Recombinant Human STAT5A Protein, DYKDDDDK-tagged STAT5A-151H

Recombinant Human STAT5A Protein, DYKDDDDK-tagged

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Cat.No. : STAT5A-151H Optional Service: Optional requirements on this protein
Product Overview : Recombinant Human signal transducer and activator of transcription 5A(STAT5A) protein, transcript variant 2(NM_003152), with a DYKDDDDK tag, was expressed in human cells.
Description : The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been found for this gene.
Source : Human cells
Species : Human
Tag : DYKDDDDK
Form : Purified protein formulated in a sterile solution of TBS buffer, pH7.33, without any preservatives.
Molecular Mass : 90.5 kDa
Endotoxin : Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Purity : >90% by SDS-PAGE gel and Coomassie Blue staining
Applications : Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies.
Gene Name : STAT5A signal transducer and activator of transcription 5A [ Homo sapiens ]
Official Symbol : STAT5A
Synonyms : STAT5A; signal transducer and activator of transcription 5A; STAT5; MGF;
Gene ID : 6776
mRNA Refseq : NM_003152
Protein Refseq : NP_003143
MIM : 601511
UniProt ID : P42229
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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