STAT5A

  • Official Full Name

    STAT5A signal transducer and activator of transcription 5A

  • Synonyms

    STAT5A; signal transducer and activator of transcription 5A; STAT5; MGF;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Human cells
  • Mammalian Cell
  • Mammalian cells
  • Sf9 Insect Cell
  • DYKDDDDK
  • Flag
  • His
  • His (Fc)
  • Avi
  • His|MBP
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human STAT5A-340H Recombinant Human STAT5A protein, His/MBP-tagged E.coli His/MBP
Human STAT5A-1498H Recombinant Human STAT5A, His-tagged Sf9 Insect Cell His
Human STAT5A-341H Recombinant Human STAT5A protein, His/MBP-tagged E.coli His/MBP
Human STAT5A-342H Recombinant Human STAT5A protein, His/MBP-tagged E.coli His/MBP
Human STAT5A-01H Recombinant Human STAT5a, His-tagged E.coli His
Human STAT5A-1416HCL Recombinant Human STAT5A 293 Cell Lysate HEK293 N/A
Human STAT5A-352HFL Recombinant Full Length Human STAT5A Protein, C-Flag-tagged Mammalian cells Flag
Human STAT5A-151H Recombinant Human STAT5A Protein, DYKDDDDK-tagged Human cells DYKDDDDK
Human STAT5A-0729H Recombinant Human STAT5A protein, His-tagged E.coli His
Human STAT5A-2117H Recombinant Human STAT5A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human STAT5A-4962H Recombinant Human STAT5A Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human STAT5A-6364H Recombinant Human STAT5A Protein (Met1-Ser794), N-His tagged E.coli N-His
Human STAT5A-2117H-B Recombinant Human STAT5A Protein Pre-coupled Magnetic Beads HEK293
Mouse Stat5a-6172M Recombinant Mouse Stat5a Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat STAT5A-5779R Recombinant Rat STAT5A Protein Mammalian Cell His
Rat STAT5A-5438R Recombinant Rat STAT5A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat STAT5A-5438R-B Recombinant Rat STAT5A Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque STAT5A-4518R Recombinant Rhesus monkey STAT5A Protein, His-tagged Mammalian Cell His
Rhesus Macaque STAT5A-4334R-B Recombinant Rhesus Macaque STAT5A Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque STAT5A-4334R Recombinant Rhesus Macaque STAT5A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish STAT5A-9737Z Recombinant Zebrafish STAT5A Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • STAT5A Related Gene Family
  • STAT5A Related Signal Pathway

STAT5A involved in several pathways and played different roles in them. We selected most pathways STAT5A participated on our site, such as ErbB signaling pathway, Jak-STAT signaling pathway, Prolactin signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with STAT5A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
ErbB signaling pathwayNCK1;MAPK3;MAPK9;MAPK10;SRC;CDKN1BA;HRAS;MAPK8A;GAB1
Jak-STAT signaling pathwayIl4ra;PRL2;IFNB1;CNTF;CRFB4;IL22;HRASB;IFNA6;IL21
Prolactin signaling pathwayCSH;MAPK3;GSK3B;FOS;ESR2;PIK3CA;KRAS;SIRPA;NFKB1
Hepatitis BPIK3CG;AKT1;ATF4;RELA;TRP53;CREB3L2;IFNA13;MAPK8;DDX58
MeaslesIfna15;AKT2;STAT1;EIF3H;CD28;EIF2AK3;IFNA6;AKT1;CCND3
HTLV-I infectionH2-AA;TNFRSF13C;CRTC3;Il2;WNT16;POLE3;ANAPC11;CD40;TNF
Pathways in cancerBRCA2;GNB2;IGF1;RUNX1T1;EPAS1;PLCB1;VEGFA;FADD;MECOM
Viral carcinogenesisATP6V0D1;STAT3;HNRNPK;HDAC2;HIST1H4A;GTF2H1;PKM2;HDAC11;UBE3A
Chronic myeloid leukemiaCRKL;CDK6;RUNX1;STAT5B;MAP2K1;HDAC2;NRAS;IKBKB;SOS1
Acute myeloid leukemiaMYC;SPI1;MTOR;RARA;PIK3CA;ARAF;STAT5B;BAD;NRAS

STAT5A has several biochemical functions, for example, RNA polymerase II core promoter sequence-specific DNA binding, protein binding, signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by STAT5A itself. We selected most functions STAT5A had, and list some proteins which have the same functions with STAT5A. You can find most of the proteins on our site.

Function Related Protein
RNA polymerase II core promoter sequence-specific DNA bindingH3F3A;RUVBL2;GATA1;SOX11;HOXB3;ZFP335;NR4A2;HNF4A;STAT5A
protein bindingMAPKAPK5;KIF7;SRM;FBP1;PNPT1;MSN;CDCA5;CHD2;IGFBP7
signal transducer activityCXCR4A;GNGT2;TACR1B;TMTOPS2B;GNAO1;V2RH14;STAT5B;STAT2;OPN4A
transcription factor activity, sequence-specific DNA bindingZFP518A;NFATC2;HOXA6;HOXB7;ZNF23;ZFP110;RCOR2;SOX11;YY1

STAT5A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STAT5A here. Most of them are supplied by our site. Hope this information will be useful for your research of STAT5A.

PTPN1; TCF12; AGAP2; STAP2; il2ra_human_gene

  • Q&As
  • Reviews

Q&As (5)

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How does STAT5A contribute to immune system regulation? 01/28/2022

STAT5A plays a crucial role in regulating immune responses by influencing the differentiation and function of immune cells such as T cells and natural killer cells.

Are there any ongoing clinical trials targeting STAT5A? 12/01/2020

Yes, several clinical trials are exploring the therapeutic potential of targeting STAT5A in different cancer types.

What challenges are associated with targeting STAT5A in clinical applications? 07/17/2019

One challenge is the need for specificity in targeting STAT5A to avoid adverse effects on normal cellular functions.

Can STAT5A be a prognostic marker in cancer patients? 01/05/2018

Elevated levels of activated STAT5A have been correlated with poor prognosis in certain cancers, suggesting its potential as a prognostic marker.

In which diseases are dysregulations of STAT5A associated? 12/25/2017

Dysregulations of STAT5A have been linked to leukemia, breast cancer, and prostate cancer, among other diseases.

Customer Reviews (3)

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Reviews
10/17/2022

    The manufacturer offers exceptional technical assistance, guiding researchers through various stages of their experiments.

    10/04/2016

      Its reliable bioactivity makes it an ideal choice for a diverse range of experimental applications.

      05/29/2016

        By providing comprehensive data and resources, the manufacturer enables researchers to design and implement their trials with confidence, ensuring the desired outcomes.

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