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Official Full Name sialic acid binding Ig-like lectin 5
Background This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface;lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition;sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits;the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B;Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.
Synonyms SIGLEC5; sialic acid binding Ig-like lectin 5; CD33L2; sialic acid-binding Ig-like lectin 5; CD170; OB BP2; SIGLEC 5; CD33 antigen-like 2; OB-binding protein 2; obesity-binding protein 2; sialic acid-binding immunoglobulin-like lectin 5; OBBP2; OB-BP2; SI
    • Species :
    • Human
    • Rhesus monkey
    • Source :
    • E. coli
    • E.coli
    • HEK293
    • HEK293T
    • Human Cell
    • NS0
    • Tag :
    • Fc
    • His
    • S
    • His-Avi
    • human
    • IgG1
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human SIGLEC5-098H Recombinant Human SIGLEC5 protein, His-Avi-tagged HEK293 His-Avi
    Human SIGLEC5-1075HCL Recombinant Human SIGLEC5 cell lysate Human Cell N/A
    Human SIGLEC5-1505HCL Recombinant Human SIGLEC5 cell lysate Human Cell N/A
    Human SIGLEC5-428H Recombinant Human SIGLEC5 Protein HEK293 N/A
    Human SIGLEC5-514H Recombinant Human SIGLEC5 protein, His-tagged E. coli His
    Human SIGLEC5-5674H Recombinant Human SIGLEC5 protein, His & S-tagged E.coli His/S
    Human SIGLEC5-5941H Recombinant Human SIGLEC5 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human SIGLEC5-7330H Recombinant Human SIGLEC5 protein, Fc-tagged HEK293 human/IgG1/Fc
    Human SIGLEC5-941H Recombinant Human SIGLEC5 Protein, Fc Chimera NS0 Fc
    Rhesus monkey SIGLEC5-1596R Recombinant Rhesus Monkey SIGLEC5 Protein HEK293 N/A

    siglec5 involved in several pathways and played different roles in them. We selected most pathways siglec5 participated on our site, such as Adaptive Immune System, Immune System, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with siglec5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System STIM1B; HUWE1; RAP1GAP2B; DCTN1; BTLA; ASB9; RASGRP2; FBXO44; UBE2U; LRSAM1
    Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell CD200R1; KLRF1; LILRA2; LILRA3; SIGLEC11; CLEC2B; SIGLEC8; CLEC2G; GM11711; LAIR2

    siglec5 has several biochemical functions, for example, carbohydrate binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by siglec5 itself. We selected most functions siglec5 had, and list some proteins which have the same functions with siglec5. You can find most of the proteins on our site.

    Function Related Protein
    carbohydrate binding GALNT4; LMAN1L; GALNT12; ASGR1; KLRB1F; LGALS2B; CLEC18B; SIGLEC9; CLEC2H; Siglec1
    protein binding TRPC4; STX3; TMEM59; NRIP2; SPATC1; HESX1; PGLS; GABARAP; POU2AF1; Raet1a

    siglec5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with siglec5 here. Most of them are supplied by our site. Hope this information will be useful for your research of siglec5.

    TRIP13; VAC14; q7cjv9_yerpe

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