RNF4

  • Official Full Name

    ring finger protein 4
  • Synonyms

    RNF4;ring finger protein 4;SLX5;SNURF;RES4-26;E3 ubiquitin-protein ligase RNF4;E3 ubiquitin ligase RNF4;small nuclear RING finger protein;EC=6.3.2;Protein SNURF;002938

Recombinant Proteins

  • Mouse
  • Chicken
  • Rat
  • Human
  • Mammalian Cells
  • E.coli
  • HEK293
  • His
  • Non
  • GST
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
RNF4-14347M Recombinant Mouse RNF4 Protein Mammalian Cells Mouse His
RNF4-2104C Recombinant Chicken RNF4 Mammalian Cells Chicken His
RNF4-5083R Recombinant Rat RNF4 Protein Mammalian Cells Rat His
RNF4-7193H Recombinant Human Ring Finger Protein 4, His-tagged E.coli Human His 1-190aa
RNF4-2276HCL Recombinant Human RNF4 293 Cell Lysate HEK293 Human Non
RNF4-0444H Recombinant Human RNF4 Protein (G120-I190), Tag Free E.coli Human Non G120-I190
RNF4-0445H Recombinant Human RNF4 Protein (G120-I190), GST tagged E.coli Human GST G120-I190
Rnf4-1654M Recombinant Mouse Rnf4 protein, His & GST-tagged E.coli Mouse GST&His Met1~Ile194
RNF4-311H Recombinant Human RNF4 protein, GST-tagged E.coli Human GST 1-190 aa
RNF4-314H Recombinant Human RNF4 Protein, GST-tagged E.coli Human GST
RNF4-4742R Recombinant Rat RNF4 Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
RNF4-4742R-B Recombinant Rat RNF4 Protein Pre-coupled Magnetic Beads HEK293 Rat
RNF4-7685M Recombinant Mouse RNF4 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
RNF4-7685M-B Recombinant Mouse RNF4 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    RNF4 involved in several pathways and played different roles in them. We selected most pathways RNF4 participated on our site, such as Adaptive Immune System,Androgen receptor signaling pathway,Antigen processing: Ubiquitination &amp, which may be useful for your reference. Also, other proteins which involved in the same pathway with RNF4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Androgen receptor signaling pathway CDKN1A,KAT5,POU2F1B,RANBP9,KAT7B,ZMIZ1,CARM1,NR2C2,EGFR,ETV5A
    Class I MHC mediated antigen processing &amp TRAF7,RNF111,FBXO3,UBR2,BLMH,TRIM63,KLHL21,TRIM50,ATG7,FBXO27
    DNA Repair TDP1,WRN,TIPIN,GPS1,RHNO1,ALKBH2,DDB2,CHD1L,TOPBP1,INO80E
    presentation ASB9,SPSB2,UBE2V2,UBE2V1,CTSS,ERAP2,ASB2,TRIM50,CTSL2,CYBB
    DNA Double-Strand Break Repair EME1,TOPBP1,SMARCA5,CHEK1,DNA2,PPP4R2B,RAD9,BRCC3,KDM4B,BRE
    HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA) WRN,TP53BP1,BABAM1,RTEL1,PPP4CB,BRCC3,TIMELESS,PPP4R2,BRE,RAD1
    Adaptive Immune System LAIR2,RNF220,CTSL2,SIGLEC10,ASB6,RACGAP1,AP2S1,ACTR1B,TRIM9,KIF5A
    Antigen processing: Ubiquitination &amp RNF111,UBE2V1,ASB7,FBXO27,RNF138,TRIM50,UBR2,RNF6,ARIH2,ASB2
    Homology Directed Repair PPP4CB,PPP4CA,EME1,WRN,PPP4R2,KIAA0146,PPP4R2B,GEN1,PPP4R2A,EME2

    Protein Function

    RNF4 has several biochemical functions, for example, DNA binding,SUMO polymer binding,androgen receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RNF4 itself. We selected most functions RNF4 had, and list some proteins which have the same functions with RNF4. You can find most of the proteins on our site.

    Function Related Protein
    androgen receptor binding DAXX,PIAS2,NCOA3,NCOA4,FOXH1,PARK7,KDM4C,RB1,SMARCA4,RAN
    ubiquitin-protein transferase activity CBLB,FBXO30B,UBE2D2A,TRIM17,RBBP6,FBXO22,TRIM28,ANKIB1,FBXO7,RNF125
    ligase activity TRIM27,RNF2,RNF19A,SHRPRBCK1R,MGRN1A,HECTD3,RLIM,FPGS,HECW1B,GLULC
    protein binding GLS,POP5,EPHA3,GLI3,C1QTNF3,TULP3,PCNP,SEPSECS,ADAM15,LRFN4
    transcription factor binding NLK,AGTR2,MLXIPL,RNF19A,SLC26A5,PPID,FOXO4,SMAD3,PRKDC,CEBPB
    SUMO polymer binding RNF111,SOBP,SIMC1,RNF222
    nucleosome binding RNF169,DNTTIP1,ZNHIT1,RNF168,SMARCA5,L3MBTL1,HP1BP3,ARID1A,NOC2L,MUM1
    identical protein binding SNX1,ALDH4A1,CD74,CEACAM16,SMAD4,WRNIP1,RYR2,GLUL,PFKM,BCHE
    ubiquitin protein ligase activity TRIM24,MED10,RNF19A,UBE2Z,UBE2J2,UBE2S,MED21,NHLRC1,HECW1B,MSL2B

    Interacting Protein

    RNF4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RNF4 here. Most of them are supplied by our site. Hope this information will be useful for your research of RNF4.

    UBE2I;TRPS1;PARP1;UBA1;UBE2N;SRPK2;UBE2V1;NFATC2IP;HIP2;SKIL;UBE2D1;UBE2E1;UBE2D3;UBE2H;UBE2D2;cdsA

    Resources

    References

    • Hendriks, IA; Treffers, LW; et al. SUMO-2 Orchestrates Chromatin Modifiers in Response to DNA Damage. CELL REPORTS 10:1778-1791(2015).
    • Pagadala, NS; Perez-Pineiro, R; et al. In silico studies and fluorescence binding assays of potential anti-prion compounds reveal an important binding site for prion inhibition from PrPC to PrPSc. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 91:118-131(2015).

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