Recombinant Human USP7 protein, His-tagged

• Cat.No.: USP7-320H
• Product Overview: Recombinant human USP7 (25-580 amino acid) was expressed in E.coli cells using an N-terminal His tag.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 25-580 a.a.
• Description: USP7 (also called HAUSP) deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal degradation.
• Form: 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol
• Molecular Mass: 68~72 kDa
• Purity: The purity of USP7 was determined to be >75% by densitometry.
• Applications: Enzyme Assay; WB
• Stability: 1 year at -70 centigrade
• Storage: Store product at -70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.1 μg/μL

Gene Information

• Gene Name: ubiquitin specific peptidase 7 [ Homo sapiens (human) ]
• Official Symbol: USP7
• Synonyms: TEF1; HAUSP; USP7
• Gene ID: 7874
• mRNA Refseq: NM_003470
• Protein Refseq: NP_003461
• MIM: 602519
• UniProt ID: Q93009