Recombinant Full Length Human PROC Protein, C-Flag-tagged
Cat.No. : | PROC-1743HFL |
Product Overview : | Recombinant Full Length Human PROC Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 50 kDa |
AA Sequence : | MWQLTSLLLFVATWGISGTPAPLDS VFSSSERAHQVLRIRKRANSFLEEL RHSSLERECIEEICDFEEAK EIFQNVDDTLAFWSKHVDGDQCLVL PLEHPCASLCCGHGTCIDGIGSFSC DCRSGWEGRFCQREVSFLNC SLDNGGCTHYCLEEVGWRRCSCAPG YKLGDDLLQCHPAVKFPCGRPWKRM EKKRSHLKRDTEDQEDQVDP RLIDGKMTRRGDSPWQVVLLDSKKK LACGAVLIHPSWVLTAAHCMDESKK LLVRLGEYDLRRWEKWELDL DIKEVFVHPNYSKSTTDNDIALLHL AQPATLSQTIVPICLPDSGLAEREL NQAGQETLVTGWGYHSSREK EAKRNRTFVLNFIKIPVVPHNECSE VMSNMVSENMLCAGILGDRQDACEG DSGGPMVASFHGTWFLVGLV SWGEGCGLLHNYGVYTKVSRYLDWI HGHIRDKEAPQKSWAPTRTRPLEQK LISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome, Protease |
Protein Pathways : | Complement and coagulation cascades |
Gene Name : | PROC protein C, inactivator of coagulation factors Va and VIIIa [ Homo sapiens (human) ] |
Official Symbol : | PROC |
Synonyms : | PC; APC; PROC1; THPH3; THPH4 |
Gene ID : | 5624 |
mRNA Refseq : | NM_000312.4 |
Protein Refseq : | NP_000303.1 |
MIM : | 612283 |
UniProt ID : | P04070 |
Products Types
◆ Recombinant Protein | ||
PROC-3000H | Recombinant Human PROC Protein, MYC/DDK-tagged | +Inquiry |
Proc-5137M | Recombinant Mouse Proc Protein, Myc/DDK-tagged | +Inquiry |
PROC-1772H | Recombinant Human PROC Protein, His (Fc)-Avi-tagged | +Inquiry |
PROC-2432R | Recombinant Rat PROC Protein (42-461 aa), His-tagged | +Inquiry |
PROC-2537H | Recombinant Human PROC protein(51-190 aa), N-SUMO & C-His-tagged | +Inquiry |
◆ Native Protein | ||
Proc-5346M | Native Mouse Protein C | +Inquiry |
PROC-269B | Active Native Bovine Protein C | +Inquiry |
PROC-273B | Active Native Bovine Protein C - DEGR (active site blocked) | +Inquiry |
◆ Lysates | ||
PROC-747MCL | Recombinant Mouse PROC cell lysate | +Inquiry |
PROC-852HCL | Recombinant Human PROC cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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