PDCD6; programmed cell death 6; programmed cell death protein 6; ALG 2; apoptosis linked gene 2; PEF1B; apoptosis-linked gene-2; apoptosis-linked gene 2 protein; probable calcium-binding protein ALG-2; ALG-2; MGC9123; FLJ46208; MGC111017; MGC119050
    • Species :
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rhesus monkey
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • GST
    • hIgG1
    • hIgG4
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PDCD6-2556H Recombinant Human PDCD6 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Pdcd6-4735M Recombinant Mouse Pdcd6 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human PDCD6-1595H Recombinant Human PDCD6, GST-tagged E.coli GST
    Human PDCD6-3359HCL Recombinant Human PDCD6 293 Cell Lysate HEK293 N/A
    Human PDCD6-3427H Recombinant Human PDCD6 protein, His-tagged E.coli His
    Mouse PDCD6-12537M Recombinant Mouse PDCD6 Protein Mammalian Cell His
    Cynomolgus Monkey PDCD6-776C Recombinant Cynomolgus PDCD6 Protein, His-tagged Mammalian Cell His
    Rhesus monkey PDCD6-1824R Recombinant Rhesus Monkey PDCD6 Protein, hIgG1-tagged HEK293 hIgG1
    Rhesus monkey PDCD6-1825R Recombinant Rhesus Monkey PDCD6 Protein, hIgG4-tagged HEK293 hIgG4
    Zebrafish PDCD6-11187Z Recombinant Zebrafish PDCD6 Mammalian Cell His

    pdcd6 involved in several pathways and played different roles in them. We selected most pathways pdcd6 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with pdcd6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    pdcd6 has several biochemical functions, for example, binding, bridging, calcium ion binding, calcium-dependent cysteine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by pdcd6 itself. We selected most functions pdcd6 had, and list some proteins which have the same functions with pdcd6. You can find most of the proteins on our site.

    Function Related Protein
    binding, bridging TRADD; GAS6; PDCD6
    calcium ion binding NCALDA; EMR1; PCDH2G4; SVEP1; LPCAT1; AP1S2; MYL10; EPD; DLL1; PCDHGC5
    calcium-dependent cysteine-type endopeptidase activity SRI; CAPN12; GCA; PEF1; CAPN2B; CAPN2L; CAPN3A; CAPN10; CAPN1; CAPN1A
    calcium-dependent protein binding CHP1; VLDLR; S100A6; KCNIP3; ANXA3; FCN2; ANXA4; C9orf9; MYO1D; CD209A
    identical protein binding SMAD1; ERN1; PARK2; KCNJ2; TYSND1; HTT; PARP1; UBQLN4; EED; VWA1
    protein anchor SUN1; SUN5; MYH9; SLC4A1; PDCD6; CIB1; NUP153; AKAP6; ALG14; SUN3
    protein binding NUDCD3; P4HA2; PCGF3; ICAM5; DCLRE1B; VTI1B; GOLSYN; DZIP3; MAGOHB; ARAP3
    protein dimerization activity ARNTL2; ZBED4; HIF1AB; AHR; HER7; MYCS; MEF2B; ARNTL; STK4; PEX3
    protein homodimerization activity NETO2; SRM; ACAT1; TENM3; KIF20B; MSH2; MYPOP; MAPK4; HOMER2; DMRT2

    pdcd6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with pdcd6 here. Most of them are supplied by our site. Hope this information will be useful for your research of pdcd6.


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