VASP

  • Official Full Name

    VASP vasodilator-stimulated phosphoprotein
  • Overview

    VASP (vasodilator stimulated phosphoprotein) plays an important role in ANF/NO/cGMP Protein kinase and cAMP/cAMP Protein kinase signalling pathways. VASP is expressed in almost all human and animal cell lines; particularly high concentrations are found in thrombocytes, vascular smooth muscle cells and fibroblasts. In cultured cells VASP is associated with focal contacts, cell-cell-contacts, microfilaments and dynamic membrane regions such as the leading edge. In vitro binding data show that VASP binds to profilin, zyxin, vinculin, and the Listeria spp. surface protein ActA. Functional evidence indicates that VASP is a crucial factor involved in the enhancement of actin filament formation.
  • Synonyms

    VASP;vasodilator-stimulated phosphoprotein

Recombinant Proteins

  • Mouse
  • Human
  • Mammalian Cells
  • E.coli
  • HEK293
  • Yeast
  • Baculovirus
  • His
  • Non
  • Flag
  • DDK
  • Myc
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
VASP-17986M Recombinant Mouse VASP Protein Mammalian Cells Mouse His
VASP-30994TH Recombinant Human VASP, His-tagged E.coli Human His 343 amino acids
VASP-3500H Recombinant Human VASP, His-tagged E.coli Human His
VASP-426HCL Recombinant Human VASP 293 Cell Lysate HEK293 Human Non
VASP-1409HFL Recombinant Full Length Human VASP Protein, C-Flag-tagged Mammalian Cells Human Flag Full L.
VASP-1570H Recombinant Human VASP Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
VASP-2332H Recombinant Human VASP Protein, His (Fc)-Avi-tagged HEK293 Human Avi&Fc&His
VASP-2332H-B Recombinant Human VASP Protein Pre-coupled Magnetic Beads HEK293 Human
Vasp-4907M Recombinant Mouse Vasp protein Yeast Mouse Non 2-375 aa
Vasp-4908M Recombinant Mouse Vasp protein, Avi-tagged, Biotinylated E.coli Mouse Avi 2-375 aa
Vasp-4909M Recombinant Mouse Vasp protein Baculovirus Mouse Non 2-375 aa
Vasp-4910M Recombinant Mouse Vasp protein Mammalian Cells Mouse Non 2-375 aa
Vasp-6322M Recombinant Mouse Vasp protein, His-tagged E.coli Mouse His 2-375aa
Vasp-6901M Recombinant Mouse Vasp Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
VASP-9999M Recombinant Mouse VASP Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
VASP-9999M-B Recombinant Mouse VASP Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    VASP involved in several pathways and played different roles in them. We selected most pathways VASP participated on our site, such as Rap signaling pathway,cGMP-PKG signaling pathway,Focal adhesion, which may be useful for your reference. Also, other proteins which involved in the same pathway with VASP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    cGMP-PKG signaling pathway PLCB1,PPP1CC,TRPC6,PPP1CB,PDE5A,PLCB3,CREB3L2,ATP2A1,PPP1R12A,CALM3
    Focal adhesion GRB2,PAK2B,ACTN3B,MYL9B,LAMB4,PTEN,PDGFRA,THBS1,RAC1A,TNW
    Platelet activation ACTG1,MAPK1,RHOA,COL24A1,MAPK3,GP1BA,SRC,PPP1R12A,PPP1CB,GP5
    Fc gamma R-mediated phagocytosis NCF1,PPAP2C,PIK3CA,VAV3,CFL1,PLD2,cgr2b,PRKCB,PRKCA,MAP2K1
    Leukocyte transendothelial migration MAPK11,CXCR4,CLDN17,ACTN1,RAP1B,GNAI3,CLDN9,OCLN,CLDN11,RHOA
    Rap signaling pathway DOCK4,FLT4,FGF8,KLK1B4,FGF4,MET,ITGB2,FGF20,GNAS,CALM2

    Protein Function

    VASP has several biochemical functions, for example, SH3 domain binding,actin binding,profilin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by VASP itself. We selected most functions VASP had, and list some proteins which have the same functions with VASP. You can find most of the proteins on our site.

    Function Related Protein
    actin binding SPNA1,FKBP15,PLEC,MYH7B,VPS18,MYH9,DBNL,CLMN,INPPL1A,EVL
    protein binding MEIOB,ZNF622,PLEKHF1,VEGFB,EP400,CREB5,APBB3,BAD,PAGE1,LGR6
    SH3 domain binding RAD9,REPS1,GRIK5,QKIA,ADAM9,SH3BP5B,QKI2,SH3BP5L,ITGB1BP2,SH3BGRL
    profilin binding WIPF1,FMNL1,DIAPH1,DIAP1,EVL,HTT,CYFIP1,CTTN,RHOQ,PCLO

    Interacting Protein

    VASP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VASP here. Most of them are supplied by our site. Hope this information will be useful for your research of VASP.

    XIRP1;BAIAP2;FGFR1OP;SCGB2A2;ABI2

    Resources

    Research Area

    References

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