Recombinant Human TNF Receptor-associated Factor 1, His-tagged

• Cat.No.: TRAF1-2478H
• Product Overview: Recombinant human TRAF1 protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. MW = 19.5 kDa (172aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: TRAF1, also known as TNF receptor-associated factor 1, belongs to TNF receptor superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The complex also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 0.1M NaCl,1mM DTT.
• Purity: > 95% by SDS – PAGE.
• Concentration: 0.5 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MDGTFLWKIT NVTRRCHESA CGRTVSLFSP AFYTAKYGYK LCLRLYLNGD GTGKRTHLSL FIVIMRGEYD ALLPWPFRNK VTFMLLDQNN REHAIDAFRP DLSSASFQRP QSETNVASGC PLFFPLSKLQ SPKHAYVKDD TMFLKCIVET ST.
• Storage: can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: TRAF1 TNF receptor-associated factor 1 [ Homo sapiens ]
• Synonyms: TNF receptor-associated factor 1; EBI6; MGC:10353; TRAF1; TNF receptor-associated factor 1; Epstein-Bar virus-induced protein 6; epstein-Barr virus-induced protein 6
• Gene ID: 7185
• mRNA Refseq: NM_005658
• Protein Refseq: NP_005649
• MIM: 601711
• UniProt ID: Q13077
• Chromosome Location: 9q33-q34
• Pathway: Pathways in cancer; Small cell lung cancer
• Function: protein binding; zinc ion binding