Recombinant Human UBE2C

• Cat.No.: UBE2C-118H
• Product Overview: Recombinant Human UBE2C was expressed in E.coli.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Form: Liquid, 25 mM Tris, pH 7.4; 150 mM NaCl; 10 mM DTT; 10% glycerol
• Molecular Mass: 19,652.6 Da by MS (calculated 19,652.3)
• Purity: >95% by RP-HPLC
• Applications: Identify cognate E2/E3 pairsCharacterize upregulation/downregulation of E2 enzymesBuild poly-ubiquitin chainsCharacterize ubiquitin chain specificity of E2 enzymesAnalyze expression of E2 enzymes
• Storage: Store at -80℃. Avoid repeated freeze/thaw cycles.

Gene Information

• Gene Name: UBE2C ubiquitin-conjugating enzyme E2C [ Homo sapiens ]
• Official Symbol: UBE2C
• Synonyms: UBE2C; ubiquitin-conjugating enzyme E2C; ubiquitin-conjugating enzyme E2 C; UBCH10; ubiquitin-protein ligase C; ubiquitin carrier protein C; ubiquitin carrier protein E2-C; cyclin-selective ubiquitin carrier protein; mitotic-specific ubiquitin-conjugating enzyme; dJ447F3.2
• Gene ID: 11065
• mRNA Refseq: NM_007019
• Protein Refseq: NP_008950
• MIM: 605574
• UniProt ID: O00762
• Chromosome Location: 20q13.12
• Pathway: APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Cyclin B, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Securin, organism-specific biosystem; APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, organism-specific biosystem; Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem
• Function: ATP binding; acid-amino acid ligase activity; ligase activity; nucleotide binding; protein binding; ubiquitin-protein ligase activity; contributes_to ubiquitin-protein ligase activity