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TDO2

  • Official Full Name

    tryptophan 2,3-dioxygenase

  • Overview

    Tryptophan 2,3-dioxygenase (EC 1.13.11.11) plays a role in catalyzing the first and rat-limiting step in the kynurenine pathway, the major pathway of tryptophan metabolism.
  • Synonyms

    TDO2; tryptophan 2,3-dioxygenase; TDO; TPH2; 3-dioxygenase; T23O_HUMAN; TDO 2; TO; TRPO; Tryptamin 2 3 dioxygenase; Tryptamin 2; Tryptophan 2 3 dioxygenase; Tryptophan 2; Tryptophan oxygenase; Tryptophan pyrrolase; Tryptophanase; tryptamin 2,3-dioxygenase;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • Mamanlian cells
  • Mammalian Cell
  • Sf9 Insect Cell
  • Yeast
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|SUMO
  • SUMO
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • T7
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TDO2-824H Active Recombinant Human TDO2, MYC/DDK-tagged HEK293 Myc/DDK
Human TDO2-823H Recombinant Human Tryptophan 2,3-Dioxygenase, T7-tagged E.coli T7
Human TDO2-825H Recombinant Human TDO2, GST-tagged Sf9 Insect Cell GST Full Length
Human TDO2-3171H Recombinant Human TDO2, GST-tagged E.coli GST 55-406aa
Human TDO2-724H Recombinant Human TDO2 protein, His-tagged E.coli His
Human TDO2-31212TH Recombinant Human TDO2 E.coli N/A
Human TDO2-2503H Recombinant Human Tryptophan 2,3-Dioxygenase, His-tagged E.coli His 1-406aa
Human TDO2-385H Recombinant Human TDO2 Mammalian Cell His
Human TDO2-1156HCL Recombinant Human TDO2 293 Cell Lysate HEK293 N/A
Human TDO2-4170H Recombinant Human TDO2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human TDO2-3557H Recombinant Human TDO2 protein, His-SUMO-tagged E.coli His-SUMO 1-406aa
Human TDO2-1535H Recombinant Human TDO2 Protein (1-406 aa), His-tagged Yeast His 1-406 aa
Human TDO2-6516H Recombinant Human TDO2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human TDO2-7413HFL Recombinant Full Length Human TDO2, Flag-tagged Mamanlian cells Flag
Human TDO2-3408H Recombinant Human TDO2 protein, His-tagged E.coli His 55-406 aa
Human TDO216711H Recombinant Human TDO2 (1-406) Protein
Human TDO2-3558H Recombinant Human TDO2 protein, His-SUMO-tagged E.coli His-SUMO 1-406aa
Human TDO25033H Recombinant Human TDO2 (39-389) Protein
Human TDO2-4170H-B Recombinant Human TDO2 Protein Pre-coupled Magnetic Beads HEK293
Mouse TDO2-16601M Recombinant Mouse TDO2 Protein Mammalian Cell His
Mouse Tdo2-3559M Recombinant Mouse Tdo2 protein, His-tagged E.coli His 1-406aa
Mouse TDO2-1536M Recombinant Mouse TDO2 Protein (1-406 aa), His-tagged Yeast His 1-406 aa
Mouse TDO2-9103M Recombinant Mouse TDO2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse TDO2-9103M-B Recombinant Mouse TDO2 Protein Pre-coupled Magnetic Beads HEK293
Mouse Tdo2-6347M Recombinant Mouse Tdo2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat TDO2-5997R Recombinant Rat TDO2 Protein Mammalian Cell His
Rat TDO2-5656R-B Recombinant Rat TDO2 Protein Pre-coupled Magnetic Beads HEK293
Rat TDO2-5656R Recombinant Rat TDO2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat TDO2-1958R Recombinant Rat TDO2 Protein (1-406 aa), His-SUMO-tagged E.coli His/SUMO 1-406 aa
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • TDO2 Related Research Area

TDO2 involved in several pathways and played different roles in them. We selected most pathways TDO2 participated on our site, such as Tryptophan metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with TDO2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Tryptophan metabolismTDO2A;ALDH2.1;ALDH2.2;TDO2B;AOC1;TDO2;OGDHA;ALDH9A1B;CAT
Metabolic pathwaysPCYT1A;ALDH2.2;SGMS2;GCLM;SDSL;PYCRL;IMPDH2;CERS2A;HDC

TDO2 has several biochemical functions, for example, amino acid binding, heme binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TDO2 itself. We selected most functions TDO2 had, and list some proteins which have the same functions with TDO2. You can find most of the proteins on our site.

Function Related Protein
amino acid bindingTPH2;AGXT;GOT2;AARS2;KARS;AARS;TAT;TPH1B;TPH1
heme bindingBACH1;DGCR8;CYP11C1;CYP4V7;HBAE1;CYP2Y3;HBAD;CYP2A7;CYP2C19
metal ion bindingAMHR2;KLF12B;IDO1;HIVEP2A;DZIP1L;CTCFL;BA1;ZNF334;MIPEP
oxygen bindingCYP2D6;CYP2K16;CYP2P6;CYP2C50;CYP2C37;HBB-B2;CYP1A4;CYP2K17;CYP2AD2
protein bindingTOR1AIP1;INIP;PI4KA;FSHR;GRK6;ZCCHC13;TOMM7;GAN;CAMK1
tryptophan 2,3-dioxygenase activityIDO2;TDO2;TDO2A;IDO1;TDO2B

TDO2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TDO2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TDO2.

ASMTL; SDCBP; DPM1; EIF4E; MOB3C; ZFYVE26

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