• Official Full Name

    SPARC-like 1 (hevin)

  • Synonyms

    SPARCL1; SPARC-like 1 (hevin); SPARC like 1 (mast9, hevin); SPARC-like protein 1; MAST9; Ecm2; RAGS1 antigen; Extracellular matrix protein 2; Hevin; High endothelial venule protein; MAST 9; Matrix glycoprotein Sc1; PIG33; proliferation inducing protein 33; SC1; SPARC like 1; SPRL1_HUMAN; SPARC-like 1 (mast9, hevin); proliferation-inducing protein 33;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Cell & Tissue Lysates
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • Mammalian Cell
  • Mammalian cells
  • His
  • His (Fc)
  • Avi
  • GST
  • His|GST
  • SUMO
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SPARCL1-89H Active Recombinant Human SPARCL1, His-tagged Mammalian cells His
Human SPARCL1-871H Recombinant Human SPARCL1, His tagged Human Cell His
Human SPARCL1-156H Recombinant Human SPARCL1 protein, His/GST-tagged E.coli His/GST
Human SPARCL1-2466H Recombinant Human SPARCL1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human SPARCL1-2418H Recombinant Human SPARCL1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human SPARCL1-4113H Recombinant Human SPARCL1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human SPARCL1-6625H Recombinant Human SPARCL1 Protein (Gly298-His545), N-GST tagged E.coli N-GST Gly298-His545
Human SPARCL1-4113H-B Recombinant Human SPARCL1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Sparcl1-877M Active Recombinant Mouse Sparcl1 protein, His-tagged HEK293 His Tyr368-Phe650
Mouse Sparcl1-536M Active Recombinant Mouse Sparcl1 protein, His-tagged HEK293 His Met1-Phe650
Mouse SPARCL1-745MCL Recombinant Mouse SPARCL1 cell lysate Human Cell N/A
Mouse Sparcl1-6074M Recombinant Mouse Sparcl1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat SPARCL1-5684R Recombinant Rat SPARCL1 Protein Mammalian Cell His
Rat SPARCL1-5343R Recombinant Rat SPARCL1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat SPARCL1-3315R Recombinant Rat SPARCL1 protein, His-GST-tagged E.coli His/GST Ser402~Asp627
Rat SPARCL1-5343R-B Recombinant Rat SPARCL1 Protein Pre-coupled Magnetic Beads HEK293
Rat SPARCL1-3320R Recombinant Rat SPARCL1 protein, His-SUMO-tagged E.coli His-SUMO Ser402~Asp627
Zebrafish SPARCL1-7088Z Recombinant Zebrafish SPARCL1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SPARCL1 Related Articles
  • SPARCL1 Related Research Area

SPARCL1 involved in several pathways and played different roles in them. We selected most pathways SPARCL1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SPARCL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

SPARCL1 has several biochemical functions, for example, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SPARCL1 itself. We selected most functions SPARCL1 had, and list some proteins which have the same functions with SPARCL1. You can find most of the proteins on our site.

Function Related Protein
calcium ion bindingMYL2;PLCD1A;FREM2;ACTN3A;CALB2B;CETN1;SWAP70;DLK2;PCDH2G12

SPARCL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SPARCL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SPARCL1.


Weaver, MS; Workman, G; et al. Processing of the Matricellular Protein Hevin in Mouse Brain Is Dependent on ADAMTS4. JOURNAL OF BIOLOGICAL CHEMISTRY 285:5868-5877(2010).
Brekken, RA; Sullivan, MM; et al. Expression and characterization of murine hevin (SC1), a member of the SPARC family of matricellular proteins. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 52:735-748(2004).
  • Q&As
  • Reviews

Q&As (5)

Ask a question
How does SPARCL1 influence cell adhesion and migration? 04/20/2023

SPARCL1 interacts with cell adhesion molecules and the extracellular matrix, influencing cell adhesion and migration in various physiological processes.

How is SPARCL1 linked to wound healing? 08/16/2021

SPARCL1 is involved in tissue repair and wound healing processes, influencing cell migration, adhesion, and extracellular matrix remodeling.

Can SPARCL1 be used as a predictive marker for patient outcomes in cancer? 07/26/2020

Studies suggest that low SPARCL1 expression is associated with poor prognosis in certain cancers, indicating its potential as a predictive marker.

Are there therapeutic implications for modulating SPARCL1 expression? 12/21/2019

Modulating SPARCL1 expression could be a potential therapeutic strategy, particularly in cancer treatment, by targeting tumor progression or metastasis.

In which types of cancer is SPARCL1 often downregulated? 06/20/2016

SPARCL1 is frequently downregulated in breast, lung, and colorectal cancers, suggesting a potential role as a prognostic marker.

Customer Reviews (3)

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    The bands of proteins in Western Blotting experiments were very clear.


      Researchers can rely on the SPARCL1 protein to deliver precise results, enhancing the credibility and efficiency of their experiments.


        The SPARCL1 protein is highly recommended for its exceptional performance in ELISA assays.

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