STEAP1

  • Official Full Name

    six transmembrane epithelial antigen of the prostate 1

  • Overview

    This gene is predominantly expressed in prostate tissue, and is found to be upregulated in multiple cancer cell lines. The gene product is predicted to be a six-transmembrane protein, and was shown to be a cell surface antigen significantly expressed at cell-cell junctions.
  • Synonyms

    STEAP1; six transmembrane epithelial antigen of the prostate 1; six transmembrane epithelial antigen of the prostate , STEAP; metalloreductase STEAP1; PRSS24; six-transmembrane epithelial antigen of prostate 1; STEAP; MGC19484;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Sus scrofa (Pig)
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • In vitro E. coli expression system
  • Mammalian cells
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • SUMO
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human STEAP1-297H Active Recombinant Human STEAP1 Full Length Transmembrane protein(Nanodisc) HEK293 N/A
Human STEAP1-574H Active Recombinant Human STEAP1 protein, His-tagged(Detergent) HEK293 His Glu 2 - Leu 339
Human STEAP1-3000H Recombinant Human STEAP1 protein, His-tagged E.coli His 1-80 aa
Human STEAP1-1710HCL Recombinant Human STEAP1 cell lysate N/A
Human STEAP1-2120H-B Recombinant Human STEAP1 Protein Pre-coupled Magnetic Beads HEK293
Human STEAP1-399HFL Recombinant Full Length Human STEAP1 Protein, C-Flag-tagged Mammalian cells Flag
Human STEAP1-2899H Recombinant Human STEAP1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human STEAP1-5801H Recombinant Human STEAP1 Protein (Met1-His72), N-GST tagged E.coli N-GST Met1-His72
Human STEAP1-2472H Recombinant Human STEAP1 Full Length Transmembrane protein, His-SUMO-tagged In vitro E. coli expression system His-SUMO 1-339aa
Human STEAP1-3928H Recombinant Human STEAP1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human STEAP1-2120H Recombinant Human STEAP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human STEAP1-5281H Recombinant Human STEAP1 protein, GST-tagged E.coli GST 3-69aa
Mouse Steap1-6177M Recombinant Mouse Steap1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Homo sapiens (Human) RFL3571HF Recombinant Full Length Human Metalloreductase Steap1(Steap1) Protein, His-Tagged E.coli expression system His Full Length (1-339aa)
Mus musculus (Mouse) RFL24698MF Recombinant Full Length Mouse Metalloreductase Steap1(Steap1) Protein, His-Tagged E.coli expression system His Full Length (1-339)
Sus scrofa (Pig) RFL9628SF Recombinant Full Length Pig Metalloreductase Steap1(Steap1) Protein, His-Tagged E.coli expression system His Full Length (1-338)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

STEAP1 involved in several pathways and played different roles in them. We selected most pathways STEAP1 participated on our site, such as Mineral absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with STEAP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Mineral absorptionSLC34A2;ATOX1;TRPM6;ATP1A2;ATP1B2;SLC26A3;TRPV6;SLC9A3;SLC31A1

STEAP1 has several biochemical functions, for example, channel activity, NOT cupric reductase activity, NOT ferric-chelate reductase (NADPH) activity. Some of the functions are cooperated with other proteins, some of the functions could acted by STEAP1 itself. We selected most functions STEAP1 had, and list some proteins which have the same functions with STEAP1. You can find most of the proteins on our site.

Function Related Protein
channel activityP2RX6;BCL2;PANX1B;BAX;BAXB;STEAP1;GJA8;MAL;APNL
NOT cupric reductase activity
NOT ferric-chelate reductase (NADPH) activity
metal ion bindingDNLZ;RPS27.2;SOBPB;DEAF1;ENOPH1;KAT8;TRMT13;RAF1A;CHORDC1
transporter activityCHP;VPS9D1;SLC6A20B;SLC5A6B;LCN12;ABCC1;SLC15A3;SLC25A38;SLC12A5B

STEAP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STEAP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of STEAP1.

  • Q&As
  • Reviews

Q&As (5)

Ask a question
Can STEAP1 protein be used for cancer screening? 12/21/2022

Studies suggest that STEAP1 protein levels can be used as a biomarker for cancer screening and early detection.

What are the implications of STEAP1 protein in drug resistance? 07/01/2022

Understanding the role of STEAP1 in drug resistance may lead to the development of combination therapies to overcome resistance in cancer treatment.

How is STEAP1 protein being studied in clinical trials? 05/20/2018

Clinical trials are exploring the use of STEAP1-targeted therapies in various cancer types, including prostate, bladder, and breast cancer.

Are there any drugs targeting STEAP1 protein? 06/27/2017

Several studies are investigating the use of targeted therapies and immunotherapies that specifically target STEAP1 in cancer treatment.

How does STEAP1 protein affect tumor growth and metastasis? 12/03/2016

Studies have suggested that STEAP1 may play a role in promoting tumor growth and metastasis, making it an attractive target for cancer therapy.

Customer Reviews (3)

Write a review
Reviews
09/10/2020

    I am confident that the STEAP1 protein will unlock vital insights into cellular processes, propelling my scientific investigations to new heights.

    10/22/2016

      The STEAP1 protein stands as a remarkable solution that exemplifies exceptional quality and meets all my experimental requirements.

      04/18/2016

        Its impressive purity and functional characteristics make it an ideal choice for my research endeavors, ensuring reliable and impactful results.

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