txn

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txn

Official Full Name thioredoxin
Background The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms TXN; thioredoxin; TRX; ADF; SASP; TXN delta 3; ATL-derived factor; thioredoxin delta 3; surface-associated sulphydryl protein; TRDX; TRX1; MGC61975; DKFZp686B1993
    • Species :
    • Chicken
    • Human
    • Rhesus Macaque
    • Yeast
    • Zebrafish
    • Source :
    • E. coli
    • E.coli
    • HEK293
    • HEK293T
    • Human
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TXN-004H Recombinant Human TXN (C61S/C72S) Protein E.coli
    Human TXN-155H Recombinant Human TXN Protein E. coli
    Human TXN-018H Recombinant Human TXN Protein E.coli
    Human TXN-019H Recombinant Human TXN Protein E.coli
    Human TXN-020H Recombinant Human TXN Protein E.coli
    Human TXN-2011H Recombinant Human TXN Protein, His-tagged E.coli His
    Human TXN-2132H Recombinant Human TXN Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human TXN-2356H Recombinant Human Thioredoxin, His-tagged E.coli His
    Human TXN-2556H Recombinant Human TXN, None tagged E.coli N/A
    Human TXN-31509TH Recombinant Human TXN E.coli N/A
    Human TXN-31511TH Recombinant Human TXN, His-tagged E.coli His
    Human TXN-3496H Recombinant Human TXN, GST-tagged E.coli GST
    Human TXN-4662H Recombinant Thioredoxin, His-tagged Human His
    Human TXN-627HCL Recombinant Human TXN 293 Cell Lysate HEK293 N/A
    Human TXN-97H Recombinant Human Thioredoxin E.coli N/A
    Human TXN-98H Recombinant Human TXN N/A
    Rhesus Macaque TXN-5036R Recombinant Rhesus monkey TXN Protein, His-tagged Mammalian Cell His
    Chicken TXN-7003C Recombinant Chicken TXN Mammalian Cell His
    Zebrafish TXN-591Z Recombinant Zebrafish TXN Mammalian Cell His
    Yeast LMA1-98Y Recombinant Yeast LMA1 E.coli N/A
    Yeast TRX-263Y Recombinant Yeast Thioredoxin E.coli N/A
    TRX-262 Recombinant Thioredoxin E.coli N/A

    txn involved in several pathways and played different roles in them. We selected most pathways txn participated on our site, such as Cellular Senescence, Cellular responses to stress, Detoxification of Reactive Oxygen Species, which may be useful for your reference. Also, other proteins which involved in the same pathway with txn were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cellular Senescence PHC2; MAPKAPK2B; MOV10; RING1; AGO3; RBBP7; POT1; HMGA1; CDKN2B; RBBP4
    Cellular responses to stress HSBP1; BAG5; AGO3; RRAGA; H3F3B.1; DNAJB6; RRAGB; WIPI2; CBX8A; HIST1H1E
    Detoxification of Reactive Oxygen Species TXNRD2; Txn1; PRDX2; TXN; TXN2; PRDX3
    Folic Acid Network FMN1; SEPW1; TXN
    Gene Expression ZNF493; TNPO1; ZNF689; ZNF839; SMARCA5; SETB; ZFP473; FKBP6; PUS7; GTF3AB
    Generic Transcription Pathway ZNF550; MED6; ZNF157; COX14; ZNF12; ESRRG; ZNF286A; ZIK1; NR6A1A; ZKSCAN3
    Immune System MYO9B; IFI6; DDOST; UBE2J2; AP1S1; TREM1; C1rb; EIF4E3; NPEPPS; AF251705
    Inflammasomes SUGT1; TXNIP; PANX1B; BTR16; BTR22; NLRP3; BTR09; BTR30; TXNIPB; BTR02

    txn has several biochemical functions, for example, disulfide oxidoreductase activity, oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor, protein disulfide oxidoreductase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by txn itself. We selected most functions txn had, and list some proteins which have the same functions with txn. You can find most of the proteins on our site.

    Function Related Protein
    disulfide oxidoreductase activity DNAJC10; TXNL1; GRX2; TMX1; PDIA3; PDIA2; COIL; TXN
    oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor ERO1L; MSRB1B; TXNDC8; TXN2; TXNL1; ERO1LB; DNAJC10; TXN; MSRB1A
    protein disulfide oxidoreductase activity ERO1L; PTGES2; TXNRD3; DNAJC10; GRX2; CHCHD4; GSTK1; TXN2; GLRX5; PTGESL
    peptide disulfide oxidoreductase activity TXNDC12; Txn1; TXN
    poly(A) RNA binding DHX38; PSPC1; ZCRB1; SMNDC1; RPL27; HMGB2; TES; CFAP20; PCBP4; MYBBP1A
    protein binding C2orf57; FARSA; TAOK1; NCAM1A; ZBTB24; PARN; RBL2; PDE4DIP; Siglec1; NADSYN1

    txn has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with txn here. Most of them are supplied by our site. Hope this information will be useful for your research of txn.

    EGFR; COPS5; slrP; MYD88

    Singh, P; Feld, RI; et al. Sensitization, pathologic, and imaging findings comparing symptomatic and quiescent failed renal allografts. CLINICAL TRANSPLANTATION 28:1424-1432(2014).
    Negroni, L; Taouji, S; et al. Integrative Quantitative Proteomics Unveils Proteostasis Imbalance in Human Hepatocellular Carcinoma Developed on Nonfibrotic Livers. MOLECULAR & CELLULAR PROTEOMICS 13:3473-3483(2014).

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