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Official Full Name SUB1 SUB1 homolog (S. cerevisiae)
Background The human PC4 (also called p15) is a non-TAF transcription coactivator that mediates activator-dependent transcription by RNA polymerase II in vitro through most tested activators. The function of PC4 is apparently through interactions with transcriptional activators and the basal transcription machinery. It is negatively regulated by casein kinase II phosphorylation both in vivo and in vitro. PC4 strongly binds single stranded DNA and regulates HSSB (RPA)-dependent SV40 DNA replication. Recent studies indicated that PC4 can be acetylated by several histone acetyltransferase.
Synonyms SUB1; SUB1 homolog (S. cerevisiae); activated RNA polymerase II transcriptional coactivator p15; p14; p15; PC4; positive cofactor 4; activated RNA polymerase II transcription cofactor 4; P15; MGC102747;
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • E.Coli or Yeast
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human SUB1-1080H Recombinant Human SUB1 Homolog(S. cerevisiae) E.coli N/A
    Human SUB1-1368HCL Recombinant Human SUB1 293 Cell Lysate HEK293 N/A
    Human SUB1-2499H Recombinant Human SUB1 Homolog(S. cerevisiae), His-tagged E.coli His
    Human SUB1-3040H Recombinant Human SUB1, GST-tagged E.coli GST
    Human SUB1-30794TH Recombinant Human SUB1, His-tagged E.coli His
    Human SUB1-31457TH Recombinant Human SUB1 E.coli N/A
    Human SUB1-562H Recombinant Human SUB1, His tagged E.coli His
    Mouse SUB1-16206M Recombinant Mouse SUB1 Protein Mammalian Cell His
    Mouse Sub1-3110M Recombinant Mouse Sub1, His-tagged E.Coli or Yeast His
    Rat SUB1-5822R Recombinant Rat SUB1 Protein Mammalian Cell His
    Cynomolgus Monkey SUB1-987C Recombinant Cynomolgus SUB1 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque SUB1-4554R Recombinant Rhesus monkey SUB1 Protein, His-tagged Mammalian Cell His
    Chicken SUB1-1857C Recombinant Chicken SUB1 Mammalian Cell His

    sub1 involved in several pathways and played different roles in them. We selected most pathways sub1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with sub1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    sub1 has several biochemical functions, for example, poly(A) RNA binding, protein binding, single-stranded DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by sub1 itself. We selected most functions sub1 had, and list some proteins which have the same functions with sub1. You can find most of the proteins on our site.

    Function Related Protein
    poly(A) RNA binding SAP18; MAZ; RPL13A; RPL28; RPL5B; KIAA1429; EWSR1; PCBP1; NUDT21; SRSF9
    protein binding CD244; FAM3C; PPP1R9A; MEOX2; NFYB; NLRX1; LTC4S; PDE4D; OLIG3; MED15
    single-stranded DNA binding RAD23B; ALYREF; RAD51C; SETMAR; SWSAP1; CDC45; MCM4; CDAN1; SUB1; PCBP1
    transcription coactivator activity HIF3A; NACA; FHL5; ELF3; SAP130; ASXL1; ZEB1; RNF20; CALCOCO1; TADA3
    transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding HOXB5; PROP1; SIX3; REL; NFE2L1; SIX6; CUX1; HCFC1; POU4F1; CDX1

    sub1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with sub1 here. Most of them are supplied by our site. Hope this information will be useful for your research of sub1.

    CSNK2A1; tat_hv112; Rep68; CSTF2; Rep40; Kif1c; Shoc2; CSTF2; Rep78; PINX1; midostaurin

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