USP7 Protein


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Official Full Name ubiquitin specific peptidase 7 (herpes virus-associated)
Background Ubiquitin carboxyl-terminal hydrolase 7 (USP7) is a ubiquitin specific protease or a deubiquitylating enzyme that cleaves ubiquitin from its substrates.[Saridakis, 2005] Since ubiquitylation (polyubiquitination) is most commonly associated with the stability and degradation of cellular proteins, Ubiquitin carboxyl-terminal hydrolase 7 activity generally stabilizes its substrate proteins. Ubiquitin carboxyl-terminal hydrolase 7 is most popularly known as a direct antagonist of Mdm2, the E3 ubiquitin ligase for the tumor suppressor protein, p53.[Canning, 2004]
Synonyms USP7; ubiquitin specific peptidase 7 (herpes virus-associated); HAUSP, ubiquitin specific protease 7 (herpes virus associated); ubiquitin carboxyl-terminal hydrolase 7; ubiquitin thioesterase 7; deubiquitinating enzyme 7; ubiquitin-specific-processing protease 7; herpesvirus-associated ubiquitin-specific protease; Herpes virus-associated ubiquitin-specific protease; ubiquitin specific protease 7 (herpes virus-associated); TEF1; HAUSP
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Insect Cell
    • Mammalian Cell
    • Mammalian cells
    • Mouse
    • Tag :
    • Flag
    • GST
    • His
    • His-SUMO & Myc
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human USP7-490H Active Recombinant Human USP7 protein, His-tagged E.coli His Inquiry
    Human USP7-922H Active Recombinant Human USP7 protein, His-tagged Insect Cell His Inquiry
    Human USP7-29182TH Recombinant Human USP7, His-tagged E.coli His Inquiry
    Human USP7-319H Recombinant Human USP7 protein, GST-tagged E.coli GST Inquiry
    Human USP7-320H Recombinant Human USP7 protein, His-tagged E.coli His Inquiry
    Human USP7-924H Recombinant Human USP7, His & GST tagged Insect Cell His/GST Inquiry
    Human USP7-925H Recombinant Human USP7, His & GST tagged Insect Cell His/GST Inquiry
    Human USP7-926H Recombinant Human USP7, None tagged Insect Cell N/A Inquiry
    Rat USP7-6480R Recombinant Rat USP7 Protein Mammalian Cell His Inquiry
    Chicken USP7-6041C Recombinant Chicken USP7 Mammalian Cell His Inquiry
    Human USP7-671HCL Recombinant Human USP7 cell lysate Insect Cell N/A Inquiry
    Human USP7-672HCL Recombinant Human USP7 cell lysate Insect Cell N/A Inquiry
    Human USP7-02H Recombinant Human USP7 Protein, His-tagged E.coli His Inquiry
    Human USP7-4717H Recombinant Human USP7 protein, His-SUMO & Myc-tagged E.coli His-SUMO & Myc Inquiry
    Human USP7-807HFL Recombinant Full Length Human USP7 Protein, C-Flag-tagged Mammalian cells Flag Inquiry
    Human CAB11623MH Mouse Monoclonal Antibody to Human Ubiquitin Specific Peptidase 7 Mouse N/A Inquiry
    Human USP7-457H Recombinant Human USP7 protein, His-tagged E.coli His Inquiry
    Human USP7-5967H Recombinant Human USP7 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK Inquiry
    Human USP7-677H Recombinant Human USP7 Protein, MYC/DDK-tagged HEK293 Myc/DDK Inquiry
    Mouse Usp7-6882M Recombinant Mouse Usp7 Protein, Myc/DDK-tagged HEK293T Myc/DDK Inquiry
    CBCRY35 Ubiquitin Carboxyl-terminal Hydrolase 7 E.coli N/A Inquiry

    USP7 involved in several pathways and played different roles in them. We selected most pathways USP7 participated on our site, such as FoxO signaling pathway, Herpes simplex infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with USP7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    FoxO signaling pathway MAPK3; FOXO3; FOXO1B; EGFRA; SMAD3A; GABARAP; PCK2; RAG2; TNFSF10; SMAD2
    Herpes simplex infection PML; GTF2I; ARNTL; MAPK9; OAS3; H2-AB1; NXF2; IL12BA; HLA-C; EIF2AK3

    USP7 has several biochemical functions, for example, ubiquitin-specific protease activity. Some of the functions are cooperated with other proteins, some of the functions could acted by USP7 itself. We selected most functions USP7 had, and list some proteins which have the same functions with USP7. You can find most of the proteins on our site.

    Function Related Protein
    ubiquitin-specific protease activity OTUD6A; USP17L2; USP38; USP20; USP15; USP37; CYLD; USP33; OTUD3; USP50

    USP7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with USP7 here. Most of them are supplied by our site. Hope this information will be useful for your research of USP7.

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