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TRAF1

  • Official Full Name

    TNF receptor-associated factor 1

  • Overview

    TRAFs (TNF receptor-associated factors) are a family of multifunctional adaptor proteins that bind to surface receptors and recruit additional proteins to form multiprotein signaling complexes capable of promoting cellular responses (1-3). Members of the
  • Synonyms

    TRAF1; TNF receptor-associated factor 1; EBI6; Epstein-Bar virus-induced protein 6; MGC:10353;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • His|GST
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TRAF1-29978TH Recombinant Human TRAF1, His-tagged E.coli His 151 amino acids
Human TRAF1-31600TH Recombinant Human TRAF1, His-tagged E.coli His 151 amino acids
Human TRAF1-2478H Recombinant Human TNF Receptor-associated Factor 1, His-tagged E.coli His
Human TRAF1-825HCL Recombinant Human TRAF1 293 Cell Lysate HEK293 N/A
Human TRAF1-2806H Recombinant Human TRAF1 protein, His-tagged E.coli His 1-416 aa
Human TRAF1-2848H Recombinant Human TRAF1 protein, His-tagged E.coli His 173-295 aa
Human TRAF1-389H Recombinant Human TRAF1 Protein, His/GST-tagged E.coli His/GST Gly131~Ala381
Human TRAF1-966H Recombinant Human TRAF1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse TRAF1-17283M Recombinant Mouse TRAF1 Protein Mammalian Cell His
Mouse Traf1-6616M Recombinant Mouse Traf1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Traf1-390M Recombinant Mouse Traf1 Protein, His-tagged E.coli His Leu169~Ala392
Mouse TRAF1-9555M-B Recombinant Mouse TRAF1 Protein Pre-coupled Magnetic Beads HEK293
Mouse TRAF1-9555M Recombinant Mouse TRAF1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque TRAF1-4930R Recombinant Rhesus monkey TRAF1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque TRAF1-4744R-B Recombinant Rhesus Macaque TRAF1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque TRAF1-4744R Recombinant Rhesus Macaque TRAF1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish TRAF1-6882Z Recombinant Zebrafish TRAF1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

TRAF1 involved in several pathways and played different roles in them. We selected most pathways TRAF1 participated on our site, such as NF-kappa B signaling pathway, TNF signaling pathway, Herpes simplex infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRAF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
NF-kappa B signaling pathwayLY96;ICAM1;MAP3K7IP3;CCL4L1;IL1B;TNFSF14;RELB;CCL4;TNFAIP3
TNF signaling pathwayRELA;MAP2K7;TRAF5;RPS6KA5;PIK3CA;FOS;MAP3K7;CCL20;CCL5
Herpes simplex infectionMHC1UXA2;SRPK1;IFNGR1;TBPL2;BMA1;HNRNPK;TAF3;C5;TAF6L
Epstein-Barr virus infectionSFPI1;PIK3R5;CR2;PIK3R1;MAP3K14;Fcer2a;CD40;MAP2K6;EIF2AK1
Pathways in cancerCBLB;RXRG;CXCR4;BID;CYCS;FN1;Fzd4;PRKCB;CBL
Transcriptional misregulation in cancerNFKBIZ;HOXA9;WNT16;WHSC1;Bcl2a1b;NUPR1;IGF1;TAF15;ZEB1
Viral carcinogenesisHIST1H2BA;HIST1H2BC;CREB5;HIST1H2BD;HIST2H4A;HIST1H4L;CREB3L2;MAPKAPK2;ATF4
Small cell lung cancerLAMB1;BIRC2;BIRC8;ITGA2;CASP9;NOS2;ITGA2B;RB1;ITGAV

TRAF1 has several biochemical functions, for example, protein binding, thioesterase binding, tumor necrosis factor receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRAF1 itself. We selected most functions TRAF1 had, and list some proteins which have the same functions with TRAF1. You can find most of the proteins on our site.

Function Related Protein
protein bindingKIAA0319L;ALAS2;PNMA5;ANO2;USP54;E2F2;MCM8;ZCCHC8;ERLIN1
thioesterase bindingCALM1;TRAF4;CALM;CDC42;ARF6;HAUS7;TRAF6;RAC1;TRAF1
tumor necrosis factor receptor bindingTNFB;TNF;LTB;TRAF2;TNFSF10;CD40LG;TNFSF12;TRADD;Fasl
ubiquitin protein ligase bindingMUL1;UBE2W;CASP8;MAGEA2;DERL1;UBE2J2;UBXN6;TUBA1B;UBE2G2
zinc ion bindingBARD1;KDM5B;MMP19;ADH1A;MSL2;LMO7B;ADAMTS18;PGLYRP6;ZNF385C

TRAF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRAF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRAF1.

TRAF6; RIPK1; TRAF2

Research Area

Related articles

Lassen, UN; Meulendijks, D; et al. APhase I Monotherapy Study of RG7212, a First-in-Class Monoclonal Antibody Targeting TWEAK Signaling in Patients with Advanced Cancers. CLINICAL CANCER RESEARCH 21:258-266(2015).
Settin, A; Salama, A; et al. Signal transducer and activator of transcription 4 (STAT4) G > T gene polymorphism in Egyptian cases with rheumatoid arthritis. HUMAN IMMUNOLOGY 75:863-866(2014).
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