vasp Protein, VASP vasodilator-stimulated phosphoprotein

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vasp

Official Full Name	VASP vasodilator-stimulated phosphoprotein
Background	VASP (vasodilator stimulated phosphoprotein) plays an important role in ANF/NO/cGMP Protein kinase and cAMP/cAMP Protein kinase signalling pathways. VASP is expressed in almost all human and animal cell lines; particularly high concentrations are found in thrombocytes, vascular smooth muscle cells and fibroblasts. In cultured cells VASP is associated with focal contacts, cell-cell-contacts, microfilaments and dynamic membrane regions such as the leading edge. In vitro binding data show that VASP binds to profilin, zyxin, vinculin, and the Listeria spp. surface protein ActA. Functional evidence indicates that VASP is a crucial factor involved in the enhancement of actin filament formation.
Synonyms	VASP; vasodilator-stimulated phosphoprotein;

Species :
Human
Mouse

Source :
E.coli
HEK293
HEK293T
Mammalian Cell

Tag :
His
Myc/DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag
Human	VASP-1570H	Recombinant Human VASP Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK
Mouse	Vasp-6901M	Recombinant Mouse Vasp Protein, Myc/DDK-tagged	HEK293T	Myc/DDK
Human	VASP-30994TH	Recombinant Human VASP, His-tagged	E.coli	His
Human	VASP-3500H	Recombinant Human VASP, His-tagged	E.coli	His
Human	VASP-426HCL	Recombinant Human VASP 293 Cell Lysate	HEK293	N/A
Mouse	VASP-17986M	Recombinant Mouse VASP Protein	Mammalian Cell	His

Involved Pathway Protein Function Interacting Protein

vasp involved in several pathways and played different roles in them. We selected most pathways vasp participated on our site, such as Rap signaling pathway, cGMP-PKG signaling pathway, Focal adhesion, which may be useful for your reference. Also, other proteins which involved in the same pathway with vasp were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Rap signaling pathway	PIK3CA; LPAR4; FLT1; LAT; KRIT1; ITGAM; GNAQ; FGF22; ITGA2B; FGF16
cGMP-PKG signaling pathway	BNP; PIK3CA; MYLK; IRS1; NFATC3; CREB3L1; CREB5; INS; ATP1B4; GNAI2
Focal adhesion	SEPP1; ITGA11A; RHOAC; RAP1A; RAF1; LAMC3; VCLA; THBS4; ARHGAP5; PPP1CAA
Platelet activation	RAP1A; VASP; FGG; FGB; ITPR1; PLCB4; MYLK2; RHOA; NOS3; PRKG2
Fc gamma R-mediated phagocytosis	MARCKSL1; BIN1; PIK3CD; LAT; PPAP2A; ASAP2; PLCG2; PIP5K1B; PIK3R3; PTPRC
Leukocyte transendothelial migration	BCAR1; ACTN3; CLDN14; RAC1; ROCK2; ACTN1; MLLT4; PIK3R2; Itgam&Itgb2; RHOA

vasp has several biochemical functions, for example, SH3 domain binding, actin binding, profilin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by vasp itself. We selected most functions vasp had, and list some proteins which have the same functions with vasp. You can find most of the proteins on our site.

Function	Related Protein
SH3 domain binding	PTTG1; RAD9; SH3BP5LA; ABL1; ARHGAP1; CBLC; UVRAG; ADAM10; ITGB1BP2; SH3BP5
actin binding	EPS8; CYFIP1; SSH2; CORO2B; CFL2L; INPPL1; MYH7B; MYO5C; EMD; SMTN
profilin binding	FMNL1; CTTN; EVL; HTT; DIAP1; DIAPH1; RHOQ; WIPF1; PCLO; VASP
protein binding	PRX; VEGFAB; KLF5; PTPRO; EXOSC7; GTF3C3; MALSU1; TSTD2; GRIN3A; SGPL1

vasp has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with vasp here. Most of them are supplied by our site. Hope this information will be useful for your research of vasp.

XIRP1; BAIAP2; FGFR1OP; SCGB2A2; ABI2

vasp

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vasp

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