Recombinant Human USP7 Protein, His-tagged USP7-02H

Recombinant Human USP7 Protein, His-tagged

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Recombinant Human USP7 Protein, His-tagged

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Cat.No. : USP7-02H Optional Service: Optional requirements on this protein
Product Overview : Recombinant Human USP7 Protein, fused to His-tag, was expressed in E. coli.
Description : The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder.
Source : E. coli
Species : Human
Tag : His
Form : 50 mM HEPES pH 7.5, 150 mM sodium chloride, 2 mM dithiothreitol, 10% glycerol.
Molecular Mass : ~130 kDa
AA Sequence : MGSSHHHHHHSSG LEVLFQGP G S M N HQQQQQQQKAGEQQLSEPEDMEMEAGDTD DPPRITQNPVINGNVALSDGHNTAEEDMED DTSWRSEATFQFTVERFSRLSESVLSPP CFVRNLPWKIMVMPRFYPDRPHQKSVGF FLQCNAESDSTSWSCHAQAVLKIINYRD DEKSFSRRISHLFFHKENDWGFSNFMAWSEVT DPEKGFIDDDKVTFEVFVQADAPHGVAWDSK KHTGYVGLKNQGATCYMNSLLQTLFFTNQL RKAVYMMPTEGDDSSKSVPLALQRVFYELQHS DKPVGTKKLTKSFGWETLDSFMQHDVQEL CRVLLDNVENKMKGTCVEGTIPKLFRGKM VSYIQCKEVDYRSDRREDYYDIQLSIKGK KNIFESFVDYVAVEQLDGDNKYDAGEHGLQE AEKGVKFLTLPPVLHLQLMRFMYDPQTDQNI KINDRFEFPEQLPLDEFLQKTDPKDPANYIL HAVLVHSGDNHGGHYVVYLNPKGDGKW CKFDDDVVSRCTKEEAIEHNYGGHDDDLS VRHCTNAYMLVYIRESKLSEVLQAVTDHDI PQQLVERLQEEKRIEAQKRKERQEAHLYMQVQ IVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNS SLAEFVQSLSQTMGFPQDQIRLWPMQARSNGT KRPAMLDNEADGNKTMIELSDNENPWTIFLET VDPELAASGATLPKFDKDHDVMLFLKMYDPK TRSLNYCGHIYTPISCKIRDLLPVMCDRAG FIQDTSLILYEEVKPNLTERIQDYDVSLDKA LDELMDGDIIVFQKDDPENDNSELPTAKEY FRDLYHRVDVIFCDKTIPNDPGFVVTLSNRM NYFQVAKTVAQRLNTDPMLLQFFKSQGYRDG PGNPLRHNYEGTLRDLLQFFKPRQPKKLYY QQLKMKITDFENRRSFKCIWLNSQFREEEIT LYPDKHGCVRDLLEECKKAVELGEKASGKL RLLEIVSYKIIGVHQEDELLECLSPATSRT FRIEEIPLDQVDIDKENEMLVTVAHFHKEV FGTFGIPFLLRIHQGEHFREVMKRIQSLL DIQEKEFEKFKFAIVMTGRHQYINEDEYEVN LKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRY TYLEKAIKIHN
Purity : >80%
Storage : 12 months at -70 centigrade; aliquot as required.
Concentration : 0.5 mg/ml
4-12% gradient SDS-PAGE InstantBlue™ staining. :

Lane 1: MW markers
Lane 2: 1 µg His-USP7

Gene Name : USP7 ubiquitin specific peptidase 7 [ Homo sapiens (human) ]
Official Symbol : USP7
Synonyms : TEF1; HAUSP; HAFOUS
Gene ID : 7874
mRNA Refseq : NM_001286457
Protein Refseq : NP_001273386
MIM : 602519
UniProt ID : Q93009
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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