Recombinant Human TXN Protein


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Recombinant Human TXN Protein

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Cat.No. : TXN-018H
Product Overview : Recombinant Mutant Human TXN protein (Mutant C61S/C72S) without tag was expressed in E. coli. This is a mutant form of human thioredoxin, which lacks the structural cysteine residues C61 and C72, which are responsible for oxidative inactivation and dimer formation. The active site: C31 and C34.
Description : The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene.
Source : E. coli
Species : Human
Form : Lyophilized
Stability : ≥ 6 months
Storage : 4 centigrade
Storage Buffer : 50 mM tris-HCl, pH 7.5, 1 mM EDTA
Reconstitution : Reconstitute with 100 μL H2O. This gives a solution of 210 μM thioredoxin. The protein may partly be oxidized and can be reactivated by addition of a 5-fold molar excess of DTT or by use of Reductacryl®reagent.
Gene Name : TXN thioredoxin [ Homo sapiens (human) ]
Official Symbol : TXN
Synonyms : TXN; thioredoxin; TRX; TRDX; TRX1; thioredoxin; ADF; ATL-derived factor; SASP; TXN delta 3; surface-associated sulphydryl protein; testicular tissue protein Li 199; thioredoxin delta 3
Gene ID : 7295
mRNA Refseq : NM_001244938
Protein Refseq : NP_001231867
MIM : 187700
UniProt ID : P10599

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