TRIM24
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Official Full Name
tripartite motif containing 24
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Overview
TIF1beta is a member of the TIF1 (transcriptional intermediary factor 1) family, a group of transcriptional regulators that play key roles in development and differentiation. Members of this family are characterized by the presence of two conserved motifs -
Synonyms
TRIM24; tripartite motif containing 24; TIF1, transcriptional intermediary factor 1 , tripartite motif containing 24; transcription intermediary factor 1-alpha; hTIF1; RNF82; TIF1A; TIF1-alpha; RING finger protein 82; tripartite motif-containing;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Assay Kits
- Human
- Mouse
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
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- Insect Cells
- Mammalian Cell
- Wheat Germ
- Yeast
- Flag
- GST
- His
- His (Fc)
- Avi
- His|Flag
- SUMO
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- TRIM24 Related Signal Pathway
TRIM24 involved in several pathways and played different roles in them. We selected most pathways TRIM24 participated on our site, such as Disease, Diseases of signal transduction, FGFR1 mutant receptor activation, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM24 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Disease | AP2M1;HEY1;OPN1SW;TRIM24;JAG2;TICAM1;KPNA3;GPC6;TH1L |
| Diseases of signal transduction | CPSF6;LRRFIP1;OPN1MW2;FGFR1OP2;TRIM24;OPN1SW;JAG1;RBP1;KREMEN1 |
| FGFR1 mutant receptor activation | MYO18A;LRRFIP1;CUX1;FGFR1OP2;TRIM24;FGFR1OP;CPSF6 |
| Regulation of Androgen receptor activity | APPBP2;SRY;KAT7;SMARCA2;SPDEF;GATA2;NR2C1;NR2C2;SENP1 |
| Signaling by FGFR in disease | CPSF6;MYO18A;TRIM24;FGFR1OP2;LRRFIP1;CUX1 |
| Signaling by FGFR1 fusion mutants | CUX1;CPSF6;MYO18A;FGFR1OP2;TRIM24 |
| Signaling by FGFR1 in disease | CPSF6;TRIM24;CUX1;FGFR1OP2;MYO18A |
TRIM24 has several biochemical functions, for example, chromatin binding, estrogen response element binding, ligand-dependent nuclear receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM24 itself. We selected most functions TRIM24 had, and list some proteins which have the same functions with TRIM24. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| chromatin binding | ARX;TCF7L1B;CCNT1;BARX2;TSHZ3;SMAD6;AJUBA;CBX5;SATB1 |
| estrogen response element binding | TOX3;TRIM24;ESR2;ESR1 |
| ligand-dependent nuclear receptor binding | SLC30A9;NCOA1;NR1H4;TRIP4;ISL1;PROX1;TRIM24;MED1;NCOA3 |
| ligase activity | PCXA;ZNRF3;TTLL4;HERC5;MIB2;ITCH;MDM2;ZNRF2B;TRIM24 |
| lysine-acetylated histone binding | TRIM24;TAF1L;BRD7;PSME4;BRD2;PSME4B;TAF1;SMARCA4;ATAD2B |
| NOT methylated histone binding | CDYL;TRIM24 |
| p53 binding | RNF34;EHMT2;RFWD3;ZMAT4;EHMT1;EP300;HTT;PTTG1IP;PLK3 |
| protein binding | MINK1;ATG7;AHSA2;WIPF1;ADD1;RAB5C;PAPOLA;TEX264;ZFPM2 |
| protein kinase activity | PTK2AA;PRKAG1;ARAF;PKZ;DCKL1B;CCL5;NEK1;RPS6KB2;IKBKAP |
| receptor binding | EPB49;CD200;HAND2;MTSS1;GUSB;CD58;CLCF1;CALCA;PPY |
| sequence-specific DNA binding | HOXC8A;HOXC1A;ZNF35;ARNTL;ISL2;PPARGC1A;FOXG1D;ATF7;HOXB5A |
| transcription coactivator activity | KAT2A;FHL2;GRIP1;CEBPA;PCBD1;GTF2F1;SIX3;RARA;TAF12 |
| ubiquitin protein ligase activity | UBE2KB;CMTM2A;UBE3B;HECW2;MED31;TRIM37;RNF13;BFAR;UBR5 |
| ubiquitin-protein transferase activity | MUL1;FBXL14B;RNF115;RNF10;TRIM28;CBLB;TRIM24;FBXO9;UBR3 |
| zinc ion binding | CLIP1;TRIM35-28;DTNBA;UQCRC1;NR4A1;RARG;KDM5D;TAF2;TRIM35-21 |
TRIM24 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM24 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM24.
HSPB1; BRCA1; UBE2U; RNF141; TRIM8; RNF181; pi3p; ESR1; ESR2; TRIM33
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