Recombinant Human USP7 Protein, MYC/DDK-tagged

Cat.No. : USP7-677H
Product Overview : Recombinant human USP7 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.
  • Specification
  • Gene Information
  • Related Products
  • Download
Description : The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder. [provided by RefSeq, Mar 2016]
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Molecular Mass : 128.1 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : ubiquitin specific peptidase 7[ Homo sapiens ]
Official Symbol : USP7
Synonyms : HAUSP; TEF1
Gene ID : 7874
mRNA Refseq : NM_003470.2
Protein Refseq : NP_003461.2
MIM : 602519
UniProt ID : Q93009

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Reviews
  • Q&As

Customer Reviews (3)

Write a review
Reviews
10/22/2021

    The product's widespread recognition among researchers made it a preferred choice for many scientific studies.

    06/17/2018

      Positive feedback from other labs and researchers confirmed its standing as a valuable research tool.

      06/28/2016

        The product's respected reputation in the scientific community was a testament to its quality and effectiveness.

        Q&As (7)

        Ask a question
        Does USP7 interact with specific protein substrates? 12/02/2022

        Yes, USP7 interacts with various protein substrates, including p53, MDM2, and PTEN, influencing their stability and cellular functions.

        Can USP7 inhibitors be potential cancer therapeutics? 08/04/2022

        Inhibitors targeting USP7 are being explored as potential cancer therapeutics, aiming to disrupt the stability of oncogenic proteins and inhibit cancer cell growth.

        Does USP7 have tissue-specific expression patterns? 03/29/2021

        USP7 exhibits tissue-specific expression patterns, and its levels may vary in different tissues and cell types.

        What is the significance of USP7 in neurodegenerative diseases? 02/03/2020

        USP7 has been implicated in neurodegenerative diseases, and its dysregulation may contribute to protein aggregation and neuronal dysfunction.

        Are there post-translational modifications of USP7? 06/17/2019

        Yes, USP7 undergoes post-translational modifications, including phosphorylation and ubiquitination, which can regulate its activity and stability.

        How does USP7 regulate the p53 pathway? 04/24/2018

        USP7 regulates the p53 pathway by deubiquitinating and stabilizing p53, preventing its degradation and promoting its transcriptional activity.

        Is USP7 involved in the immune response? 02/18/2018

        Yes, USP7 plays a role in the immune response by regulating the stability of proteins involved in immune signaling pathways.

        Ask a Question for All USP7 Products

        Required fields are marked with *

        My Review for All USP7 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /
        • Service lnquiry:

        Stay Updated on the Latest Bioscience Trends