Recombinant Human STAT5A, His-tagged
Cat.No. : | STAT5A-1498H |
Product Overview : | Recombinant full-length human STAT5 was expressed by baculovirus inSf9insect cells using an N-terminal His tag. MW = 92 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | STAT5A-1498H |
Description : | STAT5 (signal transducers and activators of transcription 5) is a member of the STAT family and this protein is phosphorylated by receptor associated protein kinases in response to cytokines and growth factors. The differentiation of T helper (Th) cells is regulated by members of the STAT family of signaling molecules. In BCR-ABL-positive cells, STAT5 is constitutively activated by tyrosine phosphorylation. STAT5 activation results in upregulation of Bcl-XL and increased resistance to induction of apoptosis. STAT5 is involved in expression and growth hormone-mediated sexually dimorphic regulation of cytochrome P450 3A10/lithocholic acid 6 beta-hydroxylase. |
Source : | Sf9 insect cells using baculovirus. |
Sequence : | Full-length. |
Applications : | Kinase Assay, Western Blot. |
Storage And Stability : | Store product at -70℃. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | STAT5A signal transducer and activator of transcription 5A [ Homo sapiens ] |
Synonyms : | STAT5A; signal transducer and activator of transcription 5A; MGF; STAT5; STAT5 |
Gene ID : | 6776 |
mRNA Refseq : | NM_003152 |
Protein Refseq : | NP_003143 |
MIM : | 601511 |
UniProt ID : | P42229 |
Chromosome Location : | 17q11.2 |
Pathway : | Acute myeloid leukemia; Chronic myeloid leukemia; ErbB signaling pathway; Jak-STAT signaling pathway; Pathways in cancer |
Function : | calcium ion binding; phosphate binding; protein binding; signal transducer activity; transcription factor activity |
Products Types
◆ Recombinant Protein | ||
STAT5A-5438R | Recombinant Rat STAT5A Protein, His (Fc)-Avi-tagged | +Inquiry |
STAT5A-2117H | Recombinant Human STAT5A Protein, His (Fc)-Avi-tagged | +Inquiry |
Stat5a-6172M | Recombinant Mouse Stat5a Protein, Myc/DDK-tagged | +Inquiry |
STAT5A-4334R | Recombinant Rhesus Macaque STAT5A Protein, His (Fc)-Avi-tagged | +Inquiry |
STAT5A-0729H | Recombinant Human STAT5A protein, His-tagged | +Inquiry |
◆ Lysates | ||
STAT5A-1416HCL | Recombinant Human STAT5A 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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