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Official Full Name ring finger protein 2
Background The polycomb group (PcG) proteins contribute to the maintenance of cell identity, stem cell self-renewal, cell-cycle regulation, and oncogenesis by maintaining the silenced state of genes that promote cell lineage specification, cell death, and cell-cycle
Synonyms RNF2; ring finger protein 2; E3 ubiquitin-protein ligase RING2; BAP 1; BAP1; DING; HIPI3; RING1B; RING2; protein DinG; RING finger protein 1B; RING finger protein BAP-1; HIP2-interacting protein 3; huntingtin-interacting protein 2-interacting protein 3; B
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human RNF2-158H Recombinant Human RNF2 protein, T7/His-tagged E.coli T7/His
    Human RNF2-2284HCL Recombinant Human RNF2 293 Cell Lysate HEK293 N/A
    Human RNF2-2341H Recombinant Human RNF2, GST-tagged E.coli GST
    Human RNF2-5035H Recombinant Human RNF2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human RNF2-695H Recombinant Human RNF2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Mouse Rnf2-5554M Recombinant Mouse Rnf2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Rat RNF2-5080R Recombinant Rat RNF2 Protein Mammalian Cell His
    Zebrafish RNF2-8814Z Recombinant Zebrafish RNF2 Mammalian Cell His

    rnf2 involved in several pathways and played different roles in them. We selected most pathways rnf2 participated on our site, such as Cellular Senescence, Cellular responses to stress, Metabolism of proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with rnf2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cellular Senescence HIST1H1D; MAPKAPK2B; UBN1; HIST1H1E; HMGA1B; E2F2; CDKN2B; EP400; CBX8B; EED
    Cellular responses to stress HIST2H3C; HDAC6; IGFBP7; KIAA1967; BMI1A; BAG3; SUZ12; KAT5; EGLN3; RRAGA
    Metabolism of proteins GALNTL2; B3GNT8; ST6GALNAC2; DPH2; ZDHHC2; GRPEL1; CNIH2; SENP5; TBCB; SERPINA7
    Oxidative Stress Induced Senescence KDM6B; CBX8A; SUZ12A; SUZ12; EED; CBX6A; MINK1; SCMH1; PHC2; CBX8
    Post-translational protein modification ZNF408; GALNT5; NEU4; MPDU1B; ADAMTS8; PROZ; ADAMTSL3; GALNT6; MUC21; ARSJ
    SUMO E3 ligases SUMOylate target proteins SCMH1; NSMCE4A; CBX8; PHC2; SMC6; PHC3; CBX4; RNF2; NSMCE1; SMC5
    SUMOylation of DNA damage response and repair proteins SCMH1; EID3; RNF2; NSMCE4A; NSMCE2; SMC5; PHC1; NSMCE1; PHC3; CBX8

    rnf2 has several biochemical functions, for example, RING-like zinc finger domain binding, chromatin binding, ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by rnf2 itself. We selected most functions rnf2 had, and list some proteins which have the same functions with rnf2. You can find most of the proteins on our site.

    Function Related Protein
    RING-like zinc finger domain binding UBE2I; BMI1; RNF2
    chromatin binding CDK9; MCM5; CBX4; MB21D2; TADA2A; MBD1; YAP1; NEUROD1; SIX1; RERE
    ligase activity UBR5; BRAP; MKRN3; TTLL2; BARD1; RNF138; DZIP3; TRIM9; RNF146; RNF185
    protein binding FBXO4; CD99L2; AIM2; IFI6; KCNA4; CCS; MOCOS; IPO7; GTF2H1; PSMB5
    ubiquitin protein ligase activity G2E3; MED20; UBE2G1A; LTN1; HUWE1; MARCH1; NEURL3; MED27; HERC6; RNF152
    contributes_to ubiquitin-protein transferase activity KEAP1A; FBXW8; KCTD13; KLHL5; BACH1; FBXL15; KLHL12; GAN; KLHL1; UBE2S
    zinc ion binding PHF23A; ZCCHC8; NR2F1; BTR16; NR2E3; MLLT6; Ar; Shh; CPA6; ADAM8A

    rnf2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with rnf2 here. Most of them are supplied by our site. Hope this information will be useful for your research of rnf2.

    BMI1; CBX8; PCGF2

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