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Recombinant Human TNF Receptor-associated Factor 1, His-tagged

Cat.No. : TRAF1-2478H
Product Overview : Recombinant human TRAF1 protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. MW = 19.5 kDa (172aa).
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Cat. No. : TRAF1-2478H
Description : TRAF1, also known as TNF receptor-associated factor 1, belongs to TNF receptor superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The complex also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors.
Source : E.coli.
Form : Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 0.1M NaCl,1mM DTT.
Purity : > 95% by SDS – PAGE.
Concentration : 0.5 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids : MGSSHHHHHH SSGLVPRGSH MDGTFLWKIT NVTRRCHESA CGRTVSLFSP AFYTAKYGYK LCLRLYLNGD GTGKRTHLSL FIVIMRGEYD ALLPWPFRNK VTFMLLDQNN REHAIDAFRP DLSSASFQRP QSETNVASGC PLFFPLSKLQ SPKHAYVKDD TMFLKCIVET ST.
Storage : can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Publication :
Silicon Nanowire Biosensor for Highly Sensitive and Multiplexed Detection of Oral Squamous Cell Carcinoma Biomarkers in Saliva. (2015)
Effect of positive end-expiratory pressure after porcine unilateral left lung transplant (2013)
Endogenous IL-8 acts as a CD16 co-activator for natural killer-mediated anti-CD20 B cell depletion in chronic lymphocytic leukemia (2013)
Gene Name : TRAF1 TNF receptor-associated factor 1 [ Homo sapiens ]
Synonyms : TNF receptor-associated factor 1; EBI6; MGC:10353; TRAF1; TNF receptor-associated factor 1; Epstein-Bar virus-induced protein 6; epstein-Barr virus-induced protein 6
Gene ID : 7185
mRNA Refseq : NM_005658
Protein Refseq : NP_005649
MIM : 601711
UniProt ID : Q13077
Chromosome Location : 9q33-q34
Pathway : Pathways in cancer; Small cell lung cancer
Function : protein binding; zinc ion binding

Not For Human Consumption!

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