|Official Full Name||thioredoxin|
|Background||The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene.|
|Synonyms||TXN; thioredoxin; TRX; ADF; SASP; TXN delta 3; ATL-derived factor; thioredoxin delta 3; surface-associated sulphydryl protein; TRDX; TRX1; MGC61975; DKFZp686B1993|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
txn involved in several pathways and played different roles in them. We selected most pathways txn participated on our site, such as Cellular Senescence, Cellular responses to stress, Detoxification of Reactive Oxygen Species, which may be useful for your reference. Also, other proteins which involved in the same pathway with txn were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Cellular Senescence||PHC2; MAPKAPK2B; MOV10; RING1; AGO3; RBBP7; POT1; HMGA1; CDKN2B; RBBP4|
|Cellular responses to stress||HSBP1; BAG5; AGO3; RRAGA; H3F3B.1; DNAJB6; RRAGB; WIPI2; CBX8A; HIST1H1E|
|Detoxification of Reactive Oxygen Species||TXNRD2; Txn1; PRDX2; TXN; TXN2; PRDX3|
|Folic Acid Network||FMN1; SEPW1; TXN|
|Gene Expression||ZNF493; TNPO1; ZNF689; ZNF839; SMARCA5; SETB; ZFP473; FKBP6; PUS7; GTF3AB|
|Generic Transcription Pathway||ZNF550; MED6; ZNF157; COX14; ZNF12; ESRRG; ZNF286A; ZIK1; NR6A1A; ZKSCAN3|
|Immune System||MYO9B; IFI6; DDOST; UBE2J2; AP1S1; TREM1; C1rb; EIF4E3; NPEPPS; AF251705|
|Inflammasomes||SUGT1; TXNIP; PANX1B; BTR16; BTR22; NLRP3; BTR09; BTR30; TXNIPB; BTR02|
txn has several biochemical functions, for example, disulfide oxidoreductase activity, oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor, protein disulfide oxidoreductase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by txn itself. We selected most functions txn had, and list some proteins which have the same functions with txn. You can find most of the proteins on our site.
|disulfide oxidoreductase activity||DNAJC10; TXNL1; GRX2; TMX1; PDIA3; PDIA2; COIL; TXN|
|oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor||ERO1L; MSRB1B; TXNDC8; TXN2; TXNL1; ERO1LB; DNAJC10; TXN; MSRB1A|
|protein disulfide oxidoreductase activity||ERO1L; PTGES2; TXNRD3; DNAJC10; GRX2; CHCHD4; GSTK1; TXN2; GLRX5; PTGESL|
|peptide disulfide oxidoreductase activity||TXNDC12; Txn1; TXN|
|poly(A) RNA binding||DHX38; PSPC1; ZCRB1; SMNDC1; RPL27; HMGB2; TES; CFAP20; PCBP4; MYBBP1A|
|protein binding||C2orf57; FARSA; TAOK1; NCAM1A; ZBTB24; PARN; RBL2; PDE4DIP; Siglec1; NADSYN1|
txn has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with txn here. Most of them are supplied by our site. Hope this information will be useful for your research of txn.
EGFR; COPS5; slrP; MYD88