The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and altered expression of this protein is associated with the disease cystic fibrosis. [provided by RefSeq, Jul 2008]
S100A9; S100 calcium binding protein A9; MIF; NIF; P14; CAGB; CFAG; CGLB; L1AG; LIAG; MRP14; 60B8AG; MAC387; protein S100-A9; MRP-14; calgranulin B; calgranulin-B; calprotectin L1H subunit; leukocyte L1 complex heavy chain; migration inhibitory factor-related protein 14; S100 calcium-binding protein A9 (calgranulin B);
S100A9 involved in several pathways and played different roles in them. We selected most pathways S100A9 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with S100A9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Related Protein
S100A9 has several biochemical functions, for example, RAGE receptor binding, Toll-like receptor 4 binding, antioxidant activity. Some of the functions are cooperated with other proteins, some of the functions could acted by S100A9 itself. We selected most functions S100A9 had, and list some proteins which have the same functions with S100A9. You can find most of the proteins on our site.
S100A9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with S100A9 here. Most of them are supplied by our site. Hope this information will be useful for your research of S100A9.
S100A8; ARRB2; ARRB1; NOS2; 40031146; NUAK1
Obry, A; Lequerre, T; et al. Identification of S100A9 as Biomarker of Responsiveness to the Methotrexate/Etanercept Combination in Rheumatoid Arthritis Using a Proteomic Approach. PLOS ONE 9:-(2014).
Lapeire, L; Hendrix, A; et al. Cancer-Associated Adipose Tissue Promotes Breast Cancer Progression by Paracrine Oncostatin M and Jak/STAT3 Signaling. CANCER RESEARCH 74:6806-6819(2014).