TAF13

  • Official Full Name

    TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa

  • Overview

    Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit associated with a subset of TFIID complexes. This subunit interacts with TBP and with two other small subunits of TFIID, TAF10 and TAF11. There is a pseudogene located on chromosome 6.

  • Synonyms

    TAF13;TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa;TAF2K, TATA box binding protein (TBP) associated factor, RNA polymerase II, K, 18kD;transcription initiation factor TFIID subunit 13;TAFII18;MGC22425;TAF(II)18;TAF13 RNA polymerase II, TATA box binding protein (TBP) associated factor, 18kDa;TAF13_HUMAN;TAF2K;TAFII 18;TAFII-18;Transcription initiation factor TFIID 18 kDa subunit;OTTHUMP00000039343;OTTHUMP00000039344;transcription initiation factor TFIID 18 kD subunit;TATA box binding protein (TBP)-associated factor, RNA polymeras

Recombinant Proteins

  • Human
  • Zebrafish
  • Chicken
  • Mouse
  • E.coli
  • Mammalian Cells
  • HEK293
  • GST
  • His
  • T7
  • Non
  • DDK
  • Myc
Cat.# Product name Source (Host) Species Tag Protein Length Price
TAF13-821H Recombinant Human TAF13 Protein, GST-tagged E.coli Human GST 1-124 aa
TAF13-1226H Recombinant Human TAF13 protein, His & T7-tagged E.coli Human His&T7 Met1~Ser124
TAF13-1375Z Recombinant Zebrafish TAF13 Mammalian Cells Zebrafish His
TAF13-1399C Recombinant Chicken TAF13 Mammalian Cells Chicken His
TAF13-1275HCL Recombinant Human TAF13 293 Cell Lysate HEK293 Human Non
Taf13-6277M Recombinant Mouse Taf13 Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
TAF13-6393H Recombinant Human TAF13 Protein (Met1-Ser124), N-His tagged E.coli Human His Met1-Ser124
TAF13-826H Recombinant Human TAF13 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc

    Involved Pathway

    TAF13 involved in several pathways and played different roles in them. We selected most pathways TAF13 participated on our site, such as Basal transcription factors,Herpes simplex infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAF13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Basal transcription factors TAF15,GTF2B,TBPL1,TAF10,TAF4B,GTF2H2C,ERCC3,GTF2H3-2,GTF2I,TAF12
    Herpes simplex infection MHC2DEB,TRAF2,BMA2,GLTSCR2,C3A.2,CLOCK,HLA-C,IFNA12,TYK2,PML

    Protein Function

    TAF13 has several biochemical functions, for example, DNA binding,protein C-terminus binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TAF13 itself. We selected most functions TAF13 had, and list some proteins which have the same functions with TAF13. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding POLR2I,TBPL1,POLR3C,ZFP13,SMAD9,RXRAA,SOX21A,ZFP36L1,MCM2,ZIC2
    protein C-terminus binding CTGF,CLIC6,MKI67,CD2AP,OPRL1,HOMER3,PDZD3,PROP1,BLOC1S2,HSPB7
    transcription cofactor activity SND1,LDB1A,RFXANK,CREB1,ZNF212,NFKBIZ,KAT2B,THRAP3,ANKRA2,ELK4
    protein heterodimerization activity RAB3GAP2,PVRL1,VEGFA,MAFG,TCF4,ATF1,DDIT3,ADRA1B,BAXB,NAE1
    transcription factor activity, sequence-specific DNA binding CTBP1,POU4F3,NFKB2,HIC1,HOXB8B,YBX1,ZNF323,STAT5B,NKX6-2,KDM3A
    protein binding BOC,TRIM32,KAT8,GYPB,SLC4A4,RBM15B,AKAP13,CRIPAK,VARS,HBD

    Interacting Protein

    TAF13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAF13 here. Most of them are supplied by our site. Hope this information will be useful for your research of TAF13.

    MTUS2;TAF11;h3_peptide_2-18;MED26;CERK;NAF1;NLRP2

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