Recombinant Full Length Human S100A9, His-tagged

• Cat.No.: S100A9-3733H
• Product Overview: Total 123 AA. MW: 14.35 kDa (calculated). N-Terminal His-tag, 10 extra AA (highlighted).

Specification

• Cat. No.: S100A9-3733H
• Description: Protein S100-A9 also known as migration inhibitory factor-related protein 14 (MRP-14) or calgranulin-B is a protein that in humans is encoded by the S100A9 gene.
• Source: E. coli
• Species: Human
• Form: Filtered (0,4 μm) and lyophilized in 0.5 mg/mL in 20mM TRIS, 50mM NaCl, PH 7.5
• Reconstitution: Add deionized water to prepare a working stock solution of approximately 0.5 mg/mL and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
• Applications: Western blotting
• Quality Control Test: BCA to determine quantity of the protein; SDS PAGE to determine purity of the protein
• Sequences of amino acids: MKHHHHHHAS TCKMSQLERN IETIINTFHQ YSVKLGHPDT LNQGEFKELV RKDLQNFLKK ENKNEKVIEH IMEDLDTNAD KQLSFEEFIM LMARLTWASH EKMHEGDEGP GHHHKPGLGE GTP
• Storage: Store lyophilized protein at -20°C. Lyophilized protein remains stable until the expiry date when stored at -20°C. Aliquot reconstituted protein to avoid repeated freezing/thawing cycles and store at -80°C for long term storage. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after one week at 4°C.

Gene Information

• Gene Name: S100A9 S100 calcium binding protein A9 [ Homo sapiens ]
• Official Symbol: S100A9
• Synonyms: S100A9; S100 calcium binding protein A9; MIF; NIF; P14; CAGB; CFAG; CGLB; L1AG; LIAG; MRP14; 60B8AG; MAC387; protein S100-A9; MRP-14; calgranulin B; OTTHUMP00000015331; calprotectin L1H subunit; leukocyte L1 complex heavy chain; migration inhibitory factor-related protein 14; S100 calcium-binding protein A9 (calgranulin B); S100 calcium binding protein A9 (calgranulin B); p14
• Gene ID: 6280
• mRNA Refseq: NM_002965
• Protein Refseq: NP_002956
• MIM: 123886
• UniProt ID: P06702
• Chromosome Location: 1q21
• Function: calcium ion binding; protein binding; signal transducer activity

Reviews

08/17/2021

This includes complementary reagents, protocols, and access to an extensive knowledge base, all aimed at streamlining the trial process and maximizing the chances of achieving meaningful results.

06/20/2016

By choosing the S100A9 protein and partnering with the manufacturer, researchers can confidently conduct their trials, achieve reliable results, and contribute to groundbreaking discoveries.

04/04/2016

Collaborating with the manufacturer opens up possibilities for potential collaboration and exchange of information with a wider scientific community, allowing researchers to stay at the forefront of advancements in their respective fields.

Q&As

How is S100A9 protein measured in clinical settings?

S100A9 levels can be measured using various laboratory techniques, such as ELISA (enzyme-linked immunosorbent assay).

Are there any therapies or drugs targeting S100A9 in clinical development?

Some research is exploring the development of drugs that target S100A9 to modulate inflammation, but clinical applications are still in the experimental phase.

Can S100A9 levels be used as a biomarker for specific diseases?

Yes, elevated S100A9 levels have been associated with conditions like rheumatoid arthritis and inflammatory bowel disease, making it a potential biomarker.

Can S100A9 be used to predict disease outcomes?

Elevated S100A9 levels have been linked to poorer outcomes in certain diseases, making it a potential predictor of disease severity.

Are there any genetic factors that influence S100A9 levels?

Genetic variations can influence S100A9 expression, and these variations may impact an individual's susceptibility to certain diseases.