Recombinant Mouse Rcvrn Protein, His-tagged
Cat.No. : | Rcvrn-001M |
Product Overview : | Recombinant Mouse recoverin(33-293aa), fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
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Description : | Recoverin also known as Rcvrn, is a heterogeneously acylated calcium-binding and intracellular signal transduction protein in the photoreceptor cells of retina. Recoverin contains four EF-hands, of which two bind Ca. Ca-induced extrusion of the acyl group from a hydrophobic cleft in the protein drives the translocation of recoverin from solution to the disc membrane. Recently, recoverin is a detectable serologic protein that is expressed in patients with cancer-associated retinopathy, a paraneoplastic syndrome. |
Source : | E.coli |
Species : | Mouse |
Tag : | His |
Form : | Liquid |
Molecular Mass : | 25.8 kDa |
AASequence : | MGSSHHHHHHSSGLVPRGSHMGSMG NSKSGALSKEILEELQLNTKFTEEE LSAWYQSFLKECPSGRITRQEFESI YSKFFPDSDPKAYAQHVFRSFDANS DGTLDFKEYVIALHMTTAGKPTQKL EWAFSLYDVDGNGTISKNEVLEIVM AIFKMIKPEDVKLLPDDENTPEKRA EKIWAFFGKKEDDKLTEEEFIEGTL ANKEILRLIQFEPQKVKERIKEKKQ |
Purity : | > 90% by SDS - PAGE |
Storage : | Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 1.0 mg/mL (determined by Absorbance at 280nm) |
Storage Buffer : | In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. 1mM DTT. |
Warning : | For research use only. This product is not intended or approved for human, diagnostics or veterin |
Gene Name : | Rcvrn recoverin [ Mus musculus (house mouse) ] |
Official Symbol : | Rcvrn |
Synonyms : | CAR; S-modulin; recoverin; 23 kDa photoreceptor cell-specific protein; cancer-associated retinopathy protein; guanylate cyclase activator |
Gene ID : | 19674 |
mRNA Refseq : | NM_009038 |
Protein Refseq : | NP_033064 |
UniProt ID : | P34057 |
Products Types
◆ Recombinant Protein | ||
RCVRN-250H | Recombinant Human RCVRN Protein, His-tagged | +Inquiry |
RCVRN-14H | Recombinant Human RCVRN Protein, GST-tagged | +Inquiry |
RCVRN-3652R | Recombinant Rhesus Macaque RCVRN Protein, His (Fc)-Avi-tagged | +Inquiry |
RCVRN-2765H | Recombinant Human RCVRN Protein (2-200 aa), His-Myc-tagged | +Inquiry |
RCVRN-22H | Recombinant Human RCVRN Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
RCVRN-2442HCL | Recombinant Human RCVRN 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionIndividuals with genetic mutations affecting RCVRN and those with early-stage retinal diseases may potentially benefit more from targeted therapies.
The expression of RCVRN may change with age, and understanding these changes can provide insights into age-related vision disorders.
Changes in RCVRN expression levels may correlate with the progression of retinal disorders, serving as a potential indicator of disease severity.
Some clinical trials are investigating the safety and efficacy of gene therapies targeting the RCVRN gene for treating specific eye conditions.
Modulating RCVRN expression could potentially restore or enhance photoreceptor function, providing therapeutic benefits for vision-impaired individuals.
Customer Reviews (3)
Write a reviewWhether investigating metabolic pathways, studying enzymatic activity, or exploring drug targets, this protein offers versatility and reliability, allowing for accurate and meaningful data collection.
In addition to the remarkable protein quality, the manufacturer provides excellent technical support, proving to be a valuable resource when troubleshooting experimental challenges.
Incorporating this protein into scientific investigations undoubtedly enhances the reliability and effectiveness of research endeavors.
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