S100A9

  • Official Full Name

    S100 calcium binding protein A9

  • Overview

    The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and altered expression of this protein is associated with the disease cystic fibrosis. [provided by RefSeq, Jul 2008]
  • Synonyms

    S100A9; S100 calcium binding protein A9; MIF; NIF; P14; CAGB; CFAG; CGLB; L1AG; LIAG; MRP14; 60B8AG; MAC387; protein S100-A9; MRP-14; calgranulin B; calgranulin-B; calprotectin L1H subunit; leukocyte L1 complex heavy chain; migration inhibitory factor-related protein 14; S100 calcium-binding protein A9 (calgranulin B);

  • Recombinant Proteins
  • Native Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bovine
  • Cattle
  • Dog
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293 cells
  • HEK293T
  • Human Cell
  • Insect Cell
  • Insect Cells
  • Mammalian Cell
  • Mammalian cells
  • C
  • Myc
  • DDK
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|SUMO
  • His|SUMO|Myc
  • His|T7
  • B2M
  • SUMO
  • Myc|DDK
  • N/A
  • N
  • Strep II
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human S100A9-255H Active Recombinant Human S100A9 protein E.coli N/A
Human S100A9-300H Active Recombinant Human S100A9, His-tagged Insect Cell His
Human S100A9-3179H Native Human S100A9 protein(Met1-Pro114) E.coli N/A Met1-Pro114
Human S100A8 & S100A9-2217H Recombinant Human S100A8 & S100A9 Heterodimer Protein, His & Flag tagged Insect Cells His & Flag Met1-Glu93&Met1-Pro114
Human S100A9-2369H Recombinant Human S100 Calcium Binding Protein A9, His-tagged E.coli His
Human S100A9-3733H Recombinant Human S100A9, His-tagged E.coli His
Human S100A9-433H Recombinant Human S100 Calcium Binding Protein A9 E.coli N/A
Human S100A9-3879H Recombinant Human S100A9, None tagged E.coli N/A
Human S100A9-2215H Active Recombinant Human S100A9, His tagged Insect Cells His Met 1-Pro 114
Human S100A9-295H Recombinant Human S100A9, StrepII-tagged Human Cell Strep II 2-114, 113 a.a.
Human S100A9-684HCL Recombinant Human S100A9 cell lysate Insect Cell N/A
Human S100A9-231H Recombinant Human S100A9 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human S100A9-12HFL Active Recombinant Full Length Human S100A9 Protein, C-Flag-tagged Mammalian cells Flag
Human S100A9-1019H Active Recombinant Human Calprotectin S100A9 Protein E.coli N/A
Human S100A9-233H Recombinant Human S100A9 Protein, His-tagged Insect Cell His
Human S100A9-6221H Recombinant Human S100A9 Protein (Thr2-Pro114), N-His tagged E.coli N-His Thr2-Pro114
Human S100A9-202H Recombinant Human S100A9 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Human S100A9-0051c Recombinant Human S100A9 Protein HEK293 cells
Human S100A9-301159H Recombinant Human S100A9 protein, GST-tagged E.coli GST Lys25-Pro114
Human S100A9-1944H Recombinant Human S100A9 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human S100A9-1944H-B Recombinant Human S100A9 Protein Pre-coupled Magnetic Beads HEK293
Mouse S100A9-3590M Recombinant Mouse S100A9, His-tagged E.coli His
Mouse S100a9-7393M Recombinant Mouse S100a9 protein, His-tagged E.coli His Ala2-Lys113
Mouse S100a9-3466M Recombinant Mouse S100a9 protein, His-SUMO-tagged E.coli His-SUMO 2-113aa
Mouse S100a9-7331M Recombinant Mouse S100a9 Protein, His-tagged E.coli His 1-113
Mouse S100a9-5672M Recombinant Mouse S100a9 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat S100A9-5216R Recombinant Rat S100A9 Protein Mammalian Cell His
Rat S100a9-1806R Recombinant Rat S100a9 protein, His-tagged E.coli His Met1~Lys113 (Accession # P50116)
Rat S100a9-1362H Recombinant Rat S100a9 Protein, His-SUMO-tagged E.coli His/SUMO
Rat S100A9-4875R Recombinant Rat S100A9 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat S100A9-4875R-B Recombinant Rat S100A9 Protein Pre-coupled Magnetic Beads HEK293
Dog S100A9-0223D Recombinant Dog S100A9 Protein, His-tagged E.coli His Met1~His130
Bovine S100A9-2317B Recombinant Bovine S100A9 Protein (2-156 aa), His-SUMO-Myc-tagged E.coli His/SUMO/Myc 2-156 aa
Bovine S100A9-3465B Recombinant Bovine S100A9 protein, His-B2M & Myc-tagged E.coli His-B2M & Myc 2-156aa
Cattle S100A9-1805C Recombinant Cattle S100A9 protein, His & T7-tagged E.coli His/T7 Ile12~Ala89 (Accession # P28783)
Cattle S100A9-1214C Recombinant Cattle S100A9 Protein, His-tagged E.coli N-His Met1-His156
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

S100A9 involved in several pathways and played different roles in them. We selected most pathways S100A9 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with S100A9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

S100A9 has several biochemical functions, for example, RAGE receptor binding, Toll-like receptor 4 binding, antioxidant activity. Some of the functions are cooperated with other proteins, some of the functions could acted by S100A9 itself. We selected most functions S100A9 had, and list some proteins which have the same functions with S100A9. You can find most of the proteins on our site.

Function Related Protein
RAGE receptor bindingFPR1;S100A4;HMGB1;S100A8;S100B;S100A13;S100A9;S100P;S100A12
Toll-like receptor 4 bindingS100A9;SAA3;S100A8;TIRAP
antioxidant activityAPOM;SEPW1;TP53INP1;KDM3B;UBIAD1;FABP1;PRDX6;SELS;PRDX2
arachidonic acid bindingS100A9;CYP4A14;S100A8;ALOX5AP;STX3;PPARG;CYP4F14
calcium ion bindingSYT5A;RHOT2;DLA;ATP2A2;MMP20;EFCAB4B;SYT3;DSG3;MMP1
microtubule bindingJAKMIP2;PAFAH1B1;KIF1C;NDEL1A;HAUS8;KIF18B;GABARAP;UXT;JAKMIP1
protein bindingSNAPIN;GABBR1;CPNE6;NOS1AP;CDH2;TDP2;GBP2;PI4KB;PLAU
signal transducer activitySUFU;OPRD1B;GNAIA;FPR3;OLFCQ19;PLCZ1;DKK1;OLFR502;FLNA
zinc ion bindingZFYVE20;DIDO1;LIMD2;BIRC5;SEC23A;HNF4A;ZCWPW2;PYGO1;RXRAA

S100A9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with S100A9 here. Most of them are supplied by our site. Hope this information will be useful for your research of S100A9.

S100A8; ARRB2; ARRB1; NOS2; 40031146; NUAK1

Research Area

Related articles

Obry, A; Lequerre, T; et al. Identification of S100A9 as Biomarker of Responsiveness to the Methotrexate/Etanercept Combination in Rheumatoid Arthritis Using a Proteomic Approach. PLOS ONE 9:-(2014).
Lapeire, L; Hendrix, A; et al. Cancer-Associated Adipose Tissue Promotes Breast Cancer Progression by Paracrine Oncostatin M and Jak/STAT3 Signaling. CANCER RESEARCH 74:6806-6819(2014).
  • Q&As
  • Reviews

Q&As (5)

Ask a question
How is S100A9 protein measured in clinical settings? 02/05/2019

S100A9 levels can be measured using various laboratory techniques, such as ELISA (enzyme-linked immunosorbent assay).

Are there any therapies or drugs targeting S100A9 in clinical development? 11/13/2018

Some research is exploring the development of drugs that target S100A9 to modulate inflammation, but clinical applications are still in the experimental phase.

Can S100A9 levels be used as a biomarker for specific diseases? 08/26/2017

Yes, elevated S100A9 levels have been associated with conditions like rheumatoid arthritis and inflammatory bowel disease, making it a potential biomarker.

Can S100A9 be used to predict disease outcomes? 02/10/2017

Elevated S100A9 levels have been linked to poorer outcomes in certain diseases, making it a potential predictor of disease severity.

Are there any genetic factors that influence S100A9 levels? 02/29/2016

Genetic variations can influence S100A9 expression, and these variations may impact an individual's susceptibility to certain diseases.

Customer Reviews (3)

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Reviews
08/17/2021

    This includes complementary reagents, protocols, and access to an extensive knowledge base, all aimed at streamlining the trial process and maximizing the chances of achieving meaningful results.

    06/20/2016

      By choosing the S100A9 protein and partnering with the manufacturer, researchers can confidently conduct their trials, achieve reliable results, and contribute to groundbreaking discoveries.

      04/04/2016

        Collaborating with the manufacturer opens up possibilities for potential collaboration and exchange of information with a wider scientific community, allowing researchers to stay at the forefront of advancements in their respective fields.

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