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Official Full Name ring finger protein 4
Synonyms RNF4;ring finger protein 4;SLX5;SNURF;RES4-26;E3 ubiquitin-protein ligase RNF4;E3 ubiquitin ligase RNF4;small nuclear RING finger protein;EC=6.3.2;Protein SNURF;002938;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E. coli
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human RNF4-311H Recombinant Human RNF4 protein, GST-tagged E. coli GST
    Human RNF4-2276HCL Recombinant Human RNF4 293 Cell Lysate HEK293 N/A
    Human RNF4-314H Recombinant Human RNF4 Protein, GST-tagged E.coli GST
    Human RNF4-7193H Recombinant Human Ring Finger Protein 4, His-tagged E.coli His
    Mouse RNF4-14347M Recombinant Mouse RNF4 Protein Mammalian Cell His
    Mouse Rnf4-1654M Recombinant Mouse Rnf4 protein, His & GST-tagged E.coli His/GST
    Rat RNF4-5083R Recombinant Rat RNF4 Protein Mammalian Cell His
    Chicken RNF4-2104C Recombinant Chicken RNF4 Mammalian Cell His

    RNF4 involved in several pathways and played different roles in them. We selected most pathways RNF4 participated on our site, such as Adaptive Immune System, Androgen receptor signaling pathway, Antigen processing: Ubiquitination &amp, which may be useful for your reference. Also, other proteins which involved in the same pathway with RNF4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System CTSK; RNF144B; KLRF1; SEC61B; AP2A2; MICA; TREM1; KIF3C; TREML1; UBR2
    Androgen receptor signaling pathway POU2F1B; KDM1A; KAT7; SMARCE1; DAXX; NCOA2; JUN; MYST2; CARM1; CDKN1A
    Antigen processing: Ubiquitination &amp UBE2V2; UBE2L6; STUB1; ASB2; TRAF7; ARIH2; UBE2J2; UBE2F; UFL1; RNF14
    Proteasome degradation RNF138; ASB17; RNF123; UBE2V2; TRIM63; LRR1; TRIM41; RNF220; UBE2L6; TRIM39
    Class I MHC mediated antigen processing &amp FBXO3; ASB17; LTN1; PJA1; UBA5; STUB1; BLMH; WWP1; FCGR1B; ATG7
    presentation CMTM2A; B2ML; LRR1; RNF25; TRIM11; RNF34; ASB11; RNF182; DTX3L; TRAF7
    DNA Double-Strand Break Repair PAXIP1; FAM175A; FUZ; TP53BP1; RAD1; CLSPN; BAZ1B; RIF1; BARD1; KDM4A
    DNA Repair UBE2V2; RTEL1; EYA3; PARP2; POLD3; KDM4A; COPS8; SPRTN; KIAA1530; RAD18
    HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA) PPP4R2B; FUZ; TIMELESS; UIMC1; BRE; PPP4R2A; TP53BP1; KIAA0146; GEN1; WRN
    Homology Directed Repair KIAA0146; EME1; PPP4CA; FUZ; PPP4R2; TOPBP1; GEN1; RHNO1; WRN; TIMELESS

    RNF4 has several biochemical functions, for example, DNA binding, SUMO polymer binding, androgen receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RNF4 itself. We selected most functions RNF4 had, and list some proteins which have the same functions with RNF4. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding ATM; MBD1; NPAS4A; HIST1H2BJ; NEUROD6A; ZNF350; ASH1L; THAP11; NR1D1; ZNF621
    SUMO polymer binding SOBP; SIMC1; RNF222; RNF111; RNF4
    androgen receptor binding FOXH1; PKN1; PRMT2; CTNNB1; NCOA4; RNF14; GRIP1; KDM1A; PIAS2; NCOA1
    identical protein binding ADIPOR1; SMN2; SYNE1; BRAP; PTPRM; MID1; ADIPOR2; UGP2; PHC2; ERN1
    ligase activity RNF181; PELI2; TRIM4; TRIM56; RNF220; SMURF2; RNF38; ZNRF1; UBE2G1B; MARCH6
    nucleosome binding HP1BP3; RNF169; L3MBTL1; SMARCA5; ZNHIT1; ARID1A; DNTTIP1; MUM1; RNF168; RNF4
    protein binding NAGK; CARD8; TRIM9; C7orf53; SYMPK; EXOC8; MYL6; RHOXF2; ANXA9; CCDC53
    transcription coactivator activity TFAP2A; NR2F1; NACA; ATF2; CCNE1; SP4; NCOA3; PSMC3; BRD7; MKL1
    transcription factor activity, sequence-specific DNA binding UBN2B; POU2F1B; TTC4; ZEB1; NR2F2; ZNF584; NFIL3-3; ATF4B2; SOX7; FOSL2
    transcription factor binding BRD7; KDM1A; E2F4; PIANP; RBPJ; CEBPG; JUND; TAF7; BCOR; HHEX
    ubiquitin protein ligase activity FBXO6; RAG2; FBXO40; UBR2; COP1; NEDD4; MED24; TRIM59; UBE3C; RNF175
    ubiquitin-protein transferase activity RNF5; TRIM5; BIRC5; UBE2D1; SIAH1A; CBLL1; RNF139; RC3H2; RNF11; RNF144AA
    zinc ion binding ANAPC11; MLL1; PYGO2; PDXK; CA5B; CA3; UBOX5; MSL2B; ZSWIM3; PCGF5A

    RNF4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RNF4 here. Most of them are supplied by our site. Hope this information will be useful for your research of RNF4.


    Hendriks, IA; Treffers, LW; et al. SUMO-2 Orchestrates Chromatin Modifiers in Response to DNA Damage. CELL REPORTS 10:1778-1791(2015).
    Pagadala, NS; Perez-Pineiro, R; et al. In silico studies and fluorescence binding assays of potential anti-prion compounds reveal an important binding site for prion inhibition from PrPC to PrPSc. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 91:118-131(2015).

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