S100A9
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Official Full Name
S100 calcium binding protein A9
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Overview
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and altered expression of this protein is associated with the disease cystic fibrosis. [provided by RefSeq, Jul 2008] -
Synonyms
S100A9; S100 calcium binding protein A9; MIF; NIF; P14; CAGB; CFAG; CGLB; L1AG; LIAG; MRP14; 60B8AG; MAC387; protein S100-A9; MRP-14; calgranulin B; calgranulin-B; calprotectin L1H subunit; leukocyte L1 complex heavy chain; migration inhibitory factor-related protein 14; S100 calcium-binding protein A9 (calgranulin B);
- Recombinant Proteins
- Native Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Bovine
- Cattle
- Dog
- Human
- Mouse
- Rat
- E.coli
- HEK293
- HEK293 cells
- HEK293T
- Human Cell
- Insect Cell
- Insect Cells
- Mammalian Cell
- Mammalian cells
- Flag
- GST
- His
- Fc
- Avi
- Myc
- B2M
- SUMO
- T7
- DDK
- Non
- StrepII
- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
S100A9 involved in several pathways and played different roles in them. We selected most pathways S100A9 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with S100A9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
S100A9 has several biochemical functions, for example, RAGE receptor binding, Toll-like receptor 4 binding, antioxidant activity. Some of the functions are cooperated with other proteins, some of the functions could acted by S100A9 itself. We selected most functions S100A9 had, and list some proteins which have the same functions with S100A9. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RAGE receptor binding | S100P;S100A4;FPR1;S100A9;S100A8;S100A13;HMGB2;HMGB1;S100A12 |
| Toll-like receptor 4 binding | TIRAP;S100A8;SAA3;S100A9 |
| antioxidant activity | APOA4;UBIAD1;SELS;HP;CAT;MT3;APOE;TRP53INP1;PRDX2 |
| arachidonic acid binding | S100A8;ALOX5AP;CYP4F14;STX3;PPARG;CYP4A14;S100A9 |
| calcium ion binding | KCNIP2;CASQ1A;EHD4;EFHD1;EML1;UMODL1;MYL12.2;RCN1;SLIT1A |
| microtubule binding | KLC3;GABARAP;MTAP1A;JAKMIP2;KIF5A;MID2;NDRG1;KIF9;CCDC88A |
| protein binding | CDH2;BTF3;PALLD;RBM11;TUBA1B;XRCC4;MYOZ1;HIST1H4F;ACCS |
| signal transducer activity | STMN1;MUL1A;RGS9A;OLFCG4;PLCD3A;OLFR482;EDNRBA;MTNR1AL;FPR-RS6 |
| zinc ion binding | SREK1IP1;SCEL;RXRBA;ADAMTS16;SRSF7B;ADH8A;BIRC5;MKRN3;ADH1B |
S100A9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with S100A9 here. Most of them are supplied by our site. Hope this information will be useful for your research of S100A9.
S100A8; ARRB2; ARRB1; NOS2; 40031146; NUAK1
Research Area
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Customer Reviews (3)
Write a reviewThis includes complementary reagents, protocols, and access to an extensive knowledge base, all aimed at streamlining the trial process and maximizing the chances of achieving meaningful results.
By choosing the S100A9 protein and partnering with the manufacturer, researchers can confidently conduct their trials, achieve reliable results, and contribute to groundbreaking discoveries.
Collaborating with the manufacturer opens up possibilities for potential collaboration and exchange of information with a wider scientific community, allowing researchers to stay at the forefront of advancements in their respective fields.
Q&As (5)
Ask a questionS100A9 levels can be measured using various laboratory techniques, such as ELISA (enzyme-linked immunosorbent assay).
Some research is exploring the development of drugs that target S100A9 to modulate inflammation, but clinical applications are still in the experimental phase.
Yes, elevated S100A9 levels have been associated with conditions like rheumatoid arthritis and inflammatory bowel disease, making it a potential biomarker.
Elevated S100A9 levels have been linked to poorer outcomes in certain diseases, making it a potential predictor of disease severity.
Genetic variations can influence S100A9 expression, and these variations may impact an individual's susceptibility to certain diseases.
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