Active Recombinant Human Calprotectin S100A9 Protein

• Cat.No.: S100A9-1019H
• Product Overview: Recombinant Human S100 calcium binding protein A9 antigen is produced by E.coli expression system and the target gene encoding Thr2-Pro114 is expressed. Predicted molecular weight: 13 kDa.

Specification

• Antigen Description: Calprotectin belongs to the family of S100 proteins and is composed of two subunits S100A8 and S100A9. Increased plasma concentrations are found in response to infections and inflammation. Faecal calprotectin measurement is used for detection of gastrointestinal inflammation or neoplasia and for assessment of inflammatory bowel disease activity and response to treatment.
• Description: Calprotectin belongs to the family of S100 proteins and is composed of two subunits S100A8 and S100A9. Increased plasma concentrations are found in response to infections and inflammation. Faecal calprotectin measurement is used for detection of gastrointestinal inflammation or neoplasia and for assessment of inflammatory bowel disease activity and response to treatment.
• Source: E. coli
• Species: Human
• Form: Lyophilized
• Bio-activity: Anti-h Calprotectin 3403: + Anti-h Calprotectin 3404: - Anti-h Calprotectin 3405: - Anti-h Calprotectin 3406: - Anti-h Calprotectin 3407: -
• Molecular Mass: 13kDa
• AA Sequence: TCKMSQLERNIETIINTFHQYSVKL GHPDTLNQGEFKELVRKDLQNFLKK ENKNEKVIEHIMEDL DTNADKQLSFEEFIMLMARLTWASH EKMHEGDEGPGHHHKPGLGEGTP
• Purity: >90% by SDS-PAGE
• Storage: -20centigrade
• Concentration: 0.5 mg/ml when reconstituted with 1000 µl of deionized water
• Storage Buffer: PBS, pH 7.4
• Reconstitution: Reconstitute lyophilized protein with 1000 µl of deionized water
• Tag: Non
• Protein length: Thr2-Pro114

Gene Information

• Gene Name: S100A9 S100 calcium binding protein A9 [ Homo sapiens ]
• Official Symbol: S100A9
• Synonyms: S100A9; S100 calcium binding protein A9; CAGB, CFAG, S100 calcium binding protein A9 (calgranulin B) , S100 calcium binding protein A9 (calgranulin B); protein S100-A9; 60B8AG; CGLB; LIAG; MAC387; MIF; MRP14; NIF; P14; MRP-14; calgranulin B; calgranulin-B; calprotectin L1H subunit; leukocyte L1 complex heavy chain; migration inhibitory factor-related protein 14; S100 calcium-binding protein A9 (calgranulin B); CAGB; CFAG; L1AG
• Gene ID: 6280
• mRNA Refseq: NM_002965
• Protein Refseq: NP_002956
• MIM: 123886
• UniProt ID: P06702

Reviews

08/17/2021

This includes complementary reagents, protocols, and access to an extensive knowledge base, all aimed at streamlining the trial process and maximizing the chances of achieving meaningful results.

06/20/2016

By choosing the S100A9 protein and partnering with the manufacturer, researchers can confidently conduct their trials, achieve reliable results, and contribute to groundbreaking discoveries.

04/04/2016

Collaborating with the manufacturer opens up possibilities for potential collaboration and exchange of information with a wider scientific community, allowing researchers to stay at the forefront of advancements in their respective fields.

Q&As

How is S100A9 protein measured in clinical settings?

S100A9 levels can be measured using various laboratory techniques, such as ELISA (enzyme-linked immunosorbent assay).

Are there any therapies or drugs targeting S100A9 in clinical development?

Some research is exploring the development of drugs that target S100A9 to modulate inflammation, but clinical applications are still in the experimental phase.

Can S100A9 levels be used as a biomarker for specific diseases?

Yes, elevated S100A9 levels have been associated with conditions like rheumatoid arthritis and inflammatory bowel disease, making it a potential biomarker.

Can S100A9 be used to predict disease outcomes?

Elevated S100A9 levels have been linked to poorer outcomes in certain diseases, making it a potential predictor of disease severity.

Are there any genetic factors that influence S100A9 levels?

Genetic variations can influence S100A9 expression, and these variations may impact an individual's susceptibility to certain diseases.