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RCVRN

  • Official Full Name

    recoverin

  • Overview

    This gene encodes a member of the recoverin family of neuronal calcium sensors. The encoded protein contains three;calcium-binding EF-hand domains and may prolong the termination of the phototransduction cascade in the retina by;blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for;cancer-associated retinopathy.
  • Synonyms

    RCVRN; recoverin; RCV1; cancer associated retinopathy antigen; cancer-associated retinopathy protein;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Yeast
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • His|Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human RCVRN-2233H Recombinant Human RCVRN, GST-tagged E.coli GST 7-166AA
Human RCVRN-191H Recombinant Human Recoverin E.coli N/A
Human RCVRN-31310TH Recombinant Human RCVRN E.coli N/A
Human RCVRN-2442HCL Recombinant Human RCVRN 293 Cell Lysate HEK293 N/A
Human RCVRN-2765H Recombinant Human RCVRN Protein (2-200 aa), His-Myc-tagged Insect Cell His/Myc 2-200 aa
Human RCVRN-5057H Recombinant Human RCVRN protein, His&Myc-tagged HEK293 His&Myc 2-200aa
Human RCVRN-1870H-B Recombinant Human RCVRN Protein Pre-coupled Magnetic Beads HEK293
Human RCVRN-250H Recombinant Human RCVRN Protein, His-tagged E.coli His Gly2~Ala200
Human RCVRN-1847H Recombinant Human RCVRN Protein (2-200 aa), His-tagged Yeast His 2-200 aa
Human RCVRN-22H Recombinant Human RCVRN Protein, Myc/DDK-tagged HEK293T Myc/DDK
Human RCVRN-14H Recombinant Human RCVRN Protein, GST-tagged Wheat Germ GST
Human RCVRN-1037HFL Recombinant Full Length Human RCVRN Protein, C-Flag-tagged Mammalian cells Flag
Human RCVRN-1870H Recombinant Human RCVRN Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human RCVRN-6160H Recombinant Human RCVRN Protein (Gly2-Ala200), His tagged E.coli His Gly2-Ala200
Mouse Rcvrn-001M Recombinant Mouse Rcvrn Protein, His-tagged E.coli His
Mouse Rcvrn-5441M Recombinant Mouse Rcvrn Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rhesus Macaque RCVRN-3835R Recombinant Rhesus monkey RCVRN Protein, His-tagged Mammalian Cell His
Rhesus Macaque RCVRN-3652R-B Recombinant Rhesus Macaque RCVRN Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque RCVRN-3652R Recombinant Rhesus Macaque RCVRN Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • RCVRN Related Articles

RCVRN involved in several pathways and played different roles in them. We selected most pathways RCVRN participated on our site, such as Phototransduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with RCVRN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
PhototransductionCALM2B;CALM3;GNAT1;GC3;RGS9;CALM3A;GNB4B;SAG;GNB1B

RCVRN has several biochemical functions, for example, calcium ion binding, calcium sensitive guanylate cyclase activator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RCVRN itself. We selected most functions RCVRN had, and list some proteins which have the same functions with RCVRN. You can find most of the proteins on our site.

Function Related Protein
calcium ion bindingCIB3;PRF1;STIM1;GUCA1G;SPTA1;NECAB2;JAG2B;PCDH2AB1;SLC25A25
calcium sensitive guanylate cyclase activator activityGUCA1D;RCVRN;GUCA1B;GUCA2B;GUCA1G;GUCA1E;GUCA1C;GUCA1A

RCVRN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RCVRN here. Most of them are supplied by our site. Hope this information will be useful for your research of RCVRN.

PQBP1; TGFBR2; SMAD3; IL15RA; GIT2

Butz, E; Peichl, L; et al. Cone Bipolar Cells in the Retina of the Microbat Carollia perspicillata. JOURNAL OF COMPARATIVE NEUROLOGY 523:963-981(2015).
Kitai, H; Sakakibara-Konishi, J; et al. Spontaneous regression of small cell lung cancer combined with cancer associated retinopathy. LUNG CANCER 87:73-76(2015).
  • Q&As
  • Reviews

Q&As (5)

Ask a question
Are there any specific populations that may benefit more from RCVRN-targeted therapies? 03/02/2022

Individuals with genetic mutations affecting RCVRN and those with early-stage retinal diseases may potentially benefit more from targeted therapies.

How does the expression of RCVRN change with age, and does this have implications for age-related vision disorders? 10/29/2021

The expression of RCVRN may change with age, and understanding these changes can provide insights into age-related vision disorders.

How is the level of RCVRN expression correlated with the progression of certain retinal disorders? 01/22/2021

Changes in RCVRN expression levels may correlate with the progression of retinal disorders, serving as a potential indicator of disease severity.

Are there ongoing clinical trials exploring the use of RCVRN-based therapies? 02/11/2017

Some clinical trials are investigating the safety and efficacy of gene therapies targeting the RCVRN gene for treating specific eye conditions.

How might the manipulation of RCVRN expression offer therapeutic benefits for patients with vision impairments? 03/04/2016

Modulating RCVRN expression could potentially restore or enhance photoreceptor function, providing therapeutic benefits for vision-impaired individuals.

Customer Reviews (3)

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Reviews
02/16/2020

    Whether investigating metabolic pathways, studying enzymatic activity, or exploring drug targets, this protein offers versatility and reliability, allowing for accurate and meaningful data collection.

    05/29/2018

      In addition to the remarkable protein quality, the manufacturer provides excellent technical support, proving to be a valuable resource when troubleshooting experimental challenges.

      06/24/2016

        Incorporating this protein into scientific investigations undoubtedly enhances the reliability and effectiveness of research endeavors.

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