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RPIA

  • Official Full Name

    ribose 5-phosphate isomerase A

  • Overview

    The protein encoded by this gene is an enzyme, which catalyzes the reversible conversion between ribose-5-phosphate and ribulose-5-phosphate in the pentose-phosphate pathway. This gene is highly conserved in most organisms. The enzyme plays an essential role in the carbohydrate metabolism. Mutations in this gene cause ribose 5-phosphate isomerase deficiency. A pseudogene is found on chromosome 18.
  • Synonyms

    RPIA; ribose 5-phosphate isomerase A; ribose-5-phosphate isomerase; ribose 5 phosphate epimerase; EC 5.3.1.6; MGC103524; Phosphoriboisomerase; Ribose 5 phosphate isomerase; ribose 5-phosphate epimerase; RPI; RPIA_HUMAN; zgc:103524;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • E.coli
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cell
  • Yeast
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human RPIA-1571H Recombinant Human Ribose 5-Phosphate Isomerase A, His-tagged E.coli His
Human RPIA-31147TH Recombinant Human RPIA, His-tagged E.coli His
Human RPIA-31148TH Recombinant Human RPIA, His-tagged E.coli His 311 amino acids
Human RPIA-2373H Recombinant Human RPIA, His-tagged E.coli His 1-311aa
Human RPIA-2231HCL Recombinant Human RPIA 293 Cell Lysate HEK293 N/A
Mouse RPIA-14402M Recombinant Mouse RPIA Protein Mammalian Cell His
Mouse RPIA-7719M Recombinant Mouse RPIA Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse RPIA-7719M-B Recombinant Mouse RPIA Protein Pre-coupled Magnetic Beads HEK293
E.coli RPIA-2367E Recombinant Escherichia coli RPIA Protein (1-219 aa) Yeast N/A 1-219 aa
E.coli RPIA-2359E Recombinant Escherichia coli RPIA Protein (1-219 aa), GST-tagged E.coli GST 1-219 aa
Rhesus Macaque RPIA-3968R Recombinant Rhesus monkey RPIA Protein, His-tagged Mammalian Cell His
Rhesus Macaque RPIA-3785R-B Recombinant Rhesus Macaque RPIA Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque RPIA-3785R Recombinant Rhesus Macaque RPIA Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish RPIA-1684Z Recombinant Zebrafish RPIA Mammalian Cell His
Chicken RPIA-2838C Recombinant Chicken RPIA Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • RPIA Related Articles

RPIA involved in several pathways and played different roles in them. We selected most pathways RPIA participated on our site, such as Pentose phosphate pathway, Metabolic pathways, Carbon metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with RPIA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Pentose phosphate pathwayPGM1;PRPS1A;GPI1;PFKP;GPIB;RBKS;TALDO1;FBP2;GPI
Metabolic pathwaysDPYDB;GALNTL1;NDUFA7;HYAL3;MINPP1B;B4GALT1;SGMS1;PTDSS1;NDUFS5
Carbon metabolismSDHDB;ENO1;GM5506;PKMA;CAT;MUT;ACADS;GOT2;GPT2
Biosynthesis of amino acidsENO1B;IDH3B;PRPS1L1;IDH1;TPI1B;PFKL;MAT2AA;CBS;PRPS1B

RPIA has several biochemical functions, for example, monosaccharide binding, protein binding, ribose-5-phosphate isomerase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RPIA itself. We selected most functions RPIA had, and list some proteins which have the same functions with RPIA. You can find most of the proteins on our site.

Function Related Protein
monosaccharide bindingTALDO1;RPIA;GPR19;GPI1;GPI;PGLS;FBP1;Siglece;UPK1A
protein bindingFAM109A;MLH3;RPS6KC1;ZC3H14;CCNB1IP1;NEUROG1;CAMK1;KIF13B;ACTR8
ribose-5-phosphate isomerase activity

RPIA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RPIA here. Most of them are supplied by our site. Hope this information will be useful for your research of RPIA.

STK16; PTPN11; WDYHV1; GORASP2; PCMT1; CENPP

Kaur, PK; Dinesh, N; et al. Identification and characterization of a novel Ribose 5-phosphate isomerase B from Leishmania donovani. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 421:51-56(2012).
  • Q&As
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