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PROC

  • Official Full Name

    protein C (inactivator of coagulation factors Va and VIIIa)

  • Overview

    Protein?C, also known as autoprothrombin IIA and blood coagulation factor XIV, is a zymogenic (inactive) protein, the activated form of which plays an important role in regulating blood clotting, inflammation, cell death and maintaining the permeability of blood vessel walls in humans and other animals. Activated protein?C (APC) performs these operations primarily by proteolytically inactivating proteins Factor Va and Factor VIIIa. APC is classified as a serine protease, as it contains a residue of serine in its active site. In humans, protein?C is encoded by the PROC gene, which is found on chromosome 2
  • Synonyms

    PROC; PROC1; PC; APC; vitamin K-dependent protein C; EC 3.4.21; OTTHUMP00000203820; OTTHUMP00000203827; Blood coagulation factor XIV; Autoprothrombin IIA; Anticoagulant protein C protein C (inactivator of coagulation factors Va and VIIIa); Activation peptide; Anticoagulant protein C; APC; Autoprothrombin IIA; Blood coagulation factor XIV; PC; proC; PROC_HUMAN; PROC1; Protein C (inactivator of coagulation factors Va and VIIIa); THPH3; THPH4; Vitamin K dependent protein C; Protein C;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Therapeutic Proteins
  • Native Proteins
  • Transfected Stable Cell Lines
  • Protein Pre-coupled Magnetic Beads
  • Bovine
  • Chicken
  • Human
  • Mouse
  • Mycobacterium tuberculosis
  • Rat
  • CHO
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • Human Plasma
  • Mammalian Cell
  • Mammalian cells
  • Mouse Plasma
  • Plasma
  • Yeast
  • C
  • His
  • Flag
  • His (Fc)
  • Avi
  • Myc
  • His|GST
  • DDK
  • Myc|DDK
  • N/A
  • N
  • SUMO
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PROC-25H Active Recombinant Human PROC protein, His-tagged CHO His
Human PROC-24H Active Recombinant Human PROC protein, His-tagged Mammalian cells His
Human PROC-59H Recombinant Human PROC, His-tagged HEK293 His
Human PROC-194H Recombinant Human PROC Protein, His-tagged HEK293 His Met1-Pro461
Human PROC-33H Recombinant Human PROC protein, His-tagged E.coli His Ser53~Ile445
Human PROC-32H Recombinant Human PROC CHO N/A
Human PROC-852HCL Recombinant Human PROC cell lysate Human Cell N/A
Human PROC-P027H Recombinant Human PROC therapeutic protein N/A
Human PROC-64H Active Native Human Activated Protein C Human Plasma N/A
Human PROC-1743HFL Recombinant Full Length Human PROC Protein, C-Flag-tagged Mammalian cells Flag
Human PROC-176H Human Protein C (Plasma) Reference standard N/A
Human PROC-1772H-B Recombinant Human PROC Protein Pre-coupled Magnetic Beads HEK293
Human PROC-3000H Recombinant Human PROC Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human PROC-6008H Recombinant Human PROC Protein (Met1-Pro461), C-His tagged Mammalian cells C-His Met1-Pro461
Human PROC-3505H Recombinant Human PROC Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PROC-2537H Recombinant Human PROC protein(51-190 aa), N-SUMO & C-His-tagged E. coli N-SUMO & C-His 51-190 aa
Human PROC-1772H Recombinant Human PROC Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human PROC-6007H Recombinant Human PROC Protein (Thr19-Pro461), C-His tagged Mammalian cells C-His Thr19-Pro461
Mouse Proc-26M Active Recombinant Mouse Proc protein, His-tagged CHO His
Mouse Proc-527M Recombinant Mouse Proc protein, His-tagged HEK293 His Met1-Leu460
Mouse Proc-826M Recombinant Mouse Proc protein, His & GST-tagged E.coli His/GST Lys197~Lys436 (Accession # P33587)
Mouse PROC-747MCL Recombinant Mouse PROC cell lysate Human Cell N/A
Mouse Proc-5346M Native Mouse Protein C Mouse Plasma N/A
Mouse Proc-5137M Recombinant Mouse Proc Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat Proc-827R Recombinant Rat Proc protein, His & GST-tagged E.coli His/GST Trp186~Lys437 (Accession # P31394)
Rat PROC-4709R Recombinant Rat PROC Protein Mammalian Cell His
Rat PROC-4368R-B Recombinant Rat PROC Protein Pre-coupled Magnetic Beads HEK293
Rat PROC-2432R Recombinant Rat PROC Protein (42-461 aa), His-tagged Yeast His 42-461 aa
Rat PROC-4368R Recombinant Rat PROC Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Bovine PROC-273B Active Native Bovine Protein C - DEGR (active site blocked) Plasma N/A
Bovine PROC-272B Active Native Bovine Activated Protein C Plasma N/A
Bovine PROC-269B Active Native Bovine Protein C Plasma N/A
Mycobacterium tuberculosis proC-1390M Recombinant Mycobacterium tuberculosis proC protein, His&Myc-tagged E.coli His&Myc 1-295aa
Chicken PROC-6011C Recombinant Chicken PROC Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PROC Related Articles

PROC involved in several pathways and played different roles in them. We selected most pathways PROC participated on our site, such as Complement and coagulation cascades, which may be useful for your reference. Also, other proteins which involved in the same pathway with PROC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Complement and coagulation cascadesC8G;F13A1;C1QC;CFD;C1R;F3;CD59A;C9;Serpina1c

PROC has several biochemical functions, for example, calcium ion binding, protein binding, serine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PROC itself. We selected most functions PROC had, and list some proteins which have the same functions with PROC. You can find most of the proteins on our site.

Function Related Protein
calcium ion bindingSYT17;DOC2B;TTYH1;LCP1;TPO;CDH3;SLC24A5;PCDH1G26;PPEF2
protein bindingMYO7A;CHD;EIF4A2;B4GALT7;RAD9A;RUVBL1;NLRP2;PRMT6;ZBED4
serine-type endopeptidase activityHTRA4;TMPRSS3;ST14A;FURINB;PARL;GZMC;KLK1;PRSS21;HTRA3A

PROC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PROC here. Most of them are supplied by our site. Hope this information will be useful for your research of PROC.

MMP15; TK1; CSNK2B

Dall'Aglio, M; Di Luca, C; et al. Bounds for alpha-optimal partitioning of a measurable space based on several efficient partitions. JOURNAL OF MATHEMATICAL ANALYSIS AND APPLICATIONS 425:854-863(2015).
Gomes, GMS; Santa-Clara, C; et al. The semigroup ring of a restriction semigroup with an inverse skeleton. SEMIGROUP FORUM 90:449-474(2015).
  • Q&As
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