Active Recombinant Human PTPRS Protein, His-tagged

• Cat.No.: PTPRS-808H
• Product Overview: Recombinant Human PTPRS (Accession # NP_570924) Glu30-Gly1260, fused with a C-terminal 6-His tag, was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Source: Mammalian cells
• Species: Human
• Tag: His
• Predicted N Terminal: Glu30 & Ser1173
• Form: Lyophilized from a 0.2 µm filtered solution in HEPES and NaCl.
• Bio-activity: Measured by its binding ability in a functional ELISA.When Recombinant Human PTPR sigma/PTPRS is coated at 2 µg/mL, Recombinant Human TrkC Fc Chimera binds with an apparent Kd <1 nM.
• Molecular Mass: Recombinant Human PTPRS, His-tagged has a calculated MW of 135.8 kDa. In SDS-PAGE migrates as 120-145 kDa, reducing conditions.
• Protein length: Glu30-Gly1260
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
• Reconstitution: Reconstitute at 10 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
• Publication:
  CSPG-PTPσ blockade promote neurofilament growth and synaptic formation via regulating autophagy flux in spinal cord injury (2023)

Gene Information

• Gene Name: PTPRS protein tyrosine phosphatase, receptor type, S [ Homo sapiens ]
• Official Symbol: PTPRS
• Synonyms: PTPRS; protein tyrosine phosphatase, receptor type, S; receptor-type tyrosine-protein phosphatase S; R-PTP-S; R-PTP-sigma; protein tyrosine phosphatase PTPsigma; receptor-type tyrosine-protein phosphatase sigma; protein tyrosine phosphatase, receptor type, sigma; PTPSIGMA
• Gene ID: 5802
• mRNA Refseq: NM_002850
• Protein Refseq: NP_002841
• MIM: 601576
• UniProt ID: Q13332
• Chromosome Location: 19p13.3