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PTPRS

  • Official Full Name

    protein tyrosine phosphatase, receptor type, S

  • Overview

    The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. This PTP has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.
  • Synonyms

    PTPRS; protein tyrosine phosphatase, receptor type, S; receptor-type tyrosine-protein phosphatase S; R-PTP-S; R-PTP-sigma; protein tyrosine phosphatase PTPsigma; receptor-type tyrosine-protein phosphatase sigma; protein tyrosine phosphatase, receptor type;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • His|T7
  • DDK
  • MYC
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PTPRS-808H Active Recombinant Human PTPRS Protein, His-tagged Mammalian cells His Glu30-Gly1260
Human PTPRS-1525H Active Recombinant Human PTPRS, GST-tagged E.coli GST 883-1210 aa
Human PTPRS-6776H Recombinant Human PTPRS protein, His & T7-tagged E.coli His/T7 Arg77~Gly361 (Accession # Q13332)
Human PTPRS-31118TH Recombinant Human PTPRS E.coli N/A
Human PTPRS-31119TH Recombinant Human PTPRS E.coli N/A
Human PTPRS-470H Recombinant Human PTPRS, GST-tagged, Active E.coli GST
Human PTPRS-2670HCL Recombinant Human PTPRS 293 Cell Lysate HEK293 N/A
Human PTPRS-4145H Recombinant Human PTPRS Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PTPRS-5158H Recombinant Human PTPRS Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PTPRS-301632H Recombinant Human PTPRS protein, GST-tagged E.coli GST Gly25-Pro128
Human PTPRS-2766H Recombinant Human PTPRS Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PTPRS-3948H Recombinant Human PTPRS Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human PTPRS-301542H Recombinant Human PTPRS protein, GST-tagged E.coli GST Val825-Leu1000
Human PTPRS-3948H-B Recombinant Human PTPRS Protein Pre-coupled Magnetic Beads HEK293
Human PTPRS-6113H Recombinant Human PTPRS Protein (Arg77-Gly374), N-His tagged E.coli N-His Arg77-Gly374
Mouse PTPRS-13707M Recombinant Mouse Ptprs Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse Ptprs-6777M Recombinant Mouse Ptprs protein, His & T7-tagged E.coli His/T7 Arg889~His1102 (Accession # B0V2N1)
Mouse Ptprs-4509M Recombinant Mouse Ptprs protein, His&Myc-tagged Insect Cell His&Myc 1631-1907aa
Mouse Ptprs-5252M Recombinant Mouse Ptprs Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Ptprs-4510M Recombinant Mouse Ptprs protein, His&Myc-tagged E.coli His&Myc 1631-1907aa
Rat PTPRS-4845R Recombinant Rat PTPRS Protein Mammalian Cell His
Rat PTPRS-4504R Recombinant Rat PTPRS Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PTPRS-4504R-B Recombinant Rat PTPRS Protein Pre-coupled Magnetic Beads HEK293
Chicken PTPRS-6958C Recombinant Chicken PTPRS Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

PTPRS involved in several pathways and played different roles in them. We selected most pathways PTPRS participated on our site, such as ECM proteoglycans, Extracellular matrix organization, which may be useful for your reference. Also, other proteins which involved in the same pathway with PTPRS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
ECM proteoglycansCOL9A3;ASPN;VCANB;FMOD;MATN4;MATN3B;DAG1;MUSK;BGNA
Extracellular matrix organizationFBN1;DMD;MMP19;MFAP2;COL15A1B;FURINB;KLK7;LOXL3;COL19A1

PTPRS has several biochemical functions, for example, protein binding, transmembrane receptor protein tyrosine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PTPRS itself. We selected most functions PTPRS had, and list some proteins which have the same functions with PTPRS. You can find most of the proteins on our site.

Function Related Protein
protein bindingMASP1;GLUD1;ATG5;COPS5;SID4;RPH3A;FAM19A1;CD37;ZC3HC1
transmembrane receptor protein tyrosine phosphatase activityPTPRN2;PTPRB;PTPRUB;PTPRG;PTPRS;PTPRA;PTPRF;PTPRC;EVLA

PTPRS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PTPRS here. Most of them are supplied by our site. Hope this information will be useful for your research of PTPRS.

PTPRN; EIF4A2; PTN; EEF1G; PFN2; SUMO2; CHD3; UNC119; TUBB2A; SETDB1; RAB35; UBR1; KAT5; FEZ1; UTP14A; CEP126

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